-
1
-
-
36049045964
-
-
Alzheimer's Association, online] Accessed on March 1st, 2007. URL
-
Alzheimer's Association. 2007. Alzheimer's Facts and Figures." [online] Accessed on March 1st, 2007. URL: http://www.alz.org/ alzheimers_disease_alzheimer_statistics.asp.
-
(2007)
Alzheimer's Facts and Figures
-
-
-
2
-
-
28844456475
-
The development of anti-amyloid therapy for Alzheimer's disease: From secretase modulators to polymerisation inhibitors
-
Aisen PS. 2005. The development of anti-amyloid therapy for Alzheimer's disease: from secretase modulators to polymerisation inhibitors. CNS Drugs, 19(12):989-96.
-
(2005)
CNS Drugs
, vol.19
, Issue.12
, pp. 989-996
-
-
Aisen, P.S.1
-
3
-
-
0033761778
-
Functional triads consisting of ryanodine receptors, Ca(2+) channels, and Ca(2+)-activated K(+) channels in bullfrog sympathetic neurons. Plastic modulation of action potential
-
Akita T, Kuba K. 2000. Functional triads consisting of ryanodine receptors, Ca(2+) channels, and Ca(2+)-activated K(+) channels in bullfrog sympathetic neurons. Plastic modulation of action potential. J Gen Physiol, 116(5):697-720.
-
(2000)
J Gen Physiol
, vol.116
, Issue.5
, pp. 697-720
-
-
Akita, T.1
Kuba, K.2
-
4
-
-
1242269712
-
Architecture of the Alzheimer's A beta P ion channel pore
-
Arispe N. 2004. Architecture of the Alzheimer's A beta P ion channel pore. J Membr Biol, 197(1):33-48.
-
(2004)
J Membr Biol
, vol.197
, Issue.1
, pp. 33-48
-
-
Arispe, N.1
-
5
-
-
0027490362
-
Giant multilevel cation channels formed by Alzheimer disease amyloid beta-protein (A beta P-(1-40)] in bilayer membranes
-
Arispe N, Pollard HB, et al. 1993. Giant multilevel cation channels formed by Alzheimer disease amyloid beta-protein (A beta P-(1-40)] in bilayer membranes. Proc Natl Acad Sci U S A, 90(22):10573-7.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, Issue.22
, pp. 10573-10577
-
-
Arispe, N.1
Pollard, H.B.2
-
6
-
-
0029670048
-
2+ interaction with Alzheimer amyloid beta protein calcium channels
-
2+ interaction with Alzheimer amyloid beta protein calcium channels. Proc Natl Acad Sci U S A, 93(4):1710-5.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, Issue.4
, pp. 1710-1715
-
-
Arispe, N.1
Pollard, H.B.2
-
7
-
-
7244236320
-
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
-
Arrasate M, Mitra S, et al. 2004. Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death. Nature, 431(7010):805-10.
-
(2004)
Nature
, vol.431
, Issue.7010
, pp. 805-810
-
-
Arrasate, M.1
Mitra, S.2
-
8
-
-
1842558602
-
Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury
-
Arundine M, Tymianski M. 2004. Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury. Cell Mol Life Sci, 61(6):657-69.
-
(2004)
Cell Mol Life Sci
, vol.61
, Issue.6
, pp. 657-669
-
-
Arundine, M.1
Tymianski, M.2
-
9
-
-
0035997249
-
Senile plaque composition and posttranslational modification of amyloid-beta peptide and associated proteins
-
Atwood CS, Martins RN, et al. 2002. Senile plaque composition and posttranslational modification of amyloid-beta peptide and associated proteins. Peptides, 23(7):1343-50.
-
(2002)
Peptides
, vol.23
, Issue.7
, pp. 1343-1350
-
-
Atwood, C.S.1
Martins, R.N.2
-
10
-
-
0141791435
-
2+-induced modification of the kinetics of A beta(1-42) channels
-
2+-induced modification of the kinetics of A beta(1-42) channels. Am J Physiol Cell Physiol, 285(4): C873-80.
-
(2003)
Am J Physiol Cell Physiol
, vol.285
, Issue.4
-
-
Bahadi, R.1
Farrelly, P.V.2
-
11
-
-
0028207907
-
Amyloid beta peptide induces necrosis rather than apoptosis
-
Behl C, Davis JB, et al. 1994. Amyloid beta peptide induces necrosis rather than apoptosis. Brain Res, 645(1-2):253-64.
-
(1994)
Brain Res
, vol.645
, Issue.1-2
, pp. 253-264
-
-
Behl, C.1
Davis, J.B.2
-
12
-
-
0034017867
-
The voltage sensor in voltage-dependent ion channels
-
Bezanilla F. 2000. The voltage sensor in voltage-dependent ion channels. Physiol Rev, 80(2):555-92.
