Beta-lactam antibiotics induce a lethal malfunctioning of the bacterial cell wall synthesis machinery

Cell

Volumn 159, Issue 6, 2014, Pages 1300-1311

  Cho, Hongbaek ^a   Uehara, Tsuyoshi ^a,b   Bernhardt, Thomas G ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAM ANTIBIOTIC; CEFALEXIN; FTSZ PROTEIN; MECILLINAM; PENICILLIN BINDING PROTEIN; ANTIINFECTIVE AGENT; BETA LACTAM; GLYCOSIDASE; PEPTIDOGLYCAN;

ARTICLE; BACTERIAL CELL WALL; BACTERIAL GROWTH; BACTERIAL STRAIN; CELL DEATH; CONTROLLED STUDY; CROSS LINKING; CYTOPLASM; DOWN REGULATION; DRUG SYNTHESIS; ESCHERICHIA COLI; GENETIC ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; QUALITY CONTROL; ANTAGONISTS AND INHIBITORS; CELL WALL; CYTOLOGY; DRUG EFFECTS; ENZYMOLOGY; METABOLISM;

BACTERIA (MICROORGANISMS);

AMDINOCILLIN; ANTI-BACTERIAL AGENTS; BETA-LACTAMS; CELL WALL; ESCHERICHIA COLI; GLYCOSIDE HYDROLASES; PENICILLIN-BINDING PROTEINS; PEPTIDOGLYCAN;

EID: 84923115231     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2014.11.017     Document Type: Article

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