Inhibition of peptide bond formation by pleuromutilins: The structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin

Molecular Microbiology

Volumn 54, Issue 5, 2004, Pages 1287-1294

  Schlünzen, Frank ^a   Pyetan, Erez ^b,c   Fucini, Paola ^a   Yonath, Ada ^b,c   Harms, Jörg M ^b  

^a MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^b MAX PLANCK UNIT FOR STRUCTURAL MOLECULAR BIOLOGY   (Germany)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CHLORAMPHENICOL; CLINDAMYCIN; MIKAMYCIN B; PEPTIDYLTRANSFERASE; PLEUROMUTILIN; QUINUPRISTIN; RIBOSOME PROTEIN; RNA 23S; TIAMULIN;

ANTIMICROBIAL ACTIVITY; ARTICLE; CHEMICAL BOND; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DEINOCOCCUS RADIODURANS; DRUG BINDING SITE; DRUG MECHANISM; HYDROPHOBICITY; NONHUMAN; PEPTIDE BOND; PRIORITY JOURNAL; RIBOSOME SUBUNIT; RNA SEQUENCE; X RAY DIFFRACTION;

CRYSTALLOGRAPHY, X-RAY; DEINOCOCCUS; DITERPENES; MODELS, MOLECULAR; PEPTIDYL TRANSFERASES; PROTEIN CONFORMATION; PROTEIN SYNTHESIS INHIBITORS; RIBOSOMES; RNA, RIBOSOMAL, 23S;

DEINOCOCCUS RADIODURANS; POSIBACTERIA;

EID: 9644281855     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2004.04346.x     Document Type: Article

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