Structure-Based Design and Biological Evaluation of Triphenyl Scaffold-Based Hybrid Compounds as Hydrolytically Stable Modulators of a LuxR-Type Quorum Sensing Receptor

ACS Infectious Diseases

Volumn 2, Issue 1, 2016, Pages 32-38

  O'Reilly, Matthew C ^a   Blackwell, Helen E ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

anti infectives; LasR receptor; Pseudomonas aeruginosa; quorum sensing; small molecule probes; virulence

Indexed keywords

ANTIBIOTIC AGENT; BENZENE DERIVATIVE; LASR RECEPTOR AGONIST; RECEPTOR; RECEPTOR BLOCKING AGENT; TRANSCRIPTION FACTOR LUXR; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG DESIGN; DRUG EFFICACY; DRUG POTENCY; DRUG STABILITY; NONHUMAN; PH; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; STRUCTURE ACTIVITY RELATION;

EID: 84969141520     PISSN: None     EISSN: 23738227     Source Type: Journal    
DOI: 10.1021/acsinfecdis.5b00112     Document Type: Article

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