메뉴 건너뛰기




Volumn 449, Issue 7164, 2007, Pages 804-810

The Human Microbiome Project

Author keywords

[No Author keywords available]

Indexed keywords

BIOME; GENETIC ANALYSIS; METABOLISM; PHYSIOLOGY; PROJECT ASSESSMENT;

EID: 35348968286     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature06244     Document Type: Review
Times cited : (4375)

References (54)
  • 1
    • 33744804299 scopus 로고    scopus 로고
    • Metagenomic analysis of the human distal gut microbiome
    • Gill, S. R. et al. Metagenomic analysis of the human distal gut microbiome. Science 312, 1355-1359 (2006).
    • (2006) Science , vol.312 , pp. 1355-1359
    • Gill, S.R.1
  • 4
    • 0021644847 scopus 로고
    • The productivity diversity relationship: Tilman's pattern reflected in rodent communities
    • Ambramsky, Z. & Rosenzweig, M. L. The productivity diversity relationship: Tilman's pattern reflected in rodent communities. Nature 309, 150-151 (1984).
    • (1984) Nature , vol.309 , pp. 150-151
    • Ambramsky, Z.1    Rosenzweig, M.L.2
  • 5
    • 23344442120 scopus 로고    scopus 로고
    • Obesity alters gut microbial ecology
    • Ley, R. E. et al. Obesity alters gut microbial ecology. Proc. Natl Acad. Sci. USA 102, 11070-11075 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 11070-11075
    • Ley, R.E.1
  • 6
    • 33749997498 scopus 로고    scopus 로고
    • Reciprocal gut microbiota transplants from zebrafish and mice to germ-free recipients reveal host habitat selection
    • Rawls, J. F., Mahowald, M. A., Ley, R. E. & Gordon, J. I. Reciprocal gut microbiota transplants from zebrafish and mice to germ-free recipients reveal host habitat selection. Cell 127, 423-433 (2006).
    • (2006) Cell , vol.127 , pp. 423-433
    • Rawls, J.F.1    Mahowald, M.A.2    Ley, R.E.3    Gordon, J.I.4
  • 7
    • 2542523843 scopus 로고    scopus 로고
    • ARB: A software environment for sequence data
    • Ludwig, W. et al. ARB: a software environment for sequence data. Nucleic Acids Res. 32, 1363-1371 (2004).
    • (2004) Nucleic Acids Res , vol.32 , pp. 1363-1371
    • Ludwig, W.1
  • 8
    • 13444304367 scopus 로고    scopus 로고
    • The Ribosomal Database Project (RDP-II): Sequences and tools for highthroughput rRNA analysis
    • Cole, J. R. et al. The Ribosomal Database Project (RDP-II): sequences and tools for highthroughput rRNA analysis. Nucleic Acids Res. 33, D294-D296 (2005).
    • (2005) Nucleic Acids Res , vol.33
    • Cole, J.R.1
  • 9
    • 15444362001 scopus 로고    scopus 로고
    • DOTUR, a computer program for defining operational taxonomic units and estimating species richness
    • Schloss, P. D. & Handelsman, J. DOTUR, a computer program for defining operational taxonomic units and estimating species richness. Appl. Environ. Microbiol. 71, 1501-1506 (2005).
    • (2005) Appl. Environ. Microbiol , vol.71 , pp. 1501-1506
    • Schloss, P.D.1    Handelsman, J.2
  • 10
    • 33747827586 scopus 로고    scopus 로고
    • NAST: A multiple sequence alignment server for comparative analysis of 16S rRNA genes
    • DeSantis, T. Z. et al. NAST: a multiple sequence alignment server for comparative analysis of 16S rRNA genes. Nucleic Acids Res. 34, W394-W399 (2006).
    • (2006) Nucleic Acids Res , vol.34
    • DeSantis, T.Z.1
  • 11
    • 33748713890 scopus 로고    scopus 로고
    • UniFrac - an online tool for comparing microbial community diversity in a phylogenetic context
    • Lozupone, C., Hamady, M. & Knight, R. UniFrac - an online tool for comparing microbial community diversity in a phylogenetic context. BMC Bioinformatics 7, 371 (2006).
