-
1
-
-
0027508926
-
Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: Blockade by tromethamine and aluminum
-
Arispe, N., Rojas, E., and Pollard, H. B. (1993). Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum. Proc Natl Acad Sci U S A 90, 567-571.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 567-571
-
-
Arispe, N.1
Rojas, E.2
Pollard, H.B.3
-
2
-
-
0034529080
-
A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's beta-secretase
-
Bennett, B. D., Denis, P., Haniu, M., Teplow, D. B., Kahn, S., Louis, J. C., Citron, M., and Vassar, R. (2000). A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's beta-secretase. J Biol Chem 275, 37712-37717.
-
(2000)
J Biol Chem
, vol.275
, pp. 37712-37717
-
-
Bennett, B.D.1
Denis, P.2
Haniu, M.3
Teplow, D.B.4
Kahn, S.5
Louis, J.C.6
Citron, M.7
Vassar, R.8
-
3
-
-
0033370498
-
Evidence for glial-mediated inflammation in aged APP(SW) transgenic mice
-
Benzing, W. C., Wujek, J. R., Ward, E. K., Shaffer, D., Ashe, K. H., Younkin, S. G., and Brunden, K. R. (1999). Evidence for glial-mediated inflammation in aged APP(SW) transgenic mice. Neurobiol Aging 20, 581-589.
-
(1999)
Neurobiol Aging
, vol.20
, pp. 581-589
-
-
Benzing, W.C.1
Wujek, J.R.2
Ward, E.K.3
Shaffer, D.4
Ashe, K.H.5
Younkin, S.G.6
Brunden, K.R.7
-
4
-
-
14644442872
-
Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice
-
Billings, L. M., Oddo, S., Green, K. N., McGaugh, J. L., and LaFerla, F. M. (2005). Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice. Neuron 45, 675-688.
-
(2005)
Neuron
, vol.45
, pp. 675-688
-
-
Billings, L.M.1
Oddo, S.2
Green, K.N.3
McGaugh, J.L.4
LaFerla, F.M.5
-
5
-
-
0027476024
-
A synaptic model of memory: Long-term potentiation in the hippocampus
-
Bliss, T. V., and Collingridge, G. L. (1993). A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361, 31-39.
-
(1993)
Nature
, vol.361
, pp. 31-39
-
-
Bliss, T.V.1
Collingridge, G.L.2
-
6
-
-
3042578511
-
Incubation of nerve endings with a physiological concentration of Abeta1-42 activates CaV2.2(N-Type)-voltage operated calcium channels and acutely increases glutamate and noradrenaline release
-
Bobich, J. A., Zheng, Q., and Campbell, A. (2004). Incubation of nerve endings with a physiological concentration of Abeta1-42 activates CaV2.2(N-Type)-voltage operated calcium channels and acutely increases glutamate and noradrenaline release. J Alzheimers Dis 6, 243-255.
-
(2004)
J Alzheimers Dis
, vol.6
, pp. 243-255
-
-
Bobich, J.A.1
Zheng, Q.2
Campbell, A.3
-
8
-
-
33344458827
-
M1 receptors play a central role in modulating AD-like pathology in transgenic mice
-
Caccamo, A., Oddo, S., Billings, L. M., Green, K. N., Martinez-Coria, H., Fisher, A., and LaFerla, F. M. (2006). M1 receptors play a central role in modulating AD-like pathology in transgenic mice. Neuron 49, 671-682.
-
(2006)
Neuron
, vol.49
, pp. 671-682
-
-
Caccamo, A.1
Oddo, S.2
Billings, L.M.3
Green, K.N.4
Martinez-Coria, H.5
Fisher, A.6
LaFerla, F.M.7
-
9
-
-
0033360356
-
Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice
-
Chapman, P. F., White, G. L., Jones, M. W., Cooper-Blacketer, D., Marshall, V. J., Irizarry, M., Younkin, L., Good, M. A., Bliss, T. V., Hyman, B. T., et al. (1999). Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice. Nat Neurosci 2, 271-276.
-
(1999)
Nat Neurosci
, vol.2
, pp. 271-276
-
-
Chapman, P.F.1
White, G.L.2
Jones, M.W.3
Cooper-Blacketer, D.4
Marshall, V.J.5
Irizarry, M.6
Younkin, L.7
Good, M.A.8
Bliss, T.V.9
Hyman, B.T.10
-
10
-
-
1542512477
-
Stimulation of beta-amyloid precursor protein alpha-processing by phorbol ester involves calcium and calpain activation
-
Chen, M., and Fernandez, H. L. (2004). Stimulation of beta-amyloid precursor protein alpha-processing by phorbol ester involves calcium and calpain activation. Biochem Biophys Res Commun 316, 332-340.
-
(2004)
Biochem Biophys Res Commun
, vol.316
, pp. 332-340
-
-
Chen, M.1
Fernandez, H.L.2
-
11
-
-
0034069795
-
Impairment of hippocampal long-term potentiation by Alzheimer amyloid beta-peptides
-
Chen, Q. S., Kagan, B. L., Hirakura, Y., and Xie, C. W. (2000). Impairment of hippocampal long-term potentiation by Alzheimer amyloid beta-peptides. J Neurosci Res 60, 65-72.
