The transcription inhibitor lipiarmycin blocks DNA fitting into the RNA polymerase catalytic site

EMBO Journal

Volumn 29, Issue 15, 2010, Pages 2527-2537

  Tupin, Audrey ^a   Gualtieri, Maxime ^a   Leonetti, Jean Paul ^a   Brodolin, Konstantin ^a  

^a University of Montpellier I and II   (France)

Author keywords

antibiotic resistance; lipiarmycin; RNA polymerase; sigma region 3.2; switch region

Indexed keywords

ANTIBIOTIC AGENT; BACTERIAL RNA; DNA; LIPIARMYCIN; RNA POLYMERASE; RNA POLYMERASE BETA SUBUNIT; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; CATALYSIS; DNA STRAND; DNA TEMPLATE; DRUG TARGETING; ISOMERIZATION; MELTING POINT; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN INTERACTION; RNA SYNTHESIS;

AMINOGLYCOSIDES; BASE SEQUENCE; CATALYTIC DOMAIN; DNA; DNA-DIRECTED RNA POLYMERASES; GENE DELETION; MODELS, MOLECULAR; NUCLEIC ACID DENATURATION; PROMOTER REGIONS, GENETIC; RNA; TRANSCRIPTION, GENETIC;

BACTERIA (MICROORGANISMS);

EID: 77955423906     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2010.135     Document Type: Article

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