-
(2000)
Physiol Rev
, vol.80
, Issue.2
, pp. 555-592
-
-
Bezanilla, F.1
-
13
-
-
0034087948
-
Fresh and globular amyloid beta protein (1-42) induces rapid cellular degeneration: Evidence for AbetaP channel-mediated cellular toxicity
-
Bhatia R, Lin H, et al. 2000. Fresh and globular amyloid beta protein (1-42) induces rapid cellular degeneration: evidence for AbetaP channel-mediated cellular toxicity. Faseb J, 14(9):1233-43.
-
(2000)
Faseb J
, vol.14
, Issue.9
, pp. 1233-1243
-
-
Bhatia, R.1
Lin, H.2
-
14
-
-
0014313861
-
The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects
-
Blessed G, Tomlinson BE, et al. 1968. The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. Br J Psychiatry, 114(512):797-811.
-
(1968)
Br J Psychiatry
, vol.114
, Issue.512
, pp. 797-811
-
-
Blessed, G.1
Tomlinson, B.E.2
-
15
-
-
34249018606
-
2+ homeostasis in peripheral neurones: Implications for changes in function
-
2+ homeostasis in peripheral neurones: implications for changes in function. Aging Cell, 6(3):285-96.
-
(2007)
Aging Cell
, vol.6
, Issue.3
, pp. 285-296
-
-
Buchholz, J.N.1
Behringer, E.J.2
-
16
-
-
16244404961
-
2+ buffers and synaptic efficacy
-
2+ buffers and synaptic efficacy. Cell Calcium, 37(5):489-95.
-
(2005)
Cell Calcium
, vol.37
, Issue.5
, pp. 489-495
-
-
Burnashev, N.1
Rozov, A.2
-
17
-
-
0032420558
-
2+ channels and their role in neurotransmitter release
-
2+ channels and their role in neurotransmitter release. Cell Calcium, 24(5-6):307-23.
-
(1998)
Cell Calcium
, vol.24
, Issue.5-6
, pp. 307-323
-
-
Catterall, W.A.1
-
18
-
-
0037551741
-
Protofibrils, pores, fibrils, and neurodegeneration: Separating the responsible protein aggregates from the innocent bystanders
-
Caughey B, Lansbury PT. 2003. Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders. Annu Rev Neurosci, 26:267-98.
-
(2003)
Annu Rev Neurosci
, vol.26
, pp. 267-298
-
-
Caughey, B.1
Lansbury, P.T.2
-
19
-
-
0030769092
-
Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells
-
Cook DG, Forman MS, et al. 1997. Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells. Nat Med, 3(9):1021-3.
-
(1997)
Nat Med
, vol.3
, Issue.9
, pp. 1021-1023
-
-
Cook, D.G.1
Forman, M.S.2
-
20
-
-
0036884184
-
Erratic expression of DNA polymerases by beta-amyloid causes neuronal death
-
Copani A, Sortino MA, et al. 2002. Erratic expression of DNA polymerases by beta-amyloid causes neuronal death. Faseb J, 16(14):2006-8.
-
(2002)
Faseb J
, vol.16
, Issue.14
, pp. 2006-2008
-
-
Copani, A.1
Sortino, M.A.2
-
21
-
-
4444262625
-
Cdk5 deregulation in the pathogenesis of Alzheimer's disease
-
Cruz JC, Tsai LH. 2004. Cdk5 deregulation in the pathogenesis of Alzheimer's disease. Trends Mol Med, 10(9):452-8.
-
(2004)
Trends Mol Med
, vol.10
, Issue.9
, pp. 452-458
-
-
Cruz, J.C.1
Tsai, L.H.2
-
22
-
-
0037220599
-
Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils
-
De Ferrari GV, Charon MA, et al. 2003. Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils. Mol Psychiatry, 8(2):195-208.
-
(2003)
Mol Psychiatry
, vol.8
, Issue.2
, pp. 195-208
-
-
De Ferrari, G.V.1
Charon, M.A.2
-
23
-
-
0034910509
-
Death receptor-induced apoptotic and necrotic cell death: Differential role of caspases and mitochondria
-
Denecker G, Vercammen D, et al. 2001. Death receptor-induced apoptotic and necrotic cell death: differential role of caspases and mitochondria. Cell Death Differ, 9(8):829-40.
-
(2001)
Cell Death Differ
, vol.9
, Issue.8
, pp. 829-840
-
-
Denecker, G.1
Vercammen, D.2
-
24
-
-
0030669036
-
The pathogenesis of senile plaques
-
Dickson DW 1997. The pathogenesis of senile plaques. J Neuropathol Exp Neurol, 56(4):321-39.