-
(2000)
J Neurosci Res
, vol.60
, pp. 65-72
-
-
Chen, Q.S.1
Kagan, B.L.2
Hirakura, Y.3
Xie, C.W.4
-
12
-
-
29144487182
-
Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo
-
Cirrito, J. R., Yamada, K. A., Finn, M. B., Sloviter, R. S., Bales, K. R., May, P. C., Schoepp, D. D., Paul, S. M., Mennerick, S., and Holtzman, D. M. (2005). Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo. Neuron 48, 913-922.
-
(2005)
Neuron
, vol.48
, pp. 913-922
-
-
Cirrito, J.R.1
Yamada, K.A.2
Finn, M.B.3
Sloviter, R.S.4
Bales, K.R.5
May, P.C.6
Schoepp, D.D.7
Paul, S.M.8
Mennerick, S.9
Holtzman, D.M.10
-
14
-
-
0033393340
-
L-type calcium channels in the hippocampus and cerebellum of Alzheimer's disease brain tissue
-
Coon, A. L., Wallace, D. R., Mactutus, C. F., and Booze, R. M. (1999). L-type calcium channels in the hippocampus and cerebellum of Alzheimer's disease brain tissue. Neurobiol Aging 20, 597-603.
-
(1999)
Neurobiol Aging
, vol.20
, pp. 597-603
-
-
Coon, A.L.1
Wallace, D.R.2
Mactutus, C.F.3
Booze, R.M.4
-
15
-
-
0345405447
-
Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles
-
Cruz, J. C., Tseng, H. C., Goldman, J. A., Shih, H., and Tsai, L. H. (2003). Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles. Neuron 40, 471-483.
-
(2003)
Neuron
, vol.40
, pp. 471-483
-
-
Cruz, J.C.1
Tseng, H.C.2
Goldman, J.A.3
Shih, H.4
Tsai, L.H.5
-
16
-
-
0030513943
-
Structural correlates of cognition in dementia: Quantification and assessment of synapse change
-
DeKosky, S. T., Scheff, S. W., and Styren, S. D. (1996). Structural correlates of cognition in dementia: quantification and assessment of synapse change. Neurodegeneration 5, 417-421.
-
(1996)
Neurodegeneration
, vol.5
, pp. 417-421
-
-
DeKosky, S.T.1
Scheff, S.W.2
Styren, S.D.3
-
17
-
-
20444496481
-
Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers
-
Demuro, A., Mina, E., Kayed, R., Milton, S. C., Parker, I., and Glabe, C. G. (2005). Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers. J Biol Chem 280, 17294-17300.
-
(2005)
J Biol Chem
, vol.280
, pp. 17294-17300
-
-
Demuro, A.1
Mina, E.2
Kayed, R.3
Milton, S.C.4
Parker, I.5
Glabe, C.G.6
-
18
-
-
0033569760
-
Activation of the L voltage-sensitive calcium channel by mitogen-activated protein (MAP) kinase following exposure of neuronal cells to beta-amyloid. MAP kinase mediates beta-amyloid-induced neurodegeneration
-
Ekinci, F. J., Malik, K. U., and Shea, T. B. (1999). Activation of the L voltage-sensitive calcium channel by mitogen-activated protein (MAP) kinase following exposure of neuronal cells to beta-amyloid. MAP kinase mediates beta-amyloid-induced neurodegeneration. J Biol Chem 274, 30322-30327.
-
(1999)
J Biol Chem
, vol.274
, pp. 30322-30327
-
-
Ekinci, F.J.1
Malik, K.U.2
Shea, T.B.3
-
19
-
-
33750156019
-
Alpha-secretase activation-an approach to Alzheimer's disease therapy
-
Fahrenholz, F., and Postina, R. (2006). Alpha-secretase activation-an approach to Alzheimer's disease therapy. Neurodegener Dis 3, 255-261.
-
(2006)
Neurodegener Dis
, vol.3
, pp. 255-261
-
-
Fahrenholz, F.1
Postina, R.2
-
20
-
-
0028978364
-
Diminished [3H]inositol(1,4,5)P3 but not [3H]inositol(1,3,4,5)P4 binding in Alzheimer's disease brain
-
Garlind, A., Cowburn, R. F., Forsell, C., Ravid, R., Winblad, B., and Fowler, C. J. (1995). Diminished [3H]inositol(1,4,5)P3 but not [3H]inositol(1,3,4,5)P4 binding in Alzheimer's disease brain. Brain Res 681, 160-166.
-
(1995)
Brain Res
, vol.681
, pp. 160-166
-
-
Garlind, A.1
Cowburn, R.F.2
Forsell, C.3
Ravid, R.4
Winblad, B.5
Fowler, C.J.6
-
21
-
-
0023198092
-
Diminished mitogen-induced calcium uptake by lymphocytes from Alzheimer patients
-
Gibson, G. E., Nielsen, P., Sherman, K. A., and Blass, J. P. (1987). Diminished mitogen-induced calcium uptake by lymphocytes from Alzheimer patients. Biol Psychiatry 22, 1079-1086.
-
(1987)
Biol Psychiatry
, vol.22
, pp. 1079-1086
-
-
Gibson, G.E.1
Nielsen, P.2
Sherman, K.A.3
Blass, J.P.4
-
22
-
-
33750379305
-
Amyloid beta-peptide preconditioning reduces glutamate-induced neurotoxicity by promoting endocytosis of NMDA receptor
-
Goto, Y., Niidome, T., Akaike, A., Kihara, T., and Sugimoto, H. (2006). Amyloid beta-peptide preconditioning reduces glutamate-induced neurotoxicity by promoting endocytosis of NMDA receptor. Biochem Biophys Res Commun 351, 259-265.
