α4β2 nicotinic acetylcholine receptors are required for the amyloid β protein-induced suppression of long-term potentiation in rat hippocampal CA1 region in vivo

Brain Research Bulletin

Volumn 77, Issue 2-3, 2008, Pages 84-90

  Wu, M N ^a   He, Y X ^b   Guo, F ^a   Qi, J S ^a  

^a SHANXI MEDICAL UNIVERSITY   (China)

^b SHAANXI PROVINCIAL PEOPLE S HOSPITAL   (China)

Author keywords

Amyloid protein (A ); Hippocampus; In vivo; Long term potentiation (LTP); Nicotinic acetylcholine receptors (nAChRs)

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[25-35]; AMYLOID BETA PROTEIN[31-35]; EPIBATIDINE; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA4BETA2; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN (25 35); AMYLOID BETA PROTEIN (31 35); AMYLOID BETA-PROTEIN (25-35); AMYLOID BETA-PROTEIN (31-35); DIHYDRO BETA ERYTHROIDINE; FUSED HETEROCYCLIC RINGS; NICOTINIC AGENT; PEPTIDE FRAGMENT; PYRIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPUS; IN VIVO STUDY; LONG TERM POTENTIATION; MALE; NERVE CELL PLASTICITY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; DRUG EFFECT; GENETICS; HISTOLOGY; HUMAN; METABOLISM; PHYSIOLOGY; WISTAR RAT;

AMYLOID BETA-PROTEIN; ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; DIHYDRO-BETA-ERYTHROIDINE; ELECTROPHYSIOLOGY; EXCITATORY POSTSYNAPTIC POTENTIALS; HIPPOCAMPUS; HUMANS; LONG-TERM POTENTIATION; MALE; NEURONAL PLASTICITY; NICOTINIC AGONISTS; PEPTIDE FRAGMENTS; PYRIDINES; RATS; RATS, WISTAR; RECEPTORS, NICOTINIC;

EID: 51749094576     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2008.06.005     Document Type: Article

References (46)