-
(1997)
J Neuropathol Exp Neurol
, vol.56
, Issue.4
, pp. 321-339
-
-
Dickson, D.W.1
-
25
-
-
0027944284
-
Theoretical models of the ion channel structure of amyloid beta-protein
-
Durell SP, Guy HR, et al. 1994. Theoretical models of the ion channel structure of amyloid beta-protein. Biophys J, 67(6):2137-45.
-
(1994)
Biophys J
, vol.67
, Issue.6
, pp. 2137-2145
-
-
Durell, S.P.1
Guy, H.R.2
-
26
-
-
0035029341
-
Alzheimer's disease-like alterations in peripheral cells from presenilin-1 transgenic mice
-
Eckert A, Schindowski K, et al. 2001. Alzheimer's disease-like alterations in peripheral cells from presenilin-1 transgenic mice. Neurobiol Dis, 8(2):331-42.
-
(2001)
Neurobiol Dis
, vol.8
, Issue.2
, pp. 331-342
-
-
Eckert, A.1
Schindowski, K.2
-
27
-
-
0030915587
-
Intracellular ATP levels determine cell death fate by apoptosis or necrosis
-
Eguchi Y, Shimizu S, et al. 1997. Intracellular ATP levels determine cell death fate by apoptosis or necrosis. Cancer Res, 57(10):1835-40.
-
(1997)
Cancer Res
, vol.57
, Issue.10
, pp. 1835-1840
-
-
Eguchi, Y.1
Shimizu, S.2
-
29
-
-
33751510212
-
Amyloid ion channels: A porous argument or a thin excuse?
-
Eliezer D. 2006. "Amyloid ion channels: a porous argument or a thin excuse?" J Gen Physiol, 128(6):631-3.
-
(2006)
J Gen Physiol
, vol.128
, Issue.6
, pp. 631-633
-
-
Eliezer, D.1
-
30
-
-
0032459161
-
Benzodiazepines may have protective effects against Alzheimer disease
-
Fastbom J, Forsell Y, et al. 1998. Benzodiazepines may have protective effects against Alzheimer disease. Alzheimer Dis Assoc Disord, 12(1):14-7.
-
(1998)
Alzheimer Dis Assoc Disord
, vol.12
, Issue.1
, pp. 14-17
-
-
Fastbom, J.1
Forsell, Y.2
-
31
-
-
1542284022
-
Intra- and extracellular Abeta and PHF in clinically evaluated cases of Alzheimer's disease
-
Fernandez-Vizarra P, Fernandez AP, et al. 2004. Intra- and extracellular Abeta and PHF in clinically evaluated cases of Alzheimer's disease. Histol Histopathol, 19(3):823-44.
-
(2004)
Histol Histopathol
, vol.19
, Issue.3
, pp. 823-844
-
-
Fernandez-Vizarra, P.1
Fernandez, A.P.2
-
32
-
-
0031014448
-
Ionic effects of the Alzheimer's disease beta-amyloid precursor protein and its metabolic fragments
-
Fraser S P, Suh YH, et al. 1997. Ionic effects of the Alzheimer's disease beta-amyloid precursor protein and its metabolic fragments: Trends Neurosci, 20(2):67-72.
-
(1997)
Trends Neurosci
, vol.20
, Issue.2
, pp. 67-72
-
-
Fraser, S.P.1
Suh, Y.H.2
-
33
-
-
85044705207
-
Molecule of the month. MPC-7869
-
Mar
-
Flurizan. 2005 Mar. Molecule of the month. MPC-7869. Drugs News Perspect, 18(2):141.
-
(2005)
Drugs News Perspect
, vol.18
, Issue.2
, pp. 141
-
-
Flurizan1
-
35
-
-
33745737686
-
Pharmacology of P2X channels
-
Gever JR, Cockayne DA, et al. 2006. Pharmacology of P2X channels. Pflugers Arch, 452(5):513-37.
-
(2006)
Pflugers Arch
, vol.452
, Issue.5
, pp. 513-537
-
-
Gever, J.R.1
Cockayne, D.A.2
-
36
-
-
21544438539
-
Stereoselective Inhibition of Amyloid Beta Peptide Secretion by LY450139, A Novel Furictional Gamma Secretase Inhibitor
-
Gitter BD, CD, Li W, Dieckman DK, Bender MH, Nissen JS, Mabry TE, Yin T, Boggs LN, McClure DB, Little SP, Johnstone EM, Audia JE, May PC, Hyslop PA. 2004. Stereoselective Inhibition of Amyloid Beta Peptide Secretion by LY450139, A Novel Furictional Gamma Secretase Inhibitor. Neurobiol Aging, 25(Suppl 2):S571.
