Alzheimer β-amyloid blocks epileptiform activity in hippocampal neurons

Molecular and Cellular Neuroscience

Volumn 41, Issue 4, 2009, Pages 420-428

  Sepúlveda, Fernando J ^a   Opazo, Carlos ^a   Aguayo, Luis G ^a  

^a UNIVERSITY OF CONCEPCIÓN   (Chile)

Author keywords

A Aggregates; Amyloid beta; Anti homeostatic plasticity; Neurodegeneration; Synaptotoxicity

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; BICUCULLINE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; LUCIFERASE;

ALZHEIMER DISEASE; AMPLITUDE MODULATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; EPILEPTIC DISCHARGE; FEMALE; HIPPOCAMPUS; IMMUNOCYTOCHEMISTRY; IMMUNOPRECIPITATION; NERVE CELL CULTURE; NERVE CELL PLASTICITY; NONHUMAN; PATCH CLAMP; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR BLOCKING; SYNAPTIC TRANSMISSION; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING;

6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; AMYLOID BETA-PROTEIN; ANALYSIS OF VARIANCE; ANIMALS; BICUCULLINE; BIOPHYSICS; CALCIUM; CELL SURVIVAL; CREB-BINDING PROTEIN; ELECTRIC STIMULATION; EMBRYO, MAMMALIAN; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; GABA ANTAGONISTS; HIPPOCAMPUS; IMMUNOPRECIPITATION; MEMBRANE GLYCOPROTEINS; MICROSCOPY, ELECTRON, TRANSMISSION; MICROTUBULE-ASSOCIATED PROTEINS; NERVE TISSUE PROTEINS; NEURONS; PATCH-CLAMP TECHNIQUES; PEPTIDE FRAGMENTS; PREGNANCY; RATS; SODIUM CHANNEL BLOCKERS; SYNAPTIC TRANSMISSION; TETRODOTOXIN; TIME FACTORS; TRANSFECTION;

EID: 67449102266     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2009.04.012     Document Type: Article

References (37)