1. Aggarwal N.T., Bienias J.L., Bennett D.A., Wilson R.S., Morris M.C., Schneider J.A., Shah R.C., and Evans D.A. The relation of cigarette smoking to incident Alzheimer's disease in a biracial urban community population. Neuroepidemiology 26 (2006) 140-146 (PubMed: 16493200)
2. Brenner D.E., Kukull W.A., van Belle G., Bowen J.D., McCormick W.C., Teri L., and Larson E.B. Relationship between cigarette smoking and Alzheimer's disease in a population-based case-control study. Neurology 43 (1993) 293-300 (PubMed: 8437692)
3. Chen L., Yamada K., Nabeshima T., and Sokabe M. Alpha7 nicotinic acetylcholine receptor as a target to rescue deficit in hippocampal LTP induction in beta-amyloid infused rats. Neuropharmacology 50 (2006) 254-268 (PubMed: 16324726)
4. Chen Q.S., Kagan B.L., Hirakura Y., and Xie C.W. Impairment of hippocampal long-term potentiation by Alzheimer amyloid beta-peptides. J. Neurosci. Res. 60 (2000) 65-72 (PubMed: 10723069)
5. Cheng H.Y. Evidence of acetylcholinesterase inhibitors in treating Alzheimer's disease in very old patients is uncertain. J. Am. Geriatr. Soc. 53 (2005) 1640 (PubMed: 16137311)
6. Chin J.H., Ma L., MacTavish D., and Jhamandas J.H. Amyloid beta protein modulates glutamate-mediated neurotransmission in the rat basal forebrain: involvement of presynaptic neuronal nicotinic acetylcholine and metabotropic glutamate receptors. J. Neurosci. 27 (2007) 9262-9269 (PubMed: 17728440)
7. Clementi M.E., Marini S., Coletta M., Orsini F., Giardina B., and Misiti F. Abeta (31-35) and Abeta (25-35) fragments of amyloid beta-protein induce cellular death through apoptotic signals: Role of the redox state of methionine-35. FEBS Lett 579 (2005) 2913-2918 (PubMed: 15890345)
8. Deng C., and Chen R. Effect of nicotine on induction of long-term potentiation in hippocampal CA 1 area of rat. Chin. Pharmacol. Bull. 15 (1999) 456-459 (PubMed:
9. Deshpande A., Mina E., Glabe C., and Busciglio J. Different conformations of amyloid beta induce neurotoxicity by distinct mechanisms in human cortical neurons. J. Neurosci. 26 (2006) 6011-6018 (PubMed: 16738244)
10. Egashira N., Iwasaki K., Akiyoshi Y., Takagaki Y., Hatip-Al-Khatib I., Mishima K., Kurauchi K., Ikeda T., and Fujiwara M. Protective effect of Toki-shakuyaku-san on amyloid beta 25-35-induced neuronal damage in cultured rat cortical neurons. Phytother. Res. 19 (2005) 450-453 (PubMed: 16106382)
11. Freir D.B., and Herron C.E. Nicotine enhances the depressive actions of A beta 1-40 on long-term potentiation in the rat hippocampal CA1 region in vivo. J. Neurophysiol. 89 (2003) 2917-2922 (PubMed: 12611941)
12. Freir D.B., Holscher C., and Herron C.E. Blockade of long-term potentiation by beta-amyloid peptides in the CA1 region of the rat hippocampus in vivo. J. Neurophysiol. 85 (2001) 708-713 (PubMed: 11160505)
13. Fu W., and Jhamandas J.H. Beta-amyloid peptide activates non-alpha7 nicotinic acetylcholine receptors in rat basal forebrain neurons. J. Neurophysiol. 90 (2003) 3130-3136 (PubMed: 12890800)
14. Graham A.J., Ray M.A., Perry E.K., Jaros E., Perry R.H., Volsen S.G., Bose S., Evans N., Lindstrom J., and Court J.A. Differential nicotinic acetylcholine receptor subunit expression in the human hippocampus. J. Chem. Neuroanat. 25 (2003) 97-113 (PubMed: 12663058)
15. Ji D., and Dani J.A. Inhibition and disinhibition of pyramidal neurons by activation of nicotinic receptors on hippocampal interneurons. J. Neurophysiol. 83 (2000) 2682-2690 (PubMed: 10805668)
16. Ji D., Lape R., and Dani J.A. Timing and location of nicotinic activity enhances or depresses hippocampal synaptic plasticity. Neuron 31 (2001) 131-141 (PubMed: 11498056)
17. Juan D., Zhou D.H., Li J., Wang J.Y., Gao C., and Chen M. A 2-year follow-up study of cigarette smoking and risk of dementia. Eur. J. Neurol. 11 (2004) 277-282 (PubMed: 15061830)
18. Kanski J., Varadarajan S., Aksenova M., and Butterfield D.A. Role of glycine-33 and methionine-35 in Alzheimer's amyloid beta-peptide 1-42-associated oxidative stress and neurotoxicity. Biochim. Biophys. Acta 1586 (2002) 190-198 (PubMed: 11959460)
19. Kawahara M. Disruption of calcium homeostasis in the pathogenesis of Alzheimer's disease and other conformational diseases. Curr. Alzheimer Res. 1 (2004) 87-95 (PubMed: 15975072)
20. Kawahara M., Arispe N., Kuroda Y., and Rojas E. Alzheimer's disease amyloid beta-protein forms Zn(2+)-sensitive, cation-selective channels across excised membrane patches from hypothalamic neurons. Biophys. J. 73 (1997) 67-75 (PubMed: 9199772)
21. Loo D.T., Copani A., Pike C.J., Whittemore E.R., Walencewicz A.J., and Cotman C.W. Apoptosis is induced by beta-amyloid in cultured central nervous system neurons. Proc. Natl. Acad. Sci. U.S.A. 90 (1993) 7951-7955 (PubMed: 8367446)
22. Matsuyama S., and Matsumoto A. Epibatidine induces long-term potentiation (LTP) via activation of alpha4beta2 nicotinic acetylcholine receptors (nAChRs) in vivo in the intact mouse dentate gyrus: both alpha7 and alpha4beta2 nAChRs essential to nicotinic LTP. J. Pharmacol. Sci. 93 (2003) 180-187 (PubMed: 14578586)