-
(2004)
Neurobiol Aging
, vol.25
, Issue.SUPPL. 2
-
-
Gitter, B.D.1
CD, L.W.2
Dieckman, D.K.3
Bender, M.H.4
Nissen, J.S.5
Mabry, T.E.6
Yin, T.7
Boggs, L.N.8
McClure, D.B.9
Little, S.P.10
Johnstone, E.M.11
Audia, J.E.12
May, P.C.13
Hyslop, P.A.14
-
37
-
-
0021256895
-
Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
-
Glenner GG, Wong CW. 1984. Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun, 120(3):885-90.
-
(1984)
Biochem Biophys Res Commun
, vol.120
, Issue.3
, pp. 885-890
-
-
Glenner, G.G.1
Wong, C.W.2
-
38
-
-
0034718027
-
Biochemical detection of Abeta isoforms: Implications for pathogenesis, diagnosis, and treatment of Alzheimer's disease
-
Golde TE, Eckman CB, et al. 2000. Biochemical detection of Abeta isoforms: implications for pathogenesis, diagnosis, and treatment of Alzheimer's disease. Biochim Biophys Acta, 1502(1):172-87.
-
(2000)
Biochim Biophys Acta
, vol.1502
, Issue.1
, pp. 172-187
-
-
Golde, T.E.1
Eckman, C.B.2
-
39
-
-
0023037536
-
Isolation and partial characterization of neurofibrillary tangles and amyloid plaque core in Alzheimer's disease: Immumohistological studies
-
Gorevic PD, Goni F, et al. 1986. Isolation and partial characterization of neurofibrillary tangles and amyloid plaque core in Alzheimer's disease: immumohistological studies. J Neuropathol Exp Neurol, 45(6):647-64.
-
(1986)
J Neuropathol Exp Neurol
, vol.45
, Issue.6
, pp. 647-664
-
-
Gorevic, P.D.1
Goni, F.2
-
40
-
-
3142655729
-
Transgenic animal models of Alzheimer's disease and related disorders: Histopathology, behavior and therapy
-
Gotz J, Streffer JR, et al. 2004. Transgenic animal models of Alzheimer's disease and related disorders: histopathology, behavior and therapy. Mol Psychiatry, 9(7):664-83.
-
(2004)
Mol Psychiatry
, vol.9
, Issue.7
, pp. 664-683
-
-
Gotz, J.1
Streffer, J.R.2
-
41
-
-
0033622324
-
Intraneuronal Abeta42 accumulation in human brain
-
Gouras GK, Tsai J, et al. 2000. Intraneuronal Abeta42 accumulation in human brain. Am J Pathol, 156(1):15-20.
-
(2000)
Am J Pathol
, vol.156
, Issue.1
, pp. 15-20
-
-
Gouras, G.K.1
Tsai, J.2
-
42
-
-
0028915895
-
Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta 40 or A beta 42(43)
-
Gravina. SA, Ho L, et al. 1995. Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta 40 or A beta 42(43). J Biol Chem, 270(13):70134.
-
(1995)
J Biol Chem
, vol.270
, Issue.13
, pp. 70134
-
-
Gravina, S.A.1
Ho, L.2
-
43
-
-
0033582159
-
Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides
-
Greenfield JP, Tsai J, et al. 1999. Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides. Proc Natl Acad Sci USA, 96(2):742-7.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.2
, pp. 742-747
-
-
Greenfield, J.P.1
Tsai, J.2
-
44
-
-
0030888520
-
Calpains and calpastatin in SH-SY5Y neuroblastoma cells during retinoic acid-induced differentiation and neurite outgrowth: Comparison with the human brain calpain system
-
Grynspan F, Griffin WB, et al. 1997. Calpains and calpastatin in SH-SY5Y neuroblastoma cells during retinoic acid-induced differentiation and neurite outgrowth: comparison with the human brain calpain system. J Neurosci Res, 48(3):181-91.
-
(1997)
J Neurosci Res
, vol.48
, Issue.3
, pp. 181-191
-
-
Grynspan, F.1
Griffin, W.B.2
-
45
-
-
0033016172
-
Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice
-
Guo Q, Fu W, et al. 1999. Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice. Nat Med, 5(1):101-6.
-
(1999)
Nat Med
, vol.5
, Issue.1
, pp. 101-106
-
-
Guo, Q.1
Fu, W.2
-
46
-
-
0026735070
-
Targeting of cell-surface beta-amyloid precursor protein to lysosomes: Alternative processing into amyloid-bearing fragments
-
Haass C, Koo EH, et al. 1992. Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments. Nature, 357(6378):500-3.
-
(1992)
Nature
, vol.357
, Issue.6378
, pp. 500-503
-
-
Haass, C.1
Koo, E.H.2
-
47
-
-
0026646604
-
Amyloid beta-peptide is produced by cultured cells during normal metabolism
-
Haass C, Schlossmacher MG, et al. 1992. Amyloid beta-peptide is produced by cultured cells during normal metabolism. Nature, 359(6393):322-5.
