Initial sequencing and analysis of the human genome

Nature

Volumn 409, Issue 6822, 2001, Pages 860-921

  Lander, Eric S ^a   Linton, Lauren M ^a   Birren, Bruce ^a   Nusbaum, Chad ^a   Zody, Michael C ^a   Baldwin, Jennifer ^a   Devon, Keri ^a   Dewar, Ken ^a   Doyle, Michael ^a   Fitzhugh, William ^a   Funke, Roel ^a   Gage, Diane ^a   Harris, Katrina ^a   Heaford, Andrew ^a   Howland, John ^a   Kann, Lisa ^a   Lehoczky, Jessica ^a   Levine, Rosie ^a   McEwan, Paul ^a   McKernan, Kevin ^a   Meldrim, James ^a   Mesirov, Jill P ^a   Miranda, Cher ^a   Morris, William ^a   Naylor, Jerome ^a   Raymond, Christina ^a   Rosetti, Mark ^a   Santos, Ralph ^a   Sheridan, Andrew ^a   Sougnez, Carrie ^a   Stange Thomann, Nicole ^a   Stojanovic, Nikola ^a   Subramanian, Aravind ^a   Wyman, Dudley ^a   Rogers, Jane ^b   Sulston, John ^b   Ainscough, Rachael ^b   Beck, Stephan ^b   Bentley, David ^b   Burton, John ^b   Clee, Christopher ^b   Carter, Nigel ^b   Coulson, Alan ^b   Deadman, Rebecca ^b   Deloukas, Panos ^b   Dunham, Andrew ^b   Dunham, Ian ^b   Durbin, Richard ^b   French, Lisa ^b   Grafham, Darren ^b   Gregory, Simon ^b   Hubbard, Tim ^b   Humphray, Sean ^b   Hunt, Adrienne ^b   Jones, Matthew ^b   Lloyd, Christine ^b   McMurray, Amanda ^b   Matthews, Lucy ^b   Mercer, Simon ^b   Milne, Sarah ^b   Mullikin, James C ^b   Mungall, Andrew ^b   Plumb, Robert ^b   Ross, Mark ^b   Shownkeen, Ratna ^b   Sims, Sarah ^b   Waterston, Robert H ^c   Wilson, Richard K ^c   Hillier, Ladeana W ^c   McPherson, John D ^c   Marra, Marco A ^c   Mardis, Elaine R ^c   Fulton, Lucinda A ^c   Chinwalla, Asif T ^c   Pepin, Kymberlie H ^c   Gish, Warren R ^c   Chissoe, Stephanie L ^c   Wendl, Michael C ^c   Delehaunty, Kim D ^c   Miner, Tracie L ^c   Delehaunty, Andrew ^c   Kramer, Jason B ^c   Cook, Lisa L ^c   Fulton, Robert S ^c   Johnson, Douglas L ^c   Minx, Patrick J ^c   Clifton, Sandra W ^c   Hawkins, Trevor ^d   Branscomb, Elbert ^d   Predki, Paul ^d   Richardson, Paul ^d   Wenning, Sarah ^d   Slezak, Tom ^d   Doggett, Norman ^d   Cheng, Jan Fang ^d   Olsen, Anne ^d   Lucas, Susan ^d   Elkin, Christopher ^d   Uberbacher, Edward ^d   Frazier, Marvin ^d   Gibbs, Richard A ^e   Muzny, Donna M ^e   Scherer, Steven E ^e   Bouck, John B ^e   Sodergren, Erica J ^e   Worley, Kim C ^e   Rives, Catherine M ^e   Gorrell, James H ^e   Metzker, Michael L ^e   Naylor, Susan L ^f   Kucherlapati, Raju S ^g   Nelson, David L ^h   Weinstock, George M ^h   Sakaki, Yoshiyuki ⁱ   Fujiyama, Asao ⁱ   Hattori, Masahira ⁱ   Yada, Tetsushi ⁱ   Toyoda, Atsushi ⁱ   Itoh, Takehiko ⁱ   Kawagoe, Chiharu ⁱ   Watanabe, Hidemi ⁱ   Totoki, Yasushi ⁱ   Taylor, Todd ⁱ   