An automated Genomes-to-Natural Products platform (GNP) for the discovery of modular natural products

Nature Communications

Volumn 6, Issue , 2015, Pages

  Johnston, Chad W ^a   Skinnider, Michael A ^a   Wyatt, Morgan A ^a   Li, Xiang ^a   Ranieri, Michael R M ^a   Yang, Lian ^b   Zechel, David L ^c   Ma, Bin ^b   Magarvey, Nathan A ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF WATERLOO   (Canada)

^c QUEEN S UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYSUGAR; DEPSIPEPTIDE; GLYCOSYLATED PROTEIN; NATURAL PRODUCT; NONRIBOSOMAL PEPTIDE SYNTHETASE; POLYKETIDE; THANAMYCIN; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; BIOLOGICAL PRODUCT; LIPOPEPTIDE; PEPTIDE;

BACTERIUM; GENETIC ANALYSIS; GENOMICS; PEPTIDE; PROTEIN;

ACIDOVORAX; ARTICLE; BACTERIAL GENOME; BIOENGINEERING; COMBINATORIAL LIBRARY; CONTROLLED STUDY; GENE CLUSTER; LIQUID CHROMATOGRAPHY; NONHUMAN; TANDEM MASS SPECTROMETRY; VARIOVORAX; CHEMISTRY; COMAMONADACEAE; DRUG DEVELOPMENT; GLYCOSYLATION; HIGH THROUGHPUT SCREENING; PROCEDURES; SOFTWARE;

BACTERIA (MICROORGANISMS);

BACTERIAL PROTEINS; BIOLOGICAL PRODUCTS; COMAMONADACEAE; DRUG DISCOVERY; GENOME, BACTERIAL; GLYCOSYLATION; HIGH-THROUGHPUT SCREENING ASSAYS; LIPOPEPTIDES; PEPTIDES; POLYKETIDES; SOFTWARE;

EID: 84942761231     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms9421     Document Type: Article

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