-
(2006)
Biochem Biophys Res Commun
, vol.351
, pp. 259-265
-
-
Goto, Y.1
Niidome, T.2
Akaike, A.3
Kihara, T.4
Sugimoto, H.5
-
23
-
-
0035020810
-
Amyloid beta peptides mediate hypoxic augmentation of Ca(2+) channels
-
Green, K. N., and Peers, C. (2001). Amyloid beta peptides mediate hypoxic augmentation of Ca(2+) channels. J Neurochem 77, 953-956.
-
(2001)
J Neurochem
, vol.77
, pp. 953-956
-
-
Green, K.N.1
Peers, C.2
-
24
-
-
0036312008
-
Divergent pathways account for two distinct effects of amyloid beta peptides on exocytosis and Ca(2+) currents: Involvement of ROS and NF-kappaB
-
Green, K. N., and Peers, C. (2002). Divergent pathways account for two distinct effects of amyloid beta peptides on exocytosis and Ca(2+) currents: involvement of ROS and NF-kappaB. J Neurochem 81, 1043-1051.
-
(2002)
J Neurochem
, vol.81
, pp. 1043-1051
-
-
Green, K.N.1
Peers, C.2
-
25
-
-
0023100229
-
Dementia of the Alzheimer's type: Changes in hippocampal L-[3H]glutamate binding
-
Greenamyre, J. T., Penney, J. B., D'Amato, C. J., and Young, A. B. (1987). Dementia of the Alzheimer's type: changes in hippocampal L-[3H]glutamate binding. J Neurochem 48, 543-551.
-
(1987)
J Neurochem
, vol.48
, pp. 543-551
-
-
Greenamyre, J.T.1
Penney, J.B.2
D'Amato, C.J.3
Young, A.B.4
-
26
-
-
0030836467
-
Active site-directed antibodies identify calpain II as an early-appearing and pervasive component of neurofibrillary pathology in Alzheimer's disease
-
Grynspan, F., Griffin, W. R., Cataldo, A., Katayama, S., and Nixon, R. A. (1997). Active site-directed antibodies identify calpain II as an early-appearing and pervasive component of neurofibrillary pathology in Alzheimer's disease. Brain Res 763, 145-158.
-
(1997)
Brain Res
, vol.763
, pp. 145-158
-
-
Grynspan, F.1
Griffin, W.R.2
Cataldo, A.3
Katayama, S.4
Nixon, R.A.5
-
27
-
-
0035255082
-
Human platelet calcium mobilisation in response to beta-amyloid (25-35): Buffer dependency and unchanged response in Alzheimer's disease
-
Hedin, H. L., Eriksson, S., and Fowler, C. J. (2001). Human platelet calcium mobilisation in response to beta-amyloid (25-35): buffer dependency and unchanged response in Alzheimer's disease. Neurochem Int 38, 1450-151.
-
(2001)
Neurochem Int
, vol.38
, pp. 1450-1451
-
-
Hedin, H.L.1
Eriksson, S.2
Fowler, C.J.3
-
28
-
-
0029787370
-
Calcium responses in human fibroblasts: A diagnostic molecular profile for Alzheimer's disease
-
Hirashima, N., Etcheberrigaray, R., Bergamaschi, S., Racchi, M., Battaini, F., Binetti, G., Govoni, S., and Alkon, D. L. (1996). Calcium responses in human fibroblasts: a diagnostic molecular profile for Alzheimer's disease. Neurobiol Aging 17, 549-555.
-
(1996)
Neurobiol Aging
, vol.17
, pp. 549-555
-
-
Hirashima, N.1
Etcheberrigaray, R.2
Bergamaschi, S.3
Racchi, M.4
Battaini, F.5
Binetti, G.6
Govoni, S.7
Alkon, D.L.8
-
29
-
-
0031914718
-
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
-
Holcomb, L., Gordon, M. N., McGowan, E., Yu, X., Benkovic, S., Jantzen, P., Wright, K., Saad, I., Mueller, R., Morgan, D., et al. (1998). Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes. Nat Med 4, 97-100.
-
(1998)
Nat Med
, vol.4
, pp. 97-100
-
-
Holcomb, L.1
Gordon, M.N.2
McGowan, E.3
Yu, X.4
Benkovic, S.5
Jantzen, P.6
Wright, K.7
Saad, I.8
Mueller, R.9
Morgan, D.10
-
30
-
-
0025946570
-
Inositol phosphates and intracellular calcium after bradykinin stimulation in fibroblasts from young, normal aged and Alzheimer donors
-
Huang, H. M., Toral-Barza, L., Thaler, H., Tofel-Grehl, B., and Gibson, G. E. (1991). Inositol phosphates and intracellular calcium after bradykinin stimulation in fibroblasts from young, normal aged and Alzheimer donors. Neurobiol Aging 12, 469-473.
-
(1991)
Neurobiol Aging
, vol.12
, pp. 469-473
-
-
Huang, H.M.1
Toral-Barza, L.2
Thaler, H.3
Tofel-Grehl, B.4
Gibson, G.E.5
-
32
-
-
0031226399
-
Molecular mechanism of neuronal death in Alzheimer's disease: Ca(2+)-channel formation of beta amyloid protein molecules
-
Kawahara, M., and Kuroda, Y. (1997). [Molecular mechanism of neuronal death in Alzheimer's disease: Ca(2+)-channel formation of beta amyloid protein molecules]. Tanpakushitsu Kakusan Koso 42, 2002-2010.