23. Misiti F., Sampaolese B., Pezzotti M., Marini S., Coletta M., Ceccarelli L., Giardina B., and Clementi M.E. Abeta (31-35) peptide induce apoptosis in PC 12 cells: contrast with Abeta (25-35) peptide and examination of underlying mechanisms. Neurochem. Int. 46 (2005) 575-583 (PubMed: 15843052)
24. Nakauchi S., Brennan R.J., Boulter J., and Sumikawa K. Nicotine gates long-term potentiation in the hippocampal CA1 region via the activation of alpha2* nicotinic ACh receptors. Eur. J. Neurosci. 25 (2007) 2666-2681 (PubMed: 17466021)
25. Oddo S., and LaFerla F.M. The role of nicotinic acetylcholine receptors in Alzheimer's disease. J. Physiol. Paris 99 (2006) 172-179 (PubMed: 16448808)
26. Pike C.J., Walencewicz-Wasserman A.J., Kosmoski J., Cribbs D.H., Glabe C.G., and Cotman C.W. Structure-activity analyses of beta-amyloid peptides: contributions of the beta 25-35 region to aggregation and neurotoxicity. J. Neurochem. 64 (1995) 253-265 (PubMed: 7798921)
27. Qi J.S., and Qiao J.T. Amyloid beta-protein fragment 31-35 forms ion channels in membrane patches excised from rat hippocampal neurons. Neuroscience 105 (2001) 845-852 (PubMed: 11530222)
28. + channels by amyloid beta-protein fragment 31-35 in membrane patches excised from hippocampal neurons. Acta Physiol. Sin. 53 (2001) 198-204 (PubMed: 12589404)
29. Roselli F., Tirard M., Lu J., Hutzler P., Lamberti P., Livrea P., Morabito M., and Almeida O.F. Soluble beta-amyloid 1-40 induces NMDA-dependent degradation of postsynaptic density-95 at glutamatergic synapses. J. Neurosci. 25 (2005) 11061-11070 (PubMed: 16319306)
30. Santos-Torres J., Fuente A., Criado J.M., Riolobos A.S., Heredia M., and Yajeya J. Glutamatergic synaptic depression by synthetic amyloid beta-peptide in the medial septum. J. Neurosci. Res. 85 (2007) 634-648 (PubMed: 17171714)
31. Selkoe D.J. The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease. Trends Cell Biol. 8 (1998) 447-453 (PubMed: 9854312)
32. Small D.H. Acetylcholinesterase inhibitors for the treatment of dementia in Alzheimer's disease: do we need new inhibitors?. Expert Opin. Emerg. Drugs 10 (2005) 817-825 (PubMed: 16262564)
33. Stepanichev M.Y., Moiseeva Y.V., Lazareva N.A., and Gulyaeva N.V. Studies of the effects of fragment (25-35) of beta-amyloid peptide on the behavior of rats in a radial maze. Neurosci. Behav. Physiol. 35 (2005) 511-518 (PubMed: 16033199)
34. Varadarajan S., Yatin S., Kanski J., Jahanshahi F., and Butterfield D.A. Methionine residue 35 is important in amyloid beta-peptide-associated free radical oxidative stress. Brain Res. Bull. 50 (1999) 133-141 (PubMed: 10535332)
35. Wallace W.C., Bragin V., Robakis N.K., Sambamurti K., VanderPutten D., Merril C.R., Davis K.L., Santucci A.C., and Haroutunian V. Increased biosynthesis of Alzheimer amyloid precursor protein in the cerebral cortex of rats with lesions of the nucleus basalis of Meynert. Brain Res. Mol. Brain Res. 10 (1991) 173-178 (PubMed: 1649369)
36. Wang H.Y., Lee D.H., Davis C.B., and Shank R.P. Amyloid peptide Abeta (1-42) binds selectively and with picomolar affinity to alpha7 nicotinic acetylcholine receptors. J. Neurochem. 75 (2000) 1155-1161 (PubMed: 10936198)
37. Wang Y., Sherwood J.L., and Lodge D. The alpha4beta2 nicotinic acetylcholine receptor agonist TC-2559 impairs long-term potentiation in the dentate gyrus in vivo. Neurosci. Lett. 406 (2006) 183-188 (PubMed: 16935422)
38. Welsby P.J., Rowan M.J., and Anwyl R. Beta-amyloid blocks high frequency stimulation induced LTP but not nicotine enhanced LTP. Neuropharmacology 53 (2007) 188-195 (PubMed: 17610911)
39. Whitehouse P.J., Price D.L., Struble R.G., Clark A.W., Coyle J.T., and Delon M.R. Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain. Science 215 (1982) 1237-1239 (PubMed: 7058341)
40. Yamazaki Y., Hamaue N., and Sumikawa K. Nicotine compensates for the loss of cholinergic function to enhance long-term potentiation induction. Brain Res. 946 (2002) 148-152 (PubMed: 12133604)
41. Yamazaki Y., Jia Y., Hamaue N., and Sumikawa K. Nicotine-induced switch in the nicotinic cholinergic mechanisms of facilitation of long-term potentiation induction. Eur. J. Neurosci. 22 (2005) 845-860 (PubMed: 16115208)
42. Yan X.Z., Qiao J.T., Dou Y., and Qiao Z.D. Beta-amyloid peptide fragment 31-35 induces apoptosis in cultured cortical neurons. Neuroscience 92 (1999) 177-184 (PubMed: 10392840)
43. Ye L., and Qiao J.T. Suppressive action produced by beta-amyloid peptide fragment 31-35 on long-term potentiation in rat hippocampus is N-methyl-d-aspartate receptor-independent: it's offset by (-)huperzine A. Neurosci. Lett. 275 (1999) 187-190 (PubMed: 10580706)
44. Zamani M.R., and Allen Y.S. Nicotine and its interaction with beta-amyloid protein: a short review. Biol. Psychiatry 49 (2001) 221-232 (PubMed: 11230873)
45. Zhang J.M., Wu M.N., Qi J.S., and Qiao J.T. Amyloid beta-protein fragment 31-35 suppresses long-term potentiation in hippocampal CA1 region of rats in vivo. Synapse 60 (2006) 307-313 (PubMed: 16786537)
46. Zhang L., Rubinow D.R., Xaing G., Li B.S., Chang Y.H., Maric D., Barker J.L., and Ma W. Estrogen protects against beta-amyloid-induced neurotoxicity in rat hippocampal neurons by activation of Akt. Neuroreport 12 (2001) 1919-1923 (PubMed: 11435923)