-
(1992)
Nature
, vol.359
, Issue.6393
, pp. 322-325
-
-
Haass, C.1
Schlossmacher, M.G.2
-
48
-
-
0019441262
-
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
-
Hamill OP, Marty A, et al. 1981. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch, 391(2):85-100.
-
(1981)
Pflugers Arch
, vol.391
, Issue.2
, pp. 85-100
-
-
Hamill, O.P.1
Marty, A.2
-
49
-
-
0026597063
-
Alzheimer's disease: The amyloid cascade hypothesis
-
Hardy JA, Higgins GA. 1992. Alzheimer's disease: the amyloid cascade hypothesis. Science, 256(5054):184-5.
-
(1992)
Science
, vol.256
, Issue.5054
, pp. 184-185
-
-
Hardy, J.A.1
Higgins, G.A.2
-
50
-
-
0032517134
-
Mouse cortical neurones lacking APP show normal neurite outgrowth and survival responses in vitro
-
Harper SJ, Bilsland JG, et al. 1998. Mouse cortical neurones lacking APP show normal neurite outgrowth and survival responses in vitro. Neuroreport, 9(13):3053-8.
-
(1998)
Neuroreport
, vol.9
, Issue.13
, pp. 3053-3058
-
-
Harper, S.J.1
Bilsland, J.G.2
-
51
-
-
16244396752
-
Determinants of postsynaptic Ca2+ signaling in Purkinje neurons
-
Hartmann J, Konnerth A. 2005. Determinants of postsynaptic Ca2+ signaling in Purkinje neurons. Cell Calcium, 37(5):459-66.
-
(2005)
Cell Calcium
, vol.37
, Issue.5
, pp. 459-466
-
-
Hartmann, J.1
Konnerth, A.2
-
52
-
-
0030769091
-
Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides
-
Hartmann T, Bieger SC, et al. 1997. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat Med, 3(9):1016-20.
-
(1997)
Nat Med
, vol.3
, Issue.9
, pp. 1016-1020
-
-
Hartmann, T.1
Bieger, S.C.2
-
53
-
-
34247112490
-
Apolipoprotein receptor 2 and X11 alpha/ beta mediate apolipoprotein E-induced endocytosis of amyloid-beta precursor protein and beta-secretase, leading to amyloid-beta production
-
He X, Cooley K, et al. 2007. Apolipoprotein receptor 2 and X11 alpha/ beta mediate apolipoprotein E-induced endocytosis of amyloid-beta precursor protein and beta-secretase, leading to amyloid-beta production. J Neurosci, 27(15):4052-60.
-
(2007)
J Neurosci
, vol.27
, Issue.15
, pp. 4052-4060
-
-
He, X.1
Cooley, K.2
-
54
-
-
0033566369
-
Alzheimer amyloid abetal-42 channels: Effects of solvent, pH, and Congo Red
-
Hirakura Y, Lin MC, et al. 1999. Alzheimer amyloid abetal-42 channels: effects of solvent, pH, and Congo Red. J Neurosci Res, 57(4):458-66.
-
(1999)
J Neurosci Res
, vol.57
, Issue.4
, pp. 458-466
-
-
Hirakura, Y.1
Lin, M.C.2
-
57
-
-
0034737829
-
Antioxidants prevent amyloid peptide-induced apoptosis and alteration of calcium homeostasis in cultured cortical neurons
-
Huang HM, Ou HC, et al. 2000. Antioxidants prevent amyloid peptide-induced apoptosis and alteration of calcium homeostasis in cultured cortical neurons. Life Sci, 66(19):1879-92.
-
(2000)
Life Sci
, vol.66
, Issue.19
, pp. 1879-1892
-
-
Huang, H.M.1
Ou, H.C.2
-
58
-
-
0034629320
-
Blockage of amyloid beta peptide-induced cytosolic free calcium by fullerenol-1, carboxylate C60 in PC12 cells
-
Huang HM, Ou HC, et al. 2000. Blockage of amyloid beta peptide-induced cytosolic free calcium by fullerenol-1, carboxylate C60 in PC12 cells. Life Sci, 66(16):1525-33.
-
(2000)
Life Sci
, vol.66
, Issue.16
, pp. 1525-1533
-
-
Huang, H.M.1
Ou, H.C.2
-
59
-
-
0028169925
-
Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: Evidence that an initially deposited species is A beta 42(43)
-
Iwatsubo T, Odaka A, et al. 1994. Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43). Neuron, 13(1):45-53.