Weissenbach, Jean ^j   Heilig, Roland ^j   Saurin, William ^j   Artiguenave, Francois ^j   Brottier, Philippe ^j   Bruls, Thomas ^j   Pelletier, Eric ^j   Robert, Catherine ^j   Wincker, Patrick ^j   Rosenthal, André ^l   Platzer, Matthias ^l   Nyakatura, Gerald ^l   Taudien, Stefan ^l   Rump, Andreas ^l   Smith, Douglas R ^k   Doucette Stamm, Lynn ^k   Rubenfield, Marc ^k   Weinstock, Keith ^k   Hong, Mei Lee ^k   Dubois, Joann ^k   Yang, Huanming ^m   Yu, Jun ^m   Wang, Jian ^m   Huang, Guyang ⁿ   Gu, Jun ⁿ   Hood, Leroy ^o   Rowen, Lee ^o   Madan, Anup ^o   Qin, Shizen ^o   Davis, Ronald W ^p   Federspiel, Nancy A ^p   Abola, A Pia ^p   Proctor, Michael J ^p   Roe, Bruce A ^t   Chen, Feng ^t   Pan, Huaqin ^t   Ramser, Juliane ^u   Lehrach, Hans ^u   Reinhardt, Richard ^u   McCombie, W Richard ^v   De La Bastide, Melissa ^v   Dedhia, Neilay ^v   Blöcker, Helmut ^w   Hornischer, Klaus ^w   Nordsiek, Gabriele ^w   Agarwala, Richa ^x   Aravind, L ^x   Bailey, Jeffrey A ^y   Bateman, Alex ^b   Batzoglou, Serafim ^a   Birney, Ewan ^z   Bork, Peer ^aa,ab   Brown, Daniel G ^a   Burge, Christopher B ^ac   Cerutti, Lorenzo ^z,an   Chen, Hsiu Chuan ^x   Church, Deanna ^x   Clamp, Michele ^b   Copley, Richard R ^ab   Doerks, Tobias ^aa,ab   Eddy, Sean R ^c   Eichler, Evan E ^y   Furey, Terrence S ^ad   Galagan, James ^a   Gilbert, James G R ^b   Harmon, Cyrus ^ae   Hayashizaki, Yoshihide ⁱ   Haussler, David ^ad   Hermjakob, Henning ^z   Hokamp, Karsten ^af   Jang, Wonhee ^x   Johnson, L Steven ^c   Jones, Thomas A ^c   Kasif, Simon ^ac   Kaspryzk, Arek ^z   Kennedy, Scot ^ag   Kent, W James ^ag   Kitts, Paul ^x   Koonin, Eugene V ^x   Korf, Ian ^c   Kulp, David ^ae   Lancet, Doron ^ah   Lowe, Todd M ^p   McLysaght, Aoife ^af   Mikkelsen, Tarjei ^ac   Moran, John V ^ai   Mulder, Nicola ^z   Pollara, Victor J ^a   Ponting, Chris P ^aj   Schuler, Greg ^x   Schultz, Jörg ^ab   Slater, Guy ^z   Smit, Arian F A ^o   Stupka, Elia ^z   Szustakowki, Joseph ^ac   Thierry Mieg, Danielle ^x   Thierry Mieg, Jean ^x   Wagner, Lukas ^x   Wallis, John ^c   Wheeler, Raymond ^ae   Williams, Alan ^ae   Wolf, Yuri I ^x   Wolfe, Kenneth H ^af   Yang, Shiaw Pyng ^c   Yeh, Ru Fang ^ac   Collins, Francis ^ak   Guyer, Mark S ^ak   Peterson, Jane ^ak   Felsenfeld, Adam ^ak   Wetterstrand, Kris A ^ak   Myers, Richard M ^p   Schmutz, Jeremy ^p   Dickson, Mark ^p   Grimwood, Jane ^p   Cox, David R ^p   Olson, Maynard V ^q   Kaul, Rajinder ^q   Raymond, Christopher ^q   Shimizu, Nobuyoshi ^r   Kawasaki, Kazuhiko ^r   Minoshima, Shinsei ^r   Evans, Glen A ^s,am   Athanasiou, Maria ^s   Schultz, Roger ^s   Patrinos, Aristides ^al   Morgan, Michael J ^z   more..