-
(1997)
Tanpakushitsu Kakusan Koso
, vol.42
, pp. 2002-2010
-
-
Kawahara, M.1
Kuroda, Y.2
-
33
-
-
0024515583
-
Limited proteolysis of protein kinase C subspecies by calcium-dependent neutral protease (calpain)
-
Kishimoto, A., Mikawa, K., Hashimoto, K., Yasuda, I., Tanaka, S., Tominaga, M., Kuroda, T., and Nishizuka, Y. (1989). Limited proteolysis of protein kinase C subspecies by calcium-dependent neutral protease (calpain). J Biol Chem 264, 4088-4092.
-
(1989)
J Biol Chem
, vol.264
, pp. 4088-4092
-
-
Kishimoto, A.1
Mikawa, K.2
Hashimoto, K.3
Yasuda, I.4
Tanaka, S.5
Tominaga, M.6
Kuroda, T.7
Nishizuka, Y.8
-
34
-
-
0036830947
-
Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease
-
LaFerla, F. M. (2002). Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease. Nat Rev Neurosci 3, 862-872.
-
(2002)
Nat Rev Neurosci
, vol.3
, pp. 862-872
-
-
LaFerla, F.M.1
-
35
-
-
0035093856
-
Cdk5 at the junction
-
Lee, M. S., and Tsai, L. H. (2001). Cdk5 at the junction. Nat Neurosci 4, 340-342.
-
(2001)
Nat Neurosci
, vol.4
, pp. 340-342
-
-
Lee, M.S.1
Tsai, L.H.2
-
36
-
-
0034657414
-
Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice
-
Leissring, M. A., Akbari, Y., Fanger, C. M., Cahalan, M. D., Mattson, M. P., and LaFerla, F. M. (2000). Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice. J Cell Biol 149, 793-798.
-
(2000)
J Cell Biol
, vol.149
, pp. 793-798
-
-
Leissring, M.A.1
Akbari, Y.2
Fanger, C.M.3
Cahalan, M.D.4
Mattson, M.P.5
LaFerla, F.M.6
-
37
-
-
0035503597
-
The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse
-
Lim, G. P., Chu, T., Yang, F., Beech, W., Frautschy, S. A., and Cole, G. M. (2001). The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J Neurosci 21, 8370-8377.
-
(2001)
J Neurosci
, vol.21
, pp. 8370-8377
-
-
Lim, G.P.1
Chu, T.2
Yang, F.3
Beech, W.4
Frautschy, S.A.5
Cole, G.M.6
-
38
-
-
27844553889
-
Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain
-
Liu, F., Grundke-Iqbal, I., Iqbal, K., Oda, Y., Tomizawa, K., and Gong, C. X. (2005). Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain. J Biol Chem 280, 37755-37762.
-
(2005)
J Biol Chem
, vol.280
, pp. 37755-37762
-
-
Liu, F.1
Grundke-Iqbal, I.2
Iqbal, K.3
Oda, Y.4
Tomizawa, K.5
Gong, C.X.6
-
39
-
-
0035836747
-
beta -Amyloid peptide blocks the response of alpha 7-containing nicotinic receptors on hippocampal neurons
-
Liu, Q., Kawai, H., and Berg, D. K. (2001). beta -Amyloid peptide blocks the response of alpha 7-containing nicotinic receptors on hippocampal neurons. Proc Natl Acad Sci U S A 98, 4734-4739.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 4734-4739
-
-
Liu, Q.1
Kawai, H.2
Berg, D.K.3
-
40
-
-
0032573097
-
Amyloid beta peptide alters intracellular vesicle trafficking and cholesterol homeostasis
-
Liu, Y., Peterson, D. A., and Schubert, D. (1998). Amyloid beta peptide alters intracellular vesicle trafficking and cholesterol homeostasis. Proc Natl Acad Sci U S A 95, 13266-13271.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 13266-13271
-
-
Liu, Y.1
Peterson, D.A.2
Schubert, D.3
-
41
-
-
0030695856
-
Cytotoxic amyloid peptides inhibit cellular 3-(4,5-dimethylthiazol- 2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction by enhancing MTT formazan exocytosis
-
Liu, Y., and Schubert, D. (1997). Cytotoxic amyloid peptides inhibit cellular 3-(4,5-dimethylthiazol- 2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction by enhancing MTT formazan exocytosis. J Neurochem 69, 2285-2293.
-
(1997)
J Neurochem
, vol.69
, pp. 2285-2293
-
-
Liu, Y.1
Schubert, D.2
-
42
-
-
0022650213
-
Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5
-
Morris, R. G., Anderson, E., Lynch, G. S., and Baudry, M. (1986). Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5. Nature 319, 774-776.
-
(1986)
Nature
, vol.319
, pp. 774-776
-
-
Morris, R.G.1
Anderson, E.2
Lynch, G.S.3
Baudry, M.4
-
43
-
-
0028544333
-
Memory impairment and neuronal dysfunction induced by beta-amyloid protein in rats
-
Nabeshima, T., and Nitta, A. (1994). Memory impairment and neuronal dysfunction induced by beta-amyloid protein in rats. Tohoku J Exp Med 174, 241-249.
