Abyssomicin C - A polycyclic antibiotic from a marine Verrucosispora strain as an inhibitor of the p-aminobenzoic acid/tetrahydrofolate biosynthesis pathway

Angewandte Chemie - International Edition

Volumn 43, Issue 19, 2004, Pages 2574-2576

  Bister, Bojan ^a   Bischoff, Daniel ^a   Ströbele, Markus ^a   Riedlinger, Julia ^a   Reicke, Andreas ^a   Wolter, Falko ^a   Bull, Alan T ^b   Zähner, Hans ^c   Fiedler, Hans Peter ^a   Süssmuth, Roderich D ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF KENT   (United Kingdom)

^c NONE   (Switzerland)

Author keywords

Antibiotics; Metabolism; Michael addition; Natural products

Indexed keywords

ADDITION REACTIONS; BIOSYNTHESIS; ENZYMES; MARINE BIOLOGY; ORGANIC ACIDS;

IRREVERSIBLE TRAPPING; MICHAEL ADDITION; OCEAN FLOOR SEDIMENTS;

ANTIBIOTICS;

4 AMINOBENZOIC ACID; ABYSSOMICIN C; ANTIBIOTIC AGENT; TETRAHYDROFOLIC ACID; UNCLASSIFIED DRUG;

ACTINOMYCETES; ARTICLE; DRUG ACTIVITY; DRUG MECHANISM; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; INHIBITION KINETICS; MICHAEL ADDITION; NONHUMAN; SEDIMENT; VERRUCOSISPORA;

EID: 4544291065     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200353160     Document Type: Article

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