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d DOE JOINT GENOME INSTITUTE   (United States)

^e BAYLOR COLLEGE OF MEDICINE   (United States)

^f UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^g ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^h UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

ⁱ RIKEN YOKOHAMA INSTITUTE   (Japan)

^j CENTRE NATIONAL DE SÉQUENÇAGE   (France)

^k GENOME THERAPEUTICS CORPORATION   (United States)

^l FRITZ LIPMANN INSTITUTE   (Germany)

^m INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

ⁿ CHINESE NATIONAL HUMAN GENOME CENTER AT SHANGHAI   (China)

^o INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^p STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^q UNIVERSITY OF WASHINGTON   (United States)

^r KEIO UNIVERSITY   (Japan)

^s UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^t UNIVERSITY OF OKLAHOMA   (United States)

^u MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^v Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^w HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^x NATIONAL INSTITUTES OF HEALTH   (United States)

^y CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^z WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^aa MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^ab EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^ac MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^ad University of California Santa Cruz   (United States)

^ae Thermo Fisher Scientific   (United States)

^af TRINITY COLLEGE DUBLIN   (Ireland)

^ag UNIVERSITY OF CALIFORNIA   (United States)

^ah WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^ai UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^aj UNIVERSITY OF OXFORD   (United Kingdom)

^ak NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^al U S DEPARTMENT OF ENERGY   (United States)

^am Egea Biosciences   (United States)

^an CEMAGREF   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CPG ISLAND; DATA BASE; DEVELOPMENT; EVOLUTION; GENE SEQUENCE; GENETIC ANALYSIS; HUMAN; HUMAN GENETICS; MEDICAL GENETICS; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE REPEAT; PRIORITY JOURNAL; TRANSPOSON;

ANIMALS; CHROMOSOME MAPPING; CONSERVED SEQUENCE; CPG ISLANDS; DATABASES, FACTUAL; DNA TRANSPOSABLE ELEMENTS; DRUG INDUSTRY; EVOLUTION, MOLECULAR; FORECASTING; GC RICH SEQUENCE; GENE DUPLICATION; GENES; GENETIC DISEASES, INBORN; GENETICS, MEDICAL; GENOME, HUMAN; HUMAN GENOME PROJECT; HUMANS; MUTATION; PRIVATE SECTOR; PROTEINS; PROTEOME; PUBLIC SECTOR; REPETITIVE SEQUENCES, NUCLEIC ACID; RNA; SEQUENCE ANALYSIS, DNA; SPECIES SPECIFICITY;

EID: 2042437650     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35057062     Document Type: Article

