New antibiotics from Nature's chemical inventory

Bioorganic and Medicinal Chemistry

Volumn 24, Issue 24, 2016, Pages 6227-6252

  Wencewicz, Timothy A ^a  

^a WASHINGTON UNIVERSITY   (United States)

Author keywords

Antibiotics; Biosynthesis; Drug discovery; Essential genes; Genome mining; Metabolomics; Natural products; Resistance; Smart screens

Indexed keywords

ANTIBIOTIC AGENT; ASPERGILLOMARASMINE; BACITRACIN; BAICALEIN; BAMBERMYCIN; BAULAMYCIN A; BINDING PROTEIN; CALGRANULIN; DAPTOMYCIN; FIDAXOMICIN; GUADINOMINE A; KIBDELOMYCIN; LACTIVICIN; LACTOCILLIN; LASSOMYCIN; LYSOBACTIN; MANNOPEPTIDMYCIN; NISIN; PLUSBACIN; POLYMYXIN; PSEUDOMONIC ACID; RETAPAMULIN; SIDEROCALIN; TEICOPLANIN; TEIXOBACTIN; TELOMYCIN; THANAMYCIN; TSUSHIMYCIN; TUNICAMYCIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; ANTIINFECTIVE AGENT; BIOLOGICAL PRODUCT;

ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; ARTICLE; CLOSTRIDIUM DIFFICILE INFECTION; DNA HOMEOSTASIS; DRUG APPROVAL; DRUG EFFICACY; DRUG POTENCY; FOOD AND DRUG ADMINISTRATION; GENE EXPRESSION; GENE SILENCING; HIGH THROUGHPUT SCREENING; HOMEOSTASIS; HUMAN; LIPOGENESIS; METABOLOMICS; METAGENOMICS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; MYOPATHY; NONHUMAN; POLYMERASE CHAIN REACTION; POLYPHARMACOLOGY; PROTEIN ASSEMBLY; PROTEIN HOMEOSTASIS; QUORUM SENSING; RNA HOMEOSTASIS; SKIN INFECTION; CHEMISTRY;

ANTI-BACTERIAL AGENTS; BIOLOGICAL PRODUCTS; HIGH-THROUGHPUT SCREENING ASSAYS;

EID: 85002341700     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2016.09.014     Document Type: Article

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