-
(1994)
Neuron
, vol.13
, Issue.1
, pp. 45-53
-
-
Iwatsubo, T.1
Odaka, A.2
-
60
-
-
0027425060
-
The C-terminus of the beta protein is critical in amyloidogenesis
-
Jarrett JT, Berger EP, et al. 1993. The C-terminus of the beta protein is critical in amyloidogenesis. Ann N Y Acad Sci, 695:144-8.
-
(1993)
Ann N Y Acad Sci
, vol.695
, pp. 144-148
-
-
Jarrett, J.T.1
Berger, E.P.2
-
61
-
-
0027258525
-
The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease
-
Jarrett JT, Berger EP, et al. 1993. The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease. Biochemistry, 32(18):4693-7.
-
(1993)
Biochemistry
, vol.32
, Issue.18
, pp. 4693-4697
-
-
Jarrett, J.T.1
Berger, E.P.2
-
62
-
-
0942276796
-
Induction of pro-apoptotic calsenilin/DREAM/ KChIP3 in Alzheimer's disease and cultured neurons after amyloid-beta exposure
-
Jo DG, Lee JY, et al. 2004. Induction of pro-apoptotic calsenilin/DREAM/ KChIP3 in Alzheimer's disease and cultured neurons after amyloid-beta exposure. J Neurochem, 88(3):604-11.
-
(2004)
J Neurochem
, vol.88
, Issue.3
, pp. 604-611
-
-
Jo, D.G.1
Lee, J.Y.2
-
63
-
-
0030749259
-
Giga-ohm. seals on intracellular membranes: A technique for studying intracellular ion channels in intact cells
-
Jonas EA, Knox RJ, et al. 1997. Giga-ohm. seals on intracellular membranes: a technique for studying intracellular ion channels in intact cells. Neuron, 19(1):7-13.
-
(1997)
Neuron
, vol.19
, Issue.1
, pp. 7-13
-
-
Jonas, E.A.1
Knox, R.J.2
-
64
-
-
0344672942
-
APP processing and synaptic function
-
Kamenetz F, Tomita T, et al. 2003. APP processing and synaptic function. Neuron, 37(6):925-37.
-
(2003)
Neuron
, vol.37
, Issue.6
, pp. 925-937
-
-
Kamenetz, F.1
Tomita, T.2
-
65
-
-
0025911018
-
Advances in Alzheimer's disease
-
Katzman R, Saitoh T. 1991. Advances in Alzheimer's disease. Faseb J, 5(3):278-86.
-
(1991)
Faseb J
, vol.5
, Issue.3
, pp. 278-286
-
-
Katzman, R.1
Saitoh, T.2
-
66
-
-
0030966536
-
2+)-sensitive, cation-selective channels across excised membrane patches from hypothalamic neurons
-
2+)-sensitive, cation-selective channels across excised membrane patches from hypothalamic neurons. Biophys J, 73(1):67-75.
-
(1997)
Biophys J
, vol.73
, Issue.1
, pp. 67-75
-
-
Kawahara, M.1
Arispe, N.2
-
67
-
-
0026630006
-
Patch clamp techniques to study ion channels from organelles
-
Keller BU, Hedrich R. 1992. Patch clamp techniques to study ion channels from organelles. Methods Enzymol, 207:673-81.
-
(1992)
Methods Enzymol
, vol.207
, pp. 673-681
-
-
Keller, B.U.1
Hedrich, R.2
-
68
-
-
2542455537
-
Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease
-
Klein WL, Stine WB Jr, et al. 2004. Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease. Neurobiol Aging, 25(5):569-80.
-
(2004)
Neurobiol Aging
, vol.25
, Issue.5
, pp. 569-580
-
-
Klein, W.L.1
Stine Jr, W.B.2
-
69
-
-
0025110182
-
Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage
-
Koh JY, Yang LL, et al. 1990. Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage. Brain Res, 533(2):315-20.
-
(1990)
Brain Res
, vol.533
, Issue.2
, pp. 315-320
-
-
Koh, J.Y.1
Yang, L.L.2
-
70
-
-
0028276801
-
Evidence that production and release of amyloid beta-protein involves the endocytic pathway
-
Koo EH, Squazzo SL. 1994. Evidence that production and release of amyloid beta-protein involves the endocytic pathway. J Biol Chem, 269(26):17386-9.
-
(1994)
J Biol Chem
, vol.269
, Issue.26
, pp. 17386-17389
-
-
Koo, E.H.1
Squazzo, S.L.2
-
71
-
-
0025879957
-
An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P
-
Kowall NW, Beal MF, et al. 1991. An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P. Proc Natl Acad Sci USA, 88(16):7247-51.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, Issue.16
, pp. 7247-7251
-
-
Kowall, N.W.1
Beal, M.F.2
-
72
-
-
0030900980
-
Intracellular adenosine triphosphate (ATP) concentration: A switch in the decision between apoptosis and necrosis
-
Leist M, Single B, et al. 1997. Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis. J Exp Med, 185(8):1481-6.