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263. Human genes for U2 small nuclear RNA are tandemly repeated
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265. A survey on intron and exon lengths
266. Prediction of complete gene structures in human genomic DNA
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269. General splicing factor SF2/ASF promotes alternative splicing by binding to an exonic splicing enhancer
270. Polypurine sequences within a downstream exon function as a splicing enhancer
271. An intron splicing enhancer containing a G-rich repeat facilitates inclusion of a vertebrate micro-exon
272. Analysis of canonical and non-canonical splice sites in mammalian genomes
273. Evolutionary fates and origins of U12-type introns
274. Frequent alternative splicing of human genes
275. Alternative splicing of human genes: More the rule than the exception?
276. EST comparison indicates 38% of human mRNAs contain possible alternative splice forms
277. The gene guessing game
278. Researchers take a gamble on the human genome
279. How many genes in the human genome?
280. Gene index analysis of the human genome estimates approximately 120,000 genes
281. Estimate of human gene number provided by genome-wide analysis using Tetraodon nigroviridis DNA sequence
282. Genome sequence of the nematode C. elegans: A platform for investigating biology
283. Comparative genomics of the eukaryotes
284. Ancient conserved regions in new gene sequences and the protein databases
285. Functional genomic analysis of C. elegans chromosome 1 by systematic RNA interference
286. EST_GENOME: A program to align spliced DNA sequences to unspliced genomic DNA
287. A computer program for aligning a cDNA sequence with a genomic DNA sequence
288. Analysis of EST-driven gene annotation in human genomic sequence
289. PairWise and SearchWise: Finding the optimal alignment in a simultaneous comparison of a protein profile against all DNA translation frames
290. Gene recognition via spliced sequence alignment
291. A generalized hidden Markov model for the recognition of human genes in DNA
292. Genie - Gene finding in Drosophila melanogaster
293. The Gene-Finder computer tools for analysis of human and model organisms genome sequences
294. An assessment of gene prediction accuracy in large DNA sequences
295. Open annotation offers a democratic solution to genome sequencing
296. The Pfam protein families database
297. Using GeneWise in the Drosophila annotation experiment
298. Functional annotation of a full-length mouse cDNA collection
299. Small open reading frames: Beautiful needles in the haystack
300. Domains in proteins: Definitions, location, and structural principles
301. Evolution of domain families
302. The multiplicity of domains in proteins
303. Searching databases to find protein domain organization
304. Cancer and genomics
305. Learning about addiction from the human draft genome
306. Expressing the human genome
307. A genomic view of immunology
308. Evolutionary analyses of the human ganome
309. A genomic perspective on membrane compartment organization
310. Genomics the cytoskeleton and motility
311. Can sequencing shed light on cell cycling?
312. Keeping time with the human genome
313. Comparison of the complete protein sets of worm and yeast: Orthology and divergence
314. Origin of multicellular eukaryotes - Insights from proteome comparisons
315. PRINTS-S: The database formerly known as PRINTS
316. The PROSITE database, its status in 1999
317. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
318. No footprints of primordial introns in a eukaryotic genome
319. Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A
320. Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA
321. X-linked borderline mental retardation with prominent behavioral disturbance: Phenotype, genetic localization, and evidence for disturbed monoamine metabolism
322. Excess of high activity monoamine oxidase A gene promoter alleles in female patients with panic disorder
323. Identification of common molecular subsequences
324. A genomic perspective on protein families
325. Eukaryotic signalling domain homologues in archaea and bacteria. Ancient ancestry and horizontal gene transfer
326. Evolution of the rodent eosinophil-associated Rnase gene family by rapid gene sorting and positive selection
327. Ependymin, a brain extracellular glycoprotein, and CNS plasticity
328. SMART: A web-based tool for the study of genetically mobile domains
329. The impact of comparative genomics on our understanding of evolution
