Cortical synaptic integration in vivo is disrupted by amyloid-β plaques

Journal of Neuroscience

Volumn 24, Issue 19, 2004, Pages 4535-4540

  Stern, Edward A ^a   Bacskai, Brian J ^a   Hickey, Gregory A ^a   Attenello, Frank J ^a   Lombardo, Julianne A ^a   Hyman, Bradley T ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Alzheimer's disease; Amyloid plaques; In vivo; Neuronal geometry; Subthreshold membrane potential; Synaptic integration

Indexed keywords

AMYLOID BETA PROTEIN; PROTEIN PRECURSOR;

ACCURACY; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DYSFUNCTION; BRAIN NERVE CELL; COHORT ANALYSIS; CONTROLLED STUDY; CORPUS CALLOSUM; CORRELATION ANALYSIS; EAR; GEOMETRY; IN VIVO STUDY; INFORMATION PROCESSING; INNERVATION; MEMBRANE POTENTIAL; MOUSE; NEOCORTEX; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; RECORDING; SENILE PLAQUE; SYNAPSE; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ELECTRIC STIMULATION; ELECTRODES, IMPLANTED; ELECTROENCEPHALOGRAPHY; EVOKED POTENTIALS; MEMBRANE POTENTIALS; MICE; MICE, TRANSGENIC; NEURITES; PYRAMIDAL CELLS; SENILE PLAQUES; SYNAPTIC TRANSMISSION;

EID: 2442711566     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0462-04.2004     Document Type: Article

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