    • (2006) BMC Bioinformatics , vol.7 , pp. 371
    • Lozupone, C.1    Hamady, M.2    Knight, R.3
  • 12
    • 33847305053 scopus 로고    scopus 로고
    • Molecular analysis of human forearm superficial skin bacterial biota
    • Gao, Z. et al. Molecular analysis of human forearm superficial skin bacterial biota. Proc. Natl Acad. Sci. USA 104, 2927-2932 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 2927-2932
    • Gao, Z.1
  • 13
    • 1642488364 scopus 로고    scopus 로고
    • Bacterial biota in the human distal esophagus
    • Pei, Z. et al. Bacterial biota in the human distal esophagus. Proc. Natl Acad. Sci. USA 101, 4250-4255 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 4250-4255
    • Pei, Z.1
  • 14
    • 31444449652 scopus 로고    scopus 로고
    • Molecular analysis of the bacterial microbiota in the human stomach
    • Bik, E. M. et al. Molecular analysis of the bacterial microbiota in the human stomach. Proc. Natl Acad. Sci. USA 103, 732-737 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 732-737
    • Bik, E.M.1
  • 15
    • 20544444045 scopus 로고    scopus 로고
    • Diversity of the human intestinal microbial flora
    • Eckburg, P. B. et al. Diversity of the human intestinal microbial flora. Science 308, 1635-1638 (2005).
    • (2005) Science , vol.308 , pp. 1635-1638
    • Eckburg, P.B.1
  • 16
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: Human gut microbes associated with obesity
    • Ley, R. E., Turnbaugh, P. J., Klein, S. & Gordon, J. I. Microbial ecology: Human gut microbes associated with obesity. Nature 444, 1022-1023 (2006).
    • (2006) Nature , vol.444 , pp. 1022-1023
    • Ley, R.E.1    Turnbaugh, P.J.2    Klein, S.3    Gordon, J.I.4
  • 17
    • 20344371715 scopus 로고    scopus 로고
    • Microbes on the human vaginal epithelium
    • Hyman, R. W. et al. Microbes on the human vaginal epithelium. Proc. Natl Acad. Sci. USA 102, 7952-7957 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 7952-7957
    • Hyman, R.W.1
  • 18
    • 33745080242 scopus 로고    scopus 로고
    • Neutral theory and the evolution of ecological equivalence
    • Hubbell, S. P. Neutral theory and the evolution of ecological equivalence. Ecology 87, 1387-1398 (2006).
    • (2006) Ecology , vol.87 , pp. 1387-1398
    • Hubbell, S.P.1
  • 19
    • 33845874101 scopus 로고    scopus 로고
    • An obesity-associated gut microbiome with increased capacity for energy harvest
    • Turnbaugh, P. J. et al. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 444, 1027-1031 (2006).
    • (2006) Nature , vol.444 , pp. 1027-1031
    • Turnbaugh, P.J.1
  • 20
    • 20244376755 scopus 로고    scopus 로고
    • Comparative metagenomics of microbial communities
    • Tringe, S. G. et al. Comparative metagenomics of microbial communities. Science 308, 554-557 (2005).
    • (2005) Science , vol.308 , pp. 554-557
    • Tringe, S.G.1
  • 21
    • 11144354360 scopus 로고    scopus 로고
    • Environmental genome shotgun sequencing of the Sargasso Sea
    • Venter, J. C. et al. Environmental genome shotgun sequencing of the Sargasso Sea. Science 304, 66-74 (2004).
    • (2004) Science , vol.304 , pp. 66-74
    • Venter, J.C.1
  • 23
    • 84945510083 scopus 로고    scopus 로고
    • Gordon, J. I. et al. Extending our view of self: the Human Gut Microbiome Initiative (HGMI). National Human Genome Research Institute 〈http://www.genome.gov/Pages/Research/Sequencing/SeqProposals/HGMISeq.pdf (2005).