330. Members of the immunoglobulin superfamily in bacteria
331. Branchless encodes a Drosophila FGF homolog that controls tracheal cell migration and the pattern of branching
332. The molecular basis of lung morphogenesis
333. The human olfactory subgenome: From sequence to structure to evolution
334. The olfactory receptor gene family: Data mining, classification and nomenclature
335. Distribution of olfactory receptor genes in the human genome
336. Primate evolution of an olfactory receptor cluster: Diversification by gene conversion and recent emergence of a pseudogene
337. Dichotomy of single-nucleotide polymorphism haplotypes in olfactory receptor genes and pseudogenes
338. The syntenic relationship of the zebrafish and human genomes
339. Estimation of synteny conservation and genome compaction between pufferfish (Fugu) and human
340. Linkage of TATA-binding protein and proteasome subunit C5 genes in mice and humans reveals synteny conserved between mammals and invertebrates
341. Maps of linkage and synteny homologies between mouse and man
342. Lengths of chromosomal segments conserved since divergence of man and mouse
343. A genetic linkage map of the mouse: Current applications and future prospects
344. Human/mouse homology relationships
345. The lengths of undiscovered conserved segments in comparative maps
346. Comparative genome mapping in the sequence-based era: Early experience with human chromosome 7
347. Chromosome evolution: The junction of mammalian chromosomes in the formation of mouse chromosome 10
348. Mammalian phylogeny: Shaking the tree
349. Genome maps 10. Comparative genomics. Mammalian radiations. Wall chart
350. Toward a unified genetic map of higher plants, transcending the monocot-dicot divergence
351. Differentiation between natural and cultivated populations of Medicago sativa (Leguminosae) from Spain: Analysis with random amplified polymorphic DNA (RAPD) markers and comparison to allozymes
352. Molecular evidence for an ancient duplication of the entire yeast genome
353. Extensive duplication and reshuffling in the arabidopsis genome
354. Comparative genomics of plant chromosomes
355. The origins of genome duplications in Arabidopsis
356. Molecular phylogeny
357. A molecular evolutionary framework for eukaryotic model organisms
358. Gen(om)e duplications in the evolution of early vertebrates
359. Vertebrate evolution by interspecific hybridisation - Are we polyploid?
360. Eukaryote genome duplication - Where's the evidence?
361. Phylogenies of developmentally important proteins do not support the hypothesis of two rounds of genome duplication early in vertebrate history
362. Genetic dissection of complex traits
363. Genetic variability in the gene encoding calpain-10 is associated with type 2 diabetes mellitus
364. The diastrophic dysplasia gene encodes a novel sulfate transporter: Positional cloning by fine-structure linkage disequilibrium mapping
365. Global patterns of linkage disequilibrium at the CD4 locus and modern human origins
366. Haplotypes and linkage disequilibrium at the phenylalanine hydroxylase locus PAH, in a global representation of populations
367. Worldwide genetic analysis of the CFTR region
368. Extent and distribution of linkage disequilibrium in three genomic regions
369. Juxtaposed regions of extensive and minimal linkage disequilibrium in Xq25 and Xq28
370. SNPing away at complex diseases: Analysis of single-nucleotide polymorphisms around APOE in Alzheimer disease
371. Genetic epidemiology of single-nucleotide polymorphisms
372. The extent of linkage disequilibrium in four populations with distinct demographic histories
373. Sequence variation in the human angiotensin convening enzyme
374. Positional cloning moves from perditional to traditional
375. Positional cloning of the APECED gene
376. Mutations in PEX1 are the most common cause of peroxisome biogenesis disorders
377. Human PEX1 is mutated in complementation group 1 of the peroxisome biogenesis disorders
378. Pendred syndrome is caused by mutations in a putative sulphate transporter gene (PDS)
379. Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene
380. Nonsyndromic hearing impairment is associated with a mutation in DFNA5
381. Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease
382. Identification of the gene (SEDL) causing X-linked spondyloepiphyseal dysplasia tarda
383. Mutations in the CCN gene family member WISP3 cause progressive pseudorheumatoid dysplasia
384. Truncating mutations in CCM1, encoding KRIT1, cause hereditary cavernous angiomas