-
(1994)
Tohoku J Exp Med
, vol.174
, pp. 241-249
-
-
Nabeshima, T.1
Nitta, A.2
-
44
-
-
27844510969
-
Mechanism of impairment of long-term potentiation by amyloid beta is independent of NMDA receptors or voltage-dependent calcium channels in hippocampal CA1 pyramidal neurons
-
Nomura, I., Kato, N., Kita, T., and Takechi, H. (2005). Mechanism of impairment of long-term potentiation by amyloid beta is independent of NMDA receptors or voltage-dependent calcium channels in hippocampal CA1 pyramidal neurons. Neurosci Lett 391, 1-6.
-
(2005)
Neurosci Lett
, vol.391
, pp. 1-6
-
-
Nomura, I.1
Kato, N.2
Kita, T.3
Takechi, H.4
-
45
-
-
4043167747
-
Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome
-
Oddo, S., Billings, L., Kesslak, J. P., Cribbs, D. H., and LaFerla, F. M. (2004). Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome. Neuron 43, 321-332.
-
(2004)
Neuron
, vol.43
, pp. 321-332
-
-
Oddo, S.1
Billings, L.2
Kesslak, J.P.3
Cribbs, D.H.4
LaFerla, F.M.5
-
46
-
-
0344845132
-
Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease
-
Oddo, S., Caccamo, A., Kitazawa, M., Tseng, B. P., and LaFerla, F. M. (2003a). Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease. Neurobiol Aging 24, 1063-1070.
-
(2003)
Neurobiol Aging
, vol.24
, pp. 1063-1070
-
-
Oddo, S.1
Caccamo, A.2
Kitazawa, M.3
Tseng, B.P.4
LaFerla, F.M.5
-
47
-
-
0042697305
-
Triple-transgenic model of Alzheimer's disease with plaques and tangles: Intracellular Abeta and synaptic dysfunction
-
Oddo, S., Caccamo, A., Shepherd, J. D., Murphy, M. P., Golde, T. E., Kayed, R., Metherate, R., Mattson, M. P., Akbari, Y., and LaFerla, F. M. (2003b). Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron 39, 409-421.
-
(2003)
Neuron
, vol.39
, pp. 409-421
-
-
Oddo, S.1
Caccamo, A.2
Shepherd, J.D.3
Murphy, M.P.4
Golde, T.E.5
Kayed, R.6
Metherate, R.7
Mattson, M.P.8
Akbari, Y.9
LaFerla, F.M.10
-
48
-
-
33144487701
-
Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology
-
Oddo, S., Caccamo, A., Tran, L., Lambert, M. P., Glabe, C. G., Klein, W. L., and LaFerla, F. M. (2006). Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology. J Biol Chem 281, 1599-1604.
-
(2006)
J Biol Chem
, vol.281
, pp. 1599-1604
-
-
Oddo, S.1
Caccamo, A.2
Tran, L.3
Lambert, M.P.4
Glabe, C.G.5
Klein, W.L.6
LaFerla, F.M.7
-
50
-
-
33746924907
-
Memantine treatment in mild to moderate Alzheimer disease: A 24-week randomized, controlled trial
-
Peskind, E. R., Potkin, S. G., Pomara, N., Ott, B. R., Graham, S. M., Olin, J. T., and McDonald, S. (2006). Memantine treatment in mild to moderate Alzheimer disease: a 24-week randomized, controlled trial. Am J Geriatr Psychiatry 14, 704-715.
-
(2006)
Am J Geriatr Psychiatry
, vol.14
, pp. 704-715
-
-
Peskind, E.R.1
Potkin, S.G.2
Pomara, N.3
Ott, B.R.4
Graham, S.M.5
Olin, J.T.6
McDonald, S.7
-
51
-
-
0022001659
-
Altered calcium uptake in cultured skin fibroblasts from patients with Alzheimer's disease
-
Peterson, C., Gibson, G. E., and Blass, J. P. (1985). Altered calcium uptake in cultured skin fibroblasts from patients with Alzheimer's disease. N Engl J Med 312, 1063-1065.
-
(1985)
N Engl J Med
, vol.312
, pp. 1063-1065
-
-
Peterson, C.1
Gibson, G.E.2
Blass, J.P.3
-
52
-
-
0343050763
-
Alterations in calcium content and biochemical processes in cultured skin fibroblasts from aged and Alzheimer donors
-
Peterson, C., and Goldman, J. E. (1986). Alterations in calcium content and biochemical processes in cultured skin fibroblasts from aged and Alzheimer donors. Proc Natl Acad Sci U S A 83, 2758-2762.
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 2758-2762
-
-
Peterson, C.1
Goldman, J.E.2
-
53
-
-
0023037796
-
Cytosolic free calcium and cell spreading decrease in fibroblasts from aged and Alzheimer donors
-
Peterson, C., Ratan, R. R., Shelanski, M. L., and Goldman, J. E. (1986). Cytosolic free calcium and cell spreading decrease in fibroblasts from aged and Alzheimer donors. Proc Natl Acad Sci U S A 83, 7999-8001.
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 7999-8001
-
-
Peterson, C.1
Ratan, R.R.2
Shelanski, M.L.3
Goldman, J.E.4
-
54
-
-
0024156569
-
Altered response of fibroblasts from aged and Alzheimer donors to drugs that elevate cytosolic free calcium
-
Peterson, C., Ratan, R. R., Shelanski, M. L., and Goldman, J. E. (1988). Altered response of fibroblasts from aged and Alzheimer donors to drugs that elevate cytosolic free calcium. Neurobiol Aging 9, 261-266.