    • Gordon, J. I. et al. Extending our view of self: the Human Gut Microbiome Initiative (HGMI). National Human Genome Research Institute 〈http://www.genome.gov/Pages/Research/Sequencing/SeqProposals/HGMISeq.pdf (2005).
  • 24
    • 34447516925 scopus 로고    scopus 로고
    • Evolution of symbiotic bacteria in the distal human intestine
    • Xu, J. et al. Evolution of symbiotic bacteria in the distal human intestine. PLoS Biol. 5, e156 (2007).
    • (2007) PLoS Biol , vol.5
    • Xu, J.1
  • 25
    • 34249701816 scopus 로고    scopus 로고
    • Targeted access to the genomes of low abundance organisms in complex microbial communities
    • Podar, M. et al. Targeted access to the genomes of low abundance organisms in complex microbial communities. Appl. Environ. Microbiol. 73, 3205-3214 (2007).
    • (2007) Appl. Environ. Microbiol , vol.73 , pp. 3205-3214
    • Podar, M.1
  • 26
    • 0037180507 scopus 로고    scopus 로고
    • Cultivating the uncultured
    • Zengler, K. et al. Cultivating the uncultured. Proc. Natl Acad. Sci. USA 99, 15681-15686 (2002).
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 15681-15686
    • Zengler, K.1
  • 27
    • 13244253777 scopus 로고    scopus 로고
    • TETRA: A web-service and stand-alone program for the analysis and comparison of tetranucleotide usage patterns in DNA sequences
    • Teeling, H. et al. TETRA: a web-service and stand-alone program for the analysis and comparison of tetranucleotide usage patterns in DNA sequences. BMC Bioinformatics 5, 163 (2004).
    • (2004) BMC Bioinformatics , vol.5 , pp. 163
    • Teeling, H.1
  • 28
    • 33845957530 scopus 로고    scopus 로고
    • Accurate phylogenetic classification of variable-length DNA fragments
    • McHardy, A. C. et al. Accurate phylogenetic classification of variable-length DNA fragments. Nature Methods 4, 63-72 (2007).
    • (2007) Nature Methods , vol.4 , pp. 63-72
    • McHardy, A.C.1
  • 29
    • 33847291893 scopus 로고    scopus 로고
    • Quantitative phylogenetic assessment of microbial communities in diverse environments
    • von Mering, C. et al. Quantitative phylogenetic assessment of microbial communities in diverse environments. Science 315, 1126-1130 (2007).
    • (2007) Science , vol.315 , pp. 1126-1130
    • von Mering, C.1
  • 30
    • 79959524146 scopus 로고    scopus 로고
    • A haplotype map of the human genome
    • International HapMap Consortium
    • International HapMap Consortium. A haplotype map of the human genome. Nature 437, 1299-1320 (2005).
    • (2005) Nature , vol.437 , pp. 1299-1320
  • 31
    • 29144464937 scopus 로고    scopus 로고
    • UniFrac: A new phylogenetic method for comparing microbial communities
    • Lozupone, C. & Knight, R. UniFrac: a new phylogenetic method for comparing microbial communities. Appl. Environ. Microbiol. 71, 8228-8235 (2005).
    • (2005) Appl. Environ. Microbiol , vol.71 , pp. 8228-8235
    • Lozupone, C.1    Knight, R.2
  • 32
    • 33947269742 scopus 로고    scopus 로고
    • Quantitative and qualitative β diversity measures lead to different insights into factors that structure microbial communities
    • Lozupone, C. A., Hamady, M., Kelley, S. T. & Knight, R. Quantitative and qualitative β diversity measures lead to different insights into factors that structure microbial communities. Appl. Environ. Microbiol. 73, 1576-1585 (2007).
    • (2007) Appl. Environ. Microbiol , vol.73 , pp. 1576-1585
    • Lozupone, C.A.1    Hamady, M.2    Kelley, S.T.3    Knight, R.4
  • 33
    • 0035656126 scopus 로고    scopus 로고
    • Development and evaluation of functional gene arrays for detection of selected genes in the environment
    • Wu, L. et al. Development and evaluation of functional gene arrays for detection of selected genes in the environment. Appl. Environ. Microbiol. 67, 5780-5790 (2001).
