Pyridomycin bridges the NADH- and substrate-binding pockets of the enoyl reductase InhA.

Nature chemical biology

Volumn 10, Issue 2, 2014, Pages 96-98

  Hartkoorn, Ruben C ^a   Pojer, Florence ^a   Read, Jon A ^a   Gingell, Helen ^a   Neres, João ^a   Horlacher, Oliver P ^a   Altmann, Karl Heinz ^a   Cole, Stewart T ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; INHA PROTEIN, MYCOBACTERIUM; NICOTINAMIDE ADENINE DINUCLEOTIDE; OLIGOPEPTIDE; OXIDOREDUCTASE; PYRIDOMYCIN; TUBERCULOSTATIC AGENT;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; ENZYME SPECIFICITY; X RAY CRYSTALLOGRAPHY;

ANTITUBERCULAR AGENTS; BACTERIAL PROTEINS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; NAD; OLIGOPEPTIDES; OXIDOREDUCTASES; SUBSTRATE SPECIFICITY;

EID: 84897108482     PISSN: None     EISSN: 15524469     Source Type: None    
DOI: 10.1038/nchembio.1405     Document Type: Article

References (0)