-
(1988)
Neurobiol Aging
, vol.9
, pp. 261-266
-
-
Peterson, C.1
Ratan, R.R.2
Shelanski, M.L.3
Goldman, J.E.4
-
55
-
-
0030472049
-
Elevated intracellular calcium concentration increases secretory processing of the amyloid precursor protein by a tyrosine phosphorylationdependent mechanism
-
Petryniak, M. A., Wurtman, R. J., and Slack, B. E. (1996). Elevated intracellular calcium concentration increases secretory processing of the amyloid precursor protein by a tyrosine phosphorylationdependent mechanism. Biochem J 320 (Pt 3), 957-963.
-
(1996)
Biochem J
, vol.320
, pp. 957-963
-
-
Petryniak, M.A.1
Wurtman, R.J.2
Slack, B.E.3
-
56
-
-
0035219699
-
beta-Amyloid(1-42) peptide directly modulates nicotinic receptors in the rat hippocampal slice
-
Pettit, D. L., Shao, Z., and Yakel, J. L. (2001). beta-Amyloid(1-42) peptide directly modulates nicotinic receptors in the rat hippocampal slice. J Neurosci 21, RC120.
-
(2001)
J Neurosci
, vol.21
-
-
Pettit, D.L.1
Shao, Z.2
Yakel, J.L.3
-
57
-
-
1442323991
-
Intraneuronal amyloid-beta1-42 production triggered by sustained increase of cytosolic calcium concentration induces neuronal death
-
Pierrot, N., Ghisdal, P., Caumont, A. S., and Octave, J. N. (2004). Intraneuronal amyloid-beta1-42 production triggered by sustained increase of cytosolic calcium concentration induces neuronal death. J Neurochem 88, 1140-1150.
-
(2004)
J Neurochem
, vol.88
, pp. 1140-1150
-
-
Pierrot, N.1
Ghisdal, P.2
Caumont, A.S.3
Octave, J.N.4
-
58
-
-
0023101383
-
Phosphorylation by protein kinase C of a 20-kDa cytoskeletal polypeptide enhances its susceptibility to digestion by calpain
-
Pontremoli, S., Melloni, E., Michetti, M., Sparatore, B., Salamino, F., Sacco, O., and Horecker, B. L. (1987). Phosphorylation by protein kinase C of a 20-kDa cytoskeletal polypeptide enhances its susceptibility to digestion by calpain. Proc Natl Acad Sci U S A 84, 398-401.
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 398-401
-
-
Pontremoli, S.1
Melloni, E.2
Michetti, M.3
Sparatore, B.4
Salamino, F.5
Sacco, O.6
Horecker, B.L.7
-
60
-
-
0030987603
-
Caffeine stimulates amyloid betapeptide release from beta-amyloid precursor protein-transfected HEK293 cells
-
Querfurth, H. W., Jiang, J., Geiger, J. D., and Selkoe, D. J. (1997). Caffeine stimulates amyloid betapeptide release from beta-amyloid precursor protein-transfected HEK293 cells. J Neurochem 69, 1580-1591.
-
(1997)
J Neurochem
, vol.69
, pp. 1580-1591
-
-
Querfurth, H.W.1
Jiang, J.2
Geiger, J.D.3
Selkoe, D.J.4
-
61
-
-
0028204224
-
Calcium ionophore increases amyloid beta peptide production by cultured cells
-
Querfurth, H. W., and Selkoe, D. J. (1994). Calcium ionophore increases amyloid beta peptide production by cultured cells. Biochemistry 33, 4550-4561.
-
(1994)
Biochemistry
, vol.33
, pp. 4550-4561
-
-
Querfurth, H.W.1
Selkoe, D.J.2
-
62
-
-
0034763569
-
Differential effects of unaggregated and aggregated amyloid beta protein (1-40) on K(+) channel currents in primary cultures of rat cerebellar granule and cortical neurones
-
Ramsden, M., Plant, L. D., Webster, N. J., Vaughan, P. F., Henderson, Z., and Pearson, H. A. (2001). Differential effects of unaggregated and aggregated amyloid beta protein (1-40) on K(+) channel currents in primary cultures of rat cerebellar granule and cortical neurones. J Neurochem 79, 699-712.
-
(2001)
J Neurochem
, vol.79
, pp. 699-712
-
-
Ramsden, M.1
Plant, L.D.2
Webster, N.J.3
Vaughan, P.F.4
Henderson, Z.5
Pearson, H.A.6
-
63
-
-
4143132081
-
Alterations in calcium homeostasis as biological marker for mild Alzheimer's disease?
-
Ripova, D., Platilova, V., Strunecka, A., Jirak, R., and Hoschl, C. (2004). Alterations in calcium homeostasis as biological marker for mild Alzheimer's disease? Physiol Res 53, 449-452.
-
(2004)
Physiol Res
, vol.53
, pp. 449-452
-
-
Ripova, D.1
Platilova, V.2
Strunecka, A.3
Jirak, R.4
Hoschl, C.5
-
64
-
-
0034282066
-
Cytosolic calcium alterations in platelets of patients with early stages of Alzheimer's disease
-
Ripovi, D., Platilova, V., Strunecka, A., Jirak, R., and Hoschl, C. (2000). Cytosolic calcium alterations in platelets of patients with early stages of Alzheimer's disease. Neurobiol Aging 21, 729-734.
