Zinc Chelation by a Small-Molecule Adjuvant Potentiates Meropenem Activity in Vivo against NDM-1-Producing Klebsiella pneumoniae

ACS Infectious Diseases

Volumn 1, Issue 11, 2016, Pages 533-543

  Falconer, Shannon B ^a   Reid Yu, Sarah A ^a   King, Andrew M ^a   Gehrke, Sebastian S ^a   Wang, Wenliang ^a   Britten, James F ^b   Coombes, Brian K ^a   Wright, Gerard D ^a   Brown, Eric D ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

antibiotic adjuvant lactam resistance Klebsiella pneumoniae zinc chelator

Indexed keywords

MEROPENEM; ZINC;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL CELL; BACTERIAL LOAD; CHELATION; CONTROLLED STUDY; DRUG POTENTIATION; KLEBSIELLA PNEUMONIAE; KLEBSIELLA PNEUMONIAE INFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; ZINC CHELATION; ZINC HOMEOSTASIS;

EID: 84969263292     PISSN: None     EISSN: 23738227     Source Type: Journal    
DOI: 10.1021/acsinfecdis.5b00033     Document Type: Article

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