Probing the role of the vancomycin E-ring aryl chloride: Selective divergent synthesis and evaluation of alternatively substituted E-ring analogues

Journal of Medicinal Chemistry

Volumn 56, Issue 10, 2013, Pages 4116-4124

  Pinchman, Joseph R ^a   Boger, Dale L ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGLYCONE; TEICOPLANIN; TEICOPLANIN AGLYCONE; UNCLASSIFIED DRUG; VANCOMYCIN; VANCOMYCIN AGLYCONE;

ALCALIGENES FAECALIS; ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; DRUG SUBSTITUTION; DRUG SYNTHESIS; ELECTRONICS; ENTEROCOCCUS FAECALIS; HYDROPHOBICITY; METHYLATION; RING OPENING; STAPHYLOCOCCUS AUREUS; SUBSTITUTION REACTION;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BORON; CHLORIDES; ENTEROCOCCUS FAECALIS; INDICATORS AND REAGENTS; LIGANDS; MICROBIAL SENSITIVITY TESTS; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP; VANCOMYCIN; VANCOMYCIN RESISTANCE;

EID: 84878074276     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm4004494     Document Type: Article

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