-
(2000)
Neurobiol Aging
, vol.21
, pp. 729-734
-
-
Ripovi, D.1
Platilova, V.2
Strunecka, A.3
Jirak, R.4
Hoschl, C.5
-
65
-
-
0027474051
-
Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: A potential molecular basis for neuronal degeneration
-
Saito, K., Elce, J. S., Hamos, J. E., and Nixon, R. A. (1993). Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration. Proc Natl Acad Sci U S A 90, 2628-2632.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 2628-2632
-
-
Saito, K.1
Elce, J.S.2
Hamos, J.E.3
Nixon, R.A.4
-
67
-
-
0033638106
-
Activity-dependent induction of tonic calcineurin activity mediates a rapid developmental downregulation of NMDA receptor currents
-
Shi, J., Townsend, M., and Constantine-Paton, M. (2000). Activity-dependent induction of tonic calcineurin activity mediates a rapid developmental downregulation of NMDA receptor currents. Neuron 28, 103-114.
-
(2000)
Neuron
, vol.28
, pp. 103-114
-
-
Shi, J.1
Townsend, M.2
Constantine-Paton, M.3
-
68
-
-
0035971166
-
The pro domain of beta-secretase does not confer strict zymogen-like properties but does assist proper folding of the protease domain
-
Shi, X. P., Chen, E., Yin, K. C., Na, S., Garsky, V. M., Lai, M. T., Li, Y. M., Platchek, M., Register, R. B., Sardana, M. K., et al. (2001). The pro domain of beta-secretase does not confer strict zymogen-like properties but does assist proper folding of the protease domain. J Biol Chem 276, 10366-10373.
-
(2001)
J Biol Chem
, vol.276
, pp. 10366-10373
-
-
Shi, X.P.1
Chen, E.2
Yin, K.C.3
Na, S.4
Garsky, V.M.5
Lai, M.T.6
Li, Y.M.7
Platchek, M.8
Register, R.B.9
Sardana, M.K.10
-
69
-
-
0033613129
-
Cellular mechanisms of beta-amyloid production and secretion
-
Sinha, S., and Lieberburg, I. (1999). Cellular mechanisms of beta-amyloid production and secretion. Proc Natl Acad Sci U S A 96, 11049-11053.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 11049-11053
-
-
Sinha, S.1
Lieberburg, I.2
-
70
-
-
24644456470
-
Calcium dysregulation in Alzheimer's disease: Recent advances gained from genetically modified animals
-
Smith, I. F., Green, K. N., and LaFerla, F. M. (2005). Calcium dysregulation in Alzheimer's disease: recent advances gained from genetically modified animals. Cell Calcium 38, 427-437.
-
(2005)
Cell Calcium
, vol.38
, pp. 427-437
-
-
Smith, I.F.1
Green, K.N.2
LaFerla, F.M.3
-
71
-
-
23044445669
-
Regulation of NMDA receptor trafficking by amyloid-beta
-
Snyder, E. M., Nong, Y., Almeida, C. G., Paul, S., Moran, T., Choi, E. Y., Nairn, A. C., Salter, M. W., Lombroso, P. J., Gouras, G. K., and Greengard, P. (2005). Regulation of NMDA receptor trafficking by amyloid-beta. Nat Neurosci 8, 1051-1058.
-
(2005)
Nat Neurosci
, vol.8
, pp. 1051-1058
-
-
Snyder, E.M.1
Nong, Y.2
Almeida, C.G.3
Paul, S.4
Moran, T.5
Choi, E.Y.6
Nairn, A.C.7
Salter, M.W.8
Lombroso, P.J.9
Gouras, G.K.10
Greengard, P.11
-
73
-
-
0033615611
-
Hypoxic enhancement of quantal catecholamine secretion. Evidence for the involvement of amyloid beta-peptides
-
Taylor, S. C., Batten, T. F., and Peers, C. (1999). Hypoxic enhancement of quantal catecholamine secretion. Evidence for the involvement of amyloid beta-peptides. J Biol Chem 274, 31217-31222.
-
(1999)
J Biol Chem
, vol.274
, pp. 31217-31222
-
-
Taylor, S.C.1
Batten, T.F.2
Peers, C.3
-
74
-
-
0025987048
-
Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
-
Terry, R. D., Masliah, E., Salmon, D. P., Butters, N., DeTeresa, R., Hill, R., Hansen, L. A., and Katzman, R. (1991). Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol 30, 572-580.
-
(1991)
Ann Neurol
, vol.30
, pp. 572-580
-
-
Terry, R.D.1
Masliah, E.2
Salmon, D.P.3
Butters, N.4
DeTeresa, R.5
Hill, R.6
Hansen, L.A.7
Katzman, R.8
-
76
-
-
33748140720
-
2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations
-
2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations. Cell 126, 981-993.
-
(2006)
Cell
, vol.126
, pp. 981-993
-
-
Tu, H.1
Nelson, O.2
Bezprozvanny, A.3
Wang, Z.4
Lee, S.F.5
Hao, Y.H.6
Serneels, L.7
De Strooper, B.8
Yu, G.9
Bezprozvanny, I.10
-
78
-
-
0030785768
-
Decreased expression of N-methyl-D-aspartate receptor 1 messenger RNA in select regions of Alzheimer brain
-
Ulas, J., and Cotman, C. W. (1997). Decreased expression of N-methyl-D-aspartate receptor 1 messenger RNA in select regions of Alzheimer brain. Neuroscience 79, 973-982.