    • (2001) Appl. Environ. Microbiol , vol.67 , pp. 5780-5790
    • Wu, L.1
  • 34
    • 33748707177 scopus 로고    scopus 로고
    • Microarray application in microbial ecology research
    • Gentry, T. J. et al. Microarray application in microbial ecology research. Microb. Ecol. 52, 159-175 (2006).
    • (2006) Microb. Ecol , vol.52 , pp. 159-175
    • Gentry, T.J.1
  • 35
    • 33846435742 scopus 로고    scopus 로고
    • Microarray-based analysis of microbial community RNAs by whole-community RNA amplification
    • Gao, H. et al. Microarray-based analysis of microbial community RNAs by whole-community RNA amplification. Appl. Environ. Microbiol. 73, 563-571 (2007).
    • (2007) Appl. Environ. Microbiol , vol.73 , pp. 563-571
    • Gao, H.1
  • 36
    • 22144493007 scopus 로고    scopus 로고
    • Analysis of microbial gene transcripts in environmental samples
    • Poretsky, R. S. et al. Analysis of microbial gene transcripts in environmental samples. Appl. Environ. Microbiol. 71, 4121-4126 (2005).
    • (2005) Appl. Environ. Microbiol , vol.71 , pp. 4121-4126
    • Poretsky, R.S.1
  • 37
    • 33644868996 scopus 로고    scopus 로고
    • Identification of eukaryotic open reading frames in metagenomic cDNA libraries made from environmental samples
    • Grant, S. et al. Identification of eukaryotic open reading frames in metagenomic cDNA libraries made from environmental samples. Appl. Environ. Microbiol. 72, 135-143 (2006).
    • (2006) Appl. Environ. Microbiol , vol.72 , pp. 135-143
    • Grant, S.1
  • 38
    • 21344465408 scopus 로고    scopus 로고
    • Community proteomics of a natural microbial biofilm
    • Ram, R. J. et al. Community proteomics of a natural microbial biofilm. Science 308, 1915-1920 (2005).
    • (2005) Science , vol.308 , pp. 1915-1920
    • Ram, R.J.1
  • 39
    • 33846088138 scopus 로고    scopus 로고
    • HMDB: The human metabolome database
    • Wishart, D. S. et al. HMDB: the human metabolome database. Nucleic Acids Res. 35, D521-D526 (2007).
    • (2007) Nucleic Acids Res , vol.35
    • Wishart, D.S.1
  • 41
    • 9444225935 scopus 로고    scopus 로고
    • Java Treeview - extensible visualization of microarray data
    • Saldanha, A. J. Java Treeview - extensible visualization of microarray data. Bioinformatics 20, 3246-3248 (2004).
    • (2004) Bioinformatics , vol.20 , pp. 3246-3248
    • Saldanha, A.J.1
  • 42
    • 8144226856 scopus 로고    scopus 로고
    • The gut microbiota as an environmental factor that regulates fat storage
    • Backhed, F. et al. The gut microbiota as an environmental factor that regulates fat storage. Proc. Natl Acad. Sci. USA 101, 15718-15723 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 15718-15723
    • Backhed, F.1
  • 44
    • 34249036137 scopus 로고    scopus 로고
    • A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model
    • doi:10.1038/msb4100153
    • Martin, F. J. et al. A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model. Mol. Syst. Biol. 3, doi:10.1038/msb4100153 (2007).
    • (2007) Mol. Syst. Biol , vol.3
    • Martin, F.J.1
  • 45
    • 0034821010 scopus 로고    scopus 로고
    • Rapid reversal of hyperoxaluria in a rat model after probiotic administration of Oxalobacter formigenes
    • Sidhu, H., Allison, M. J., Chow, J. M., Clark, A. & Peck, A. B. Rapid reversal of hyperoxaluria in a rat model after probiotic administration of Oxalobacter formigenes. J. Urol. 166, 1487-1491 (2001).
