The functional neurophysiology of the amyloid precursor protein (APP) processing pathway

Neuropharmacology

Volumn 59, Issue 4-5, 2010, Pages 243-267

  Randall, A D ^a   Witton, J ^a   Booth, C ^a   Hynes Allen, A ^a   Brown, J T ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Alzheimer's disease; Epilepsy; Excitability; Ion channels; Long term potentiation; Synapse; Synaptic plasticity

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; ALPHA SECRETASE; AMPA RECEPTOR; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID BETA PROTEIN[12-28]; AMYLOID BETA PROTEIN[25-35]; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; BETA SECRETASE 1; BUNGAROTOXIN RECEPTOR; CALCIUM CHANNEL L TYPE; CALCIUM ION; CENTRAL NERVOUS SYSTEM AGENTS; GAMMA SECRETASE; IMMUNOMODULATING AGENT; ION CHANNEL; MEMANTINE; MRK 560; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; POTASSIUM CHANNEL; PRESENILIN; PRION PROTEIN; RYANODINE RECEPTOR; SODIUM CHANNEL; SULFONAMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL;

ALZHEIMER DISEASE; BRAIN FUNCTION; CALCIUM HOMEOSTASIS; CELL MEMBRANE; CENTRAL NERVOUS SYSTEM DISEASE; CENTRAL NERVOUS SYSTEM FUNCTION; CHANNEL GATING; CLINICAL TRIAL; COGNITIVE DEFECT; ELECTROENCEPHALOGRAM; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HIPPOCAMPUS; HUMAN; LONG TERM DEPRESSION; LONG TERM POTENTIATION; MILD COGNITIVE IMPAIRMENT; MOLECULAR BIOLOGY; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NERVE DEGENERATION; NERVE EXCITABILITY; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NEUROLOGIC DISEASE; NEUROMODULATION; NEUROPHYSIOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; REVIEW; SENILE PLAQUE; SYNAPTIC INHIBITION; SYNAPTIC TRANSMISSION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; HUMANS; NEURAL PATHWAYS; NEURONAL PLASTICITY; SIGNAL TRANSDUCTION; SYNAPSES;

EID: 77955089126     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2010.02.011     Document Type: Review

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