-
(1997)
Neuroscience
, vol.79
, pp. 973-982
-
-
Ulas, J.1
Cotman, C.W.2
-
79
-
-
4344566337
-
Calpain mediates calcium-induced activation of the erk1,2 MAPK pathway and cytoskeletal phosphorylation in neurons: Relevance to Alzheimer's disease
-
Veeranna, Kaji, T., Boland, B., Odrljin, T., Mohan, P., Basavarajappa, B. S., Peterhoff, C., Cataldo, A., Rudnicki, A., Amin, N., et al. (2004). Calpain mediates calcium-induced activation of the erk1,2 MAPK pathway and cytoskeletal phosphorylation in neurons: relevance to Alzheimer's disease. Am J Pathol 165, 795-805.
-
(2004)
Am J Pathol
, vol.165
, pp. 795-805
-
-
Veeranna Kaji, T.1
Boland, B.2
Odrljin, T.3
Mohan, P.4
Basavarajappa, B.S.5
Peterhoff, C.6
Cataldo, A.7
Rudnicki, A.8
Amin, N.9
-
80
-
-
14944378094
-
Certain inhibitors of synthetic amyloid beta-peptide (Abeta) fibrillogenesis block oligomerization of natural Abeta and thereby rescue long-term potentiation
-
Walsh, D. M., Townsend, M., Podlisny, M. B., Shankar, G. M., Fadeeva, J. V., El Agnaf, O., Hartley, D. M., and Selkoe, D. J. (2005). Certain inhibitors of synthetic amyloid beta-peptide (Abeta) fibrillogenesis block oligomerization of natural Abeta and thereby rescue long-term potentiation. J Neurosci 25, 2455-2462.
-
(2005)
J Neurosci
, vol.25
, pp. 2455-2462
-
-
Walsh, D.M.1
Townsend, M.2
Podlisny, M.B.3
Shankar, G.M.4
Fadeeva, J.V.5
El Agnaf, O.6
Hartley, D.M.7
Selkoe, D.J.8
-
81
-
-
4444222165
-
beta-Amyloid directly inhibits human alpha4beta2-nicotinic acetylcholine receptors heterologously expressed in human SH-EP1 cells
-
Wu, J., Kuo, Y. P., George, A. A., Xu, L., Hu, J., and Lukas, R. J. (2004). beta-Amyloid directly inhibits human alpha4beta2-nicotinic acetylcholine receptors heterologously expressed in human SH-EP1 cells. J Biol Chem 279, 37842-37851.
-
(2004)
J Biol Chem
, vol.279
, pp. 37842-37851
-
-
Wu, J.1
Kuo, Y.P.2
George, A.A.3
Xu, L.4
Hu, J.5
Lukas, R.J.6
-
82
-
-
10044293958
-
Calcium channel blockers and risk of AD: The Baltimore Longitudinal Study of Aging
-
Yasar, S., Corrada, M., Brookmeyer, R., and Kawas, C. (2005). Calcium channel blockers and risk of AD: the Baltimore Longitudinal Study of Aging. Neurobiol Aging 26, 157-163.
-
(2005)
Neurobiol Aging
, vol.26
, pp. 157-163
-
-
Yasar, S.1
Corrada, M.2
Brookmeyer, R.3
Kawas, C.4
-
83
-
-
3543060658
-
Amyloid beta-protein induced electrophysiological changes are dependent on aggregation state: N-methyl-D-aspartate (NMDA) versus non-NMDA receptor/channel activation
-
Ye, C., Walsh, D. M., Selkoe, D. J., and Hartley, D. M. (2004). Amyloid beta-protein induced electrophysiological changes are dependent on aggregation state: N-methyl-D-aspartate (NMDA) versus non-NMDA receptor/channel activation. Neurosci Lett 366, 320-325.
-
(2004)
Neurosci Lett
, vol.366
, pp. 320-325
-
-
Ye, C.1
Walsh, D.M.2
Selkoe, D.J.3
Hartley, D.M.4
-
84
-
-
0033712477
-
Presenilin-mediated modulation of capacitative calcium entry
-
Yoo, A. S., Cheng, I., Chung, S., Grenfell, T. Z., Lee, H., Pack-Chung, E., Handler, M., Shen, J., Xia, W., Tesco, G., et al. (2000). Presenilin-mediated modulation of capacitative calcium entry. Neuron 27, 561-572.
-
(2000)
Neuron
, vol.27
, pp. 561-572
-
-
Yoo, A.S.1
Cheng, I.2
Chung, S.3
Grenfell, T.Z.4
Lee, H.5
Pack-Chung, E.6
Handler, M.7
Shen, J.8
Xia, W.9
Tesco, G.10
-
85
-
-
0023823738
-
Decreased brain [3H]inositol 1,4,5- trisphosphate binding in Alzheimer's disease
-
Young, L. T., Kish, S. J., Li, P. P., and Warsh, J. J. (1988). Decreased brain [3H]inositol 1,4,5- trisphosphate binding in Alzheimer's disease. Neurosci Lett 94, 198-202.
-
(1988)
Neurosci Lett
, vol.94
, pp. 198-202
-
-
Young, L.T.1
Kish, S.J.2
Li, P.P.3
Warsh, J.J.4
|