The antibiotic CJ-15,801 is an antimetabolite that hijacks and then inhibits CoA biosynthesis

Chemistry and Biology

Volumn 19, Issue 5, 2012, Pages 559-571

  Van Der Westhuyzen, Renier ^a   Hammons, Justin C ^b   Meier, Jordan L ^b   Dahesh, Samira ^c   Moolman, Wessel J A ^a   Pelly, Stephen C ^a   Nizet, Victor ^c   Burkart, Michael D ^b   Strauss, Erick ^a  

^a STELLENBOSCH UNIVERSITY   (South Africa)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ANTIMETABOLITE; CJ 15,801; COENZYME A; PANTOTHENATE KINASE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC SENSITIVITY; ARTICLE; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; DRUG TRANSFORMATION; ENZYME INHIBITION; IC 50; NONHUMAN; STAPHYLOCOCCUS AUREUS;

ANTI-BACTERIAL AGENTS; ANTIMETABOLITES; COENZYME A; HUMANS; PANTOTHENIC ACID; SIGNAL TRANSDUCTION; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

STAPHYLOCOCCUS AUREUS;

EID: 84861631111     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2012.03.013     Document Type: Article

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