    • (2001) J. Urol , vol.166 , pp. 1487-1491
    • Sidhu, H.1    Allison, M.J.2    Chow, J.M.3    Clark, A.4    Peck, A.B.5
  • 46
    • 0842304289 scopus 로고    scopus 로고
    • Bacteria-induced intestinal cancer in mice with disrupted Gpx1 and Gpx2 genes
    • Chu, F. F. et al. Bacteria-induced intestinal cancer in mice with disrupted Gpx1 and Gpx2 genes. Cancer Res. 64, 962-968 (2004).
    • (2004) Cancer Res , vol.64 , pp. 962-968
    • Chu, F.F.1
  • 47
    • 11844279745 scopus 로고    scopus 로고
    • Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury
    • Pull, S. L., Doherty, J. M., Mills, J. C., Gordon, J. I. & Stappenbeck, T. S. Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury. Proc. Natl Acad. Sci. USA 102, 99-104 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 99-104
    • Pull, S.L.1    Doherty, J.M.2    Mills, J.C.3    Gordon, J.I.4    Stappenbeck, T.S.5
  • 48
    • 0037340434 scopus 로고    scopus 로고
    • Angiogenins: A new class of microbicidal proteins involved in innate immunity
    • Hooper, L. V., Stappenbeck, T. S., Hong, C. V. & Gordon, J. I. Angiogenins: a new class of microbicidal proteins involved in innate immunity. Nature Immunol. 4, 269-273 (2003).
    • (2003) Nature Immunol , vol.4 , pp. 269-273
    • Hooper, L.V.1    Stappenbeck, T.S.2    Hong, C.V.3    Gordon, J.I.4
  • 49
    • 22144490199 scopus 로고    scopus 로고
    • An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system
    • Mazmanian, S. K., Liu, C. H., Tzianabos, A. O. & Kasper, D. L. An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system. Cell 122, 107-118 (2005).
    • (2005) Cell , vol.122 , pp. 107-118
    • Mazmanian, S.K.1    Liu, C.H.2    Tzianabos, A.O.3    Kasper, D.L.4
  • 50
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Wellcome Trust Case Control Consortium
    • Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447, 661-678 (2007).
    • (2007) Nature , vol.447 , pp. 661-678
  • 51
    • 33748039462 scopus 로고    scopus 로고
    • Symbiotic bacteria direct expression of an intestinal bactericidal lectin
    • Cash, H. L., Whitham, C. V., Behrendt, C. L. & Hooper, L. V. Symbiotic bacteria direct expression of an intestinal bactericidal lectin. Science 313, 1126-1130 (2006).
    • (2006) Science , vol.313 , pp. 1126-1130
    • Cash, H.L.1    Whitham, C.V.2    Behrendt, C.L.3    Hooper, L.V.4
  • 52
    • 0037136585 scopus 로고    scopus 로고
    • Environmental exposure to endotoxin and its relation to asthma in school-age children
    • Braun-Fahrlander, C. et al. Environmental exposure to endotoxin and its relation to asthma in school-age children. N. Engl. J. Med. 347, 869-877 (2002).
    • (2002) N. Engl. J. Med , vol.347 , pp. 869-877
    • Braun-Fahrlander, C.1
  • 53
    • 34250861286 scopus 로고    scopus 로고
    • Increased risk of childhood asthma from antibiotic use in early life
    • Kozyrskyj, A. L., Ernst, P. & Becker, A. B. Increased risk of childhood asthma from antibiotic use in early life. Chest 131, 1753-1759 (2007).
    • (2007) Chest , vol.131 , pp. 1753-1759
    • Kozyrskyj, A.L.1    Ernst, P.2    Becker, A.B.3
  • 54
    • 0020068173 scopus 로고
    • Oxygen consumption and thyroid hormones in germfree mice fed glucose-amino acid liquid diet
    • Wostmann, B. S., Bruckner-Kardoss, E. & Pleasants, J. R. Oxygen consumption and thyroid hormones in germfree mice fed glucose-amino acid liquid diet. J. Nutr. 112, 552-559 (1982).
    • (1982) J. Nutr , vol.112 , pp. 552-559
    • Wostmann, B.S.1    Bruckner-Kardoss, E.2    Pleasants, J.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.