Spirohexalines, new inhibitors of bacterial undecaprenyl pyrophosphate synthase, produced by Penicillium brasilianum FKI-3368

Journal of Antibiotics

Volumn 66, Issue 1, 2013, Pages 37-41

  Inokoshi, Junji ^a   Nakamura, Yuichiro ^a   Hongbin, Zhang ^a   Uchida, Ryuji ^a   Nonaka, Ken Ichi ^a   Masuma, Rokuro ^a   Tomoda, Hiroshi ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

cis prenyltransferase; methicillin resistant Staphylococcus aureus; spirohexaline; undecaprenyl pyrophosphate

Indexed keywords

ACETIC ACID ETHYL ESTER; ANTIBIOTIC AGENT; BACTERIAL ENZYME; CARBON 13; DIMETHYLALLYLTRANSFERASE; ENZYME INHIBITOR; HEXACYCLINE; SPIROHEXALINE; UNCLASSIFIED DRUG; UNDECAPRENYL PYROPHOSPHATE SYNTHASE; VIRIDICATUMTOXIN;

ANTIMICROBIAL ACTIVITY; ARTICLE; CHEMICAL STRUCTURE; COLUMN CHROMATOGRAPHY; DNA SEQUENCE; DRUG PURIFICATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; FERMENTATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC 50; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; PENICILLIUM; PENICILLIUM BRASILIANUM; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STAPHYLOCOCCUS AUREUS; VANCOMYCIN RESISTANT ENTEROCOCCUS;

ALKYL AND ARYL TRANSFERASES; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENZYME INHIBITORS; MYCOTOXINS; PENICILLIUM; SPIRO COMPOUNDS;

EID: 84872839728     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2012.83     Document Type: Article

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