-
(1997)
J Exp Med
, vol.185
, Issue.8
, pp. 1481-1486
-
-
Leist, M.1
Single, B.2
-
73
-
-
26844574739
-
NMDA receptor activation inhibits alpha-secretase and promotes neuronal amyloid-beta production
-
Lesne S, Ali C, et al. 2005. NMDA receptor activation inhibits alpha-secretase and promotes neuronal amyloid-beta production. J Neurosci, 25(41):9367-77.
-
(2005)
J Neurosci
, vol.25
, Issue.41
, pp. 9367-9377
-
-
Lesne, S.1
Ali, C.2
-
74
-
-
31044433933
-
Anti-Abeta42- and anti-Abeta40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model
-
Levites Y, Das P, et al. 2006. Anti-Abeta42- and anti-Abeta40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model. J Clin Invest, 116(1):193-201.
-
(2006)
J Clin Invest
, vol.116
, Issue.1
, pp. 193-201
-
-
Levites, Y.1
Das, P.2
-
75
-
-
0035159553
-
Amyloid beta protein forms ion channels: Implications for Alzheimer's disease pathophysiology
-
Lin H, Bhatia R, et al. 2001. Amyloid beta protein forms ion channels: implications for Alzheimer's disease pathophysiology. Faseb J, 15(13):2433-44.
-
(2001)
Faseb J
, vol.15
, Issue.13
, pp. 2433-2444
-
-
Lin, H.1
Bhatia, R.2
-
76
-
-
0033600590
-
2+-sensitive channel in reconstituted lipid vesicles
-
2+-sensitive channel in reconstituted lipid vesicles. Biochemistry, 38(34):11189-96.
-
(1999)
Biochemistry
, vol.38
, Issue.34
, pp. 11189-11196
-
-
Lin, H.1
Zhu, Y.J.2
-
77
-
-
0034652309
-
Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein
-
Lin X, Koelsch G, et al. 2000. Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein. Proc Natl A cad Sci USA, 97(4):1456-60.
-
(2000)
Proc Natl A cad Sci USA
, vol.97
, Issue.4
, pp. 1456-1460
-
-
Lin, X.1
Koelsch, G.2
-
78
-
-
0028172886
-
Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red
-
Lorenzo A, Yankner BA. 1994. Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red. Proc Natl Acad Sci U S A, 91(25):12243-7.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, Issue.25
, pp. 12243-12247
-
-
Lorenzo, A.1
Yankner, B.A.2
-
79
-
-
0029884821
-
Atypical amyloid (A beta) deposition in the cerebellum in Alzheimer's disease: An immunohistochemical study using end-specific A beta monoclonal antibodies
-
Mann DM, Iwatsubo T, et al. 1996. Atypical amyloid (A beta) deposition in the cerebellum in Alzheimer's disease: an immunohistochemical study using end-specific A beta monoclonal antibodies. Acta Neuropathol (Berl), 91(6):647-53.
-
(1996)
Acta Neuropathol (Berl)
, vol.91
, Issue.6
, pp. 647-653
-
-
Mann, D.M.1
Iwatsubo, T.2
-
80
-
-
0032007328
-
Modification of ion homeostasis by lipid peroxidation: Roles in neuronal degeneration and adaptive plasticity
-
Mattson MP. 1998. Modification of ion homeostasis by lipid peroxidation: roles in neuronal degeneration and adaptive plasticity. Trends Neurosci, 21(2):53-7.
-
(1998)
Trends Neurosci
, vol.21
, Issue.2
, pp. 53-57
-
-
Mattson, M.P.1
-
81
-
-
34249092704
-
Calcium and neurodegeneration
-
Mattson MP. 2007. Calcium and neurodegeneration. Aging Cell, 6(3):337-50.
-
(2007)
Aging Cell
, vol.6
, Issue.3
, pp. 337-350
-
-
Mattson, M.P.1
-
82
-
-
0026570528
-
beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
-
Mattson MP, Cheng B, et al. 1992. beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J Neurosci, 12(2):376-89.
-
(1992)
J Neurosci
, vol.12
, Issue.2
, pp. 376-389
-
-
Mattson, M.P.1
Cheng, B.2
-
83
-
-
0027297138
-
Calcium-destabilizing and neuro-degenerative effects of aggregated beta-amyloid peptide are attenuated by basic FGF
-
Mattson MP, Tomaselli KJ, et al. 1993. Calcium-destabilizing and neuro-degenerative effects of aggregated beta-amyloid peptide are attenuated by basic FGF. Brain Res, 621(1):35-49.
