Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses

Neurobiology of Disease

Volumn 20, Issue 2, 2005, Pages 187-198

  Almeida, Claudia G ^a   Tampellini, Davide ^a   Takahashi, Reisuke H ^a   Greengard, Paul ^b   Lin, Michael T ^a   Snyder, Eric M ^b   Gouras, Gunnar K ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Alzheimer; AMPA; Amyloid; Dendrite; Glutamate receptor; Spines; Synapse

Indexed keywords

AMYLOID BETA PROTEIN; GAMMA SECRETASE; GLUTAMATE RECEPTOR; POSTSYNAPTIC DENSITY PROTEIN 95;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; ENZYME INHIBITION; GENE MUTATION; MOUSE; NERVE CELL; NONHUMAN; POSTSYNAPTIC MEMBRANE; PRIORITY JOURNAL; SYNAPSE; TRANSGENIC MOUSE; WILD TYPE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; BRAIN; CELLS, CULTURED; DENDRITIC SPINES; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ENDOPEPTIDASES; ENZYME INHIBITORS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; MUTATION; RECEPTORS, AMPA; SYNAPSES; SYNAPTIC MEMBRANES; SYNAPTIC TRANSMISSION;

EID: 26944467176     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2005.02.008     Document Type: Article

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