1. Aguayo, L.G., Parodi, J., Sepúlveda, F.J., Roa, J., Opazo, C., 2008. Inhibitory Effects of Aβ Aggregates on Synaptic Transmission in Hippocampal Neurons. Chapter 3. Neurodegenerative Diseases: From Molecular Concepts to Therapeutic Targets. Nova Science Publishers Inc.
2. Amatniek J.C., Hauser W.A., DelCastillo-Castaneda C., Jacobs D.M., Marder K., Bell K., Albert M., Brandt J., and Stern Y. Incidence and predictors of seizures in patients with Alzheimer's disease. Epilepsia 47 (2006) 867-872
3. Anderson A.E., Hrachovy R.A., Antalffy B.A., Armstrong D.L., and Swann J.W. A chronic focal epilepsy with mossy fiber sprouting follows recurrent seizures induced by intrahippocampal tetanus toxin injection in infant rats. Neuroscience 92 (1999) 73-82
4. Arnold F.J., Hofmann F., Bengtson C.P., Wittmann M., Vanhoutte P., and Bading H. Microelectrode array recordings of cultured hippocampal networks reveal a simple model for transcription and protein synthesis-dependent plasticity. J. Physiol. 564 (2005) 3-19
5. Ashe K.H. Synaptic structure and function in transgenic APP mice. Ann. N.Y. Acad. Sci. 924 (2000) 39-41
6. Braak H., and Braak E. Evolution of the neuropathology of Alzheimer's disease. Acta Neurol. Scand., Suppl. 165 (1996) 3-12
7. Bito H., and Takemoto-Kimura S. Ca(2+)/CREB/CBP-dependent gene regulation: a shared mechanism critical in long-term synaptic plasticity and neuronal survival. Cell Calcium 34 (2003) 425-430
8. Carrasco M.A., Castro P.A., Sepulveda F.J., Cuevas M., Tapia J.C., Izaurieta P., van Zundert B., and Aguayo L.G. Anti-homeostatic synaptic plasticity of glycine receptor function after chronic strychnine in developing cultured mouse spinal neurons. J. Neurochem. 100 (2007) 1143-1154
9. Dash P.K., Hochner B., and Kandel E.R. Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation. Nature 345 (1990) 718-721
10. Deisseroth K., Bito H., and Tsien R.W. Signaling from synapse to nucleus: postsynaptic CREB phosphorylation during multiple forms of hippocampal synaptic plasticity. Neuron 16 (1996) 89-101
11. Garrido J.L., Godoy J.A., Alvarez A., Bronfman M., and Inestrosa N.C. Protein kinase C inhibits amyloid beta peptide neurotoxicity by acting on members of the Wnt pathway. Faseb J. 16 (2002) 1982-1984
12. Grace E.A., Rabiner C.A., and Busciglio J. Characterization of neuronal dystrophy induced by fibrillar amyloid beta: implications for Alzheimer's disease. Neuroscience 114 (2002) 265-273
13. Gu X., Olson E.C., and Spitzer N.C. Spontaneous neuronal calcium spikes and waves during early differentiation. J. Neurosci. 14 (1994) 6325-6335
14. Hardy J. Amyloid, the presenilins and Alzheimer's disease. Trends Neurosci. 20 (1997) 154-159
15. Haass C., and Selkoe D.J. Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. Nat. Rev., Mol. Cell. Biol. 8 (2007) 101-112
16. Hsia A.Y., Masliah E., McConlogue L., Yu G.Q., Tatsuno G., Hu K., Kholodenko D., Malenka R.C., Nicoll R.A., and Mucke L. Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 3228-3233
17. Kamenetz F., Tomita T., Hsieh H., Seabrook G., Borchelt D., Iwatsubo T., Sisodia S., and Malinow R. APP processing and synaptic function. Neuron 37 (2003) 925-937
18. Kelly B.L., Vassar R., and Ferreira A. β-amyloid-induced dynamin 1 depletion in hippocampal neurons. A potential mechanism for early cognitive decline in Alzheimer disease. J. Biol. Chem. 280 (2005) 31746-31753
19. Lacor P.N., Buniel M.C., Chang L., Fernandez S.J., Gong Y., Viola K.L., Lambert M.P., Velasco P.T., Bigio E.H., Finch C.E., Krafft G.A., and Klein W.L. Synaptic targeting by Alzheimer's-related amyloid beta oligomers. J. Neurosci. 24 (2004) 10191-10200
20. Leslie K.R., Nelson S.B., and Turrigiano G.G. Postsynaptic depolarization scales quantal amplitude in cortical pyramidal neurons. J. Neurosci. 21 (2001) RC170
21. Masliah E., Mallory M., Hansen L., DeTeresa R., Alford M., and Terry R. Synaptic and neuritic alterations during the progression of Alzheimer's disease. Neurosci. Lett. 174 (1994) 67-72
22. Morris J.C., Storandt M., McKeel Jr. D.W., Rubin E.H., Price J.L., Grant E.A., and Berg L. Cerebral amyloid deposition and diffuse plaques in "normal" aging: evidence for presymptomatic and very mild Alzheimer's disease. Neurology 46 (1996) 707-719
23. Nägerl U.V., Mody I., Jeub M., Lie A.A., Elger C.E., and Beck H. Surviving granule cells of the sclerotic human hippocampus have reduced Ca(2+) influx because of a loss of calbindin-D(28 k) in temporal lobe epilepsy. J. Neurosci. 20 (2000) 1831-1836
24. Nishimura M., Owens J., and Swann J.W. Effects of chronic network hyperexcitability on the growth of hippocampal dendrites. Neurobiol. Dis. 29 (2008) 267-277
25. Oleskevich S., Alvarez F.J., and Walmsley B. Glycinergic miniature synaptic currents and receptor cluster sizes differ between spinal cord interneurons. J. Neurophysiol. 82 (1999) 312-319
26. Palop J.J., Jones B., Kekonius L., Chin J., Yu G.Q., Raber J., Masliah E., and Mucke L. Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 9572-9577
27. Palop J.J., Chin J., Roberson E.D., Wang J., Thwin M.T., Bien-Ly N., Yoo J., Ho K.O., Yu G.Q., Kreitzer A., Finkbeiner S., Noebels J.L., and Mucke L. Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. Neuron 55 (2007) 697-711
28. Puzzo D., Privitera L., Leznik E., Fà M., Staniszewski A., Palmeri A., and Arancio O. Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus. J. Neurosci. 28 (2008) 14537-14545
29. Selkoe D.J. Alzheimer's disease is a synaptic failure. Science 298 (2002) 789-791
30. Silva A.J., Kogan J.H., Frankland P.W., and Kida S. CREB and memory. Annu. Rev. Neurosci. 21 (1998) 127-148
31. Shankar G.M., Bloodgood B.L., Townsend M., Walsh D.M., Selkoe D.J., and Sabatini B.L. Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway. J. Neurosci. 27 (2007) 2866-2875
32. Snyder E.M., Nong Y., Almeida C.G., Paul S., Moran T., Choi E.Y., Nairn A.C., Salter M.W., Lombroso P.J., Gouras G.K., and Greengard P. Regulation of NMDA receptor trafficking by amyloid-beta. Nat. Neurosci. 8 (2005) 1051-1058
33. A receptors in developing spinal cord neurons: effects on neurite outgrowth. Neuroscience 108 (2001) 493-506
34. Turrigiano G.G. Homeostatic plasticity in neuronal networks: the more things change, the more they stay the same. Trends Neurosci. 22 (1999) 221-227
35. Turrigiano G.G., and Nelson S.B. Hebb and homeostatic in neuronal plasticity. Curr. Opin. Neurobiol. 10 (2000) 358-364
36. Turrigiano G.G., and Nelson S.B. Homeostatic plasticity in the developing nervous system. Nat. Rev. Neurosci. 5 (2004) 97-107
37. Walsh D.M., Klyubin I., Fadeeva J.V., Cullen W.K., Anwyl R., Wolfe M.S., Rowan M.J., and Selkoe D.J. Naturally secreted oligomers of Aβ protein potently inhibit hippocampal long-term potentiation in vivo. Nature 416 (2002) 535-539