385. Mutations in the gene encoding KRIT1, a Krev-1/rapla binding protein, cause cerebral cavernous malformations (CCM1)
386. Mutations in COL11A2 cause non-syndromic hearing loss (DFNA13)
387. Limb-girdle muscular dystrophy type 2G is caused by mutations in the gene encoding the sarcomeric protein telethonin
388. Mutations in a new gene in Ellis-van Creveld syndrome and Weyers acrodental dysostosis
389. Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis
390. Mutations of SCN1A, encoding a neuronal sodium channel, in two families with GEFS+2
391. Identification of the alpha-aminoadipic semialdehyde synthase gene, which is defective in familial hyperlysinemia
392. N-myc downstream-regulated gene 1 is mutated in hereditary motor and sensory neuropathy-Lom
393. Genetic basis of total colourblindness among the Pingelapese islanders
394. Mutations in the CNGB3 gene encoding the beta-subunit of the cone photoreceptor cGMP-gated channel are responsible for achromatopsia (ACHM3) linked to chromosome 8q21
395. Gene encoding a new RING-B-box-coiled-coil protein is mutated in mulibrey nanism
396. A defect in harmonin, a PDZ domain-containing protein expressed in the inner ear sensory hair cells, underlies usher syndrome type 1C
397. A recessive contiguous gene deletion causing infantile hyperinsulinism, enteropathy and deafness identifies the usher type 1C gene
398. Mutations in MYH9 result in the May-Hegglin anomaly, and Fechtner and Sebastian syndromes
399. Mutation of MYH9, encoding non-muscle myosin heavy chain A, in May-Hegglin anomaly
400. Mutations of the gene encoding the protein kinase A type I-α regulatory subunit in patients with the Carney complex
401. Human nonsyndromic hereditary deafness DFNA17 is due to a mutation in non-muscle myosin MYH9
402. Large expansion of the ATTCT pentanucleotide repeat in spinocerebellar ataxia type 10
403. Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy
404. The complete form of X-linked congenital stationary night blindness is caused by mutations in a gene encoding a leucine-rich repeat protein
405. Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23
406. The gene encoding gigaxonin, a new member of the cytoskeletal BTB/kelch repeat family, is mutated in giant axonal neuropathy
407. Mutant WD-repeat protein in triple-A syndrome
408. Perlecan, the major proteoglycan of basement membranes, is altered in patients with Schwartz-Jampel syndrome (chondrodystrophic myotonia)
409. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
410. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
411. The therapeutic reactivation of fetal haemoglobin
412. Research & development. Basic science and pharmaceutical innovation
413. Drug discovery: A historical perspective
414. The 5-HT3B subunit is a major determinant of serotonin-receptor function
415. Characterization of the human cysteinyl leukotriene 2 receptor
416. BACE maps to chromosome 11 and a BACE homolog, BACE2, reside in the obligate Down Syndrome region of chromosome 21
417. BACE maps to chromosome 11 and a BACE homolog, BACE2, reside in the obligate Down Syndrome region of chromosome 21
418. The good taste of genomics
419. A family of candidate taste receptors in human and mouse
420. A novel family of mammalian taste receptors
421. T2Rs function as bitter taste receptors
422. Conserved non-coding sequences are reliable guides to regulatory elements
423. Sequence and comparative analysis of the mouse 1-megabase region orthologous to the human 11p15 imprinted domain
424. Shotgun sample sequence comparisons between mouse and human genomes
425. Public-private project to deliver mouse genome in 6 months
426. Human-mouse genome comparisons to locate regulatory sites
427. Embryonic epsilon and gamma globin genes of a prosimian primate (Galago crassicaudatus). Nucleotide and amino acid sequences, developmental regulation and phylogenetic footprints
428. Conservation of DNA regulatory motifs and discovery of new motifs in microbial genomes
429. Finding DNA regulatory motifs within unaligned noncoding sequences clustered by whole-genome mRNA quantitation
430. Biclustering of expression data
431. A computational analysis of whole-genome expression data reveals chromosomal domains of gene expression
432. Genomic imprinting in mammals: An interplay between chromatin and DNA methylation?
433. DNA methylation in health and disease
434. From genomics to epigenomics: A loftier view of life
435. Mapping a subtext in our genetic book
436. FPC: A system for building contigs from restriction fingerprinted clones
437. Approximate statistics of gapped alignments