-
(1993)
Brain Res
, vol.621
, Issue.1
, pp. 35-49
-
-
Mattson, M.P.1
Tomaselli, K.J.2
-
84
-
-
0025057071
-
Ion channels in the nuclear envelope
-
Mazzanti M, DeFelice LJ, et al. 1990. Ion channels in the nuclear envelope. Nature, 343(6260):764-7.
-
(1990)
Nature
, vol.343
, Issue.6260
, pp. 764-767
-
-
Mazzanti, M.1
DeFelice, L.J.2
-
85
-
-
33645573049
-
Apoptosis and necrosis: A review for surgeons
-
5 3-68
-
McHugh P, Turina M. 2006. Apoptosis and necrosis: a review for surgeons. Surg Infect (Larchmt), 7(1):5 3-68.
-
(2006)
Surg Infect (Larchmt)
, vol.7
, Issue.1
-
-
McHugh, P.1
Turina, M.2
-
86
-
-
0035907123
-
200 1. Amyloid beta protein 1-40 and 1-42 levels in matched cerebrospinal fluid and plasma ftom patients with Alzheimer disease
-
Mehta PD, Pirttila T, et al. 200 1. Amyloid beta protein 1-40 and 1-42 levels in matched cerebrospinal fluid and plasma ftom patients with Alzheimer disease. Neurosci Lett, 304(1-2):102-6.
-
Neurosci Lett
, vol.304
, Issue.1-2
, pp. 102-106
-
-
Mehta, P.D.1
Pirttila, T.2
-
87
-
-
0034672942
-
The role of oxidative stress in the toxicity induced by amyloid beta-peptide in Alzheimer's disease
-
Miranda S, Opazo C, et al. 2000. The role of oxidative stress in the toxicity induced by amyloid beta-peptide in Alzheimer's disease. Prog Neurobiol, 62(6):633-48.
-
(2000)
Prog Neurobiol
, vol.62
, Issue.6
, pp. 633-648
-
-
Miranda, S.1
Opazo, C.2
-
88
-
-
11844260044
-
Structure and function of amyloid in Alzheimer's disease
-
3 23-49
-
Morgan C, Colombres M, et al. 2004. Structure and function of amyloid in Alzheimer's disease. Prog Neurobiol, 74(6):3 23-49.
-
(2004)
Prog Neurobiol
, vol.74
, Issue.6
-
-
Morgan, C.1
Colombres, M.2
-
89
-
-
0025629986
-
Genetics and biology of the Alzheimer amyloid precursor
-
Neve RL, Dawes LR, et al. 1990. Genetics and biology of the Alzheimer amyloid precursor. Prog Brain Res, 86:257-67.
-
(1990)
Prog Brain Res
, vol.86
, pp. 257-267
-
-
Neve, R.L.1
Dawes, L.R.2
-
90
-
-
33749521100
-
Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: Potential factors in amyloid plaque formation
-
Oakley H, Cole SL, et al. 2006. Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation. J Neurosci, 26(40):10129-40.
-
(2006)
J Neurosci
, vol.26
, Issue.40
, pp. 10129-10140
-
-
Oakley, H.1
Cole, S.L.2
-
91
-
-
0042697305
-
Triple-transgenic model of Alzheimer's disease with plaques and tangles: Intracellular Abeta and synaptic dysfunction
-
Oddo S, Caccarno A, et al. 2003. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron, 39(3):409-21.
-
(2003)
Neuron
, vol.39
, Issue.3
, pp. 409-421
-
-
Oddo, S.1
Caccarno, A.2
-
92
-
-
0029860523
-
Amyloid beta peptide of Alzheimer's disease downregulates Bel-2 and upregulates bax expression in human neurons
-
Paradis E, Douillard H, et al. 1996. Amyloid beta peptide of Alzheimer's disease downregulates Bel-2 and upregulates bax expression in human neurons. J Neurosci, 16(23):7533-9.
-
(1996)
J Neurosci
, vol.16
, Issue.23
, pp. 7533-7539
-
-
Paradis, E.1
Douillard, H.2
-
93
-
-
33746809372
-
Physiological roles for amyloid beta peptides
-
Pearson HA, Peers C. 2006. Physiological roles for amyloid beta peptides. J Physiol, 575(Pt 1):5-10.
-
(2006)
J Physiol
, vol.575
, Issue.PART 1
, pp. 5-10
-
-
Pearson, H.A.1
Peers, C.2
-
94
-
-
0027447286
-
Neurodegeneration induced by beta-amyloid peptides in vitro: The role of peptide assembly state
-
Pike CJ, Burdick D, et al. 1993. Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state. J Neurosci, 13(4):1676-87.
-
(1993)
J Neurosci
, vol.13
, Issue.4
, pp. 1676-1687
-
-
Pike, C.J.1
Burdick, D.2
-
95
-
-
0038045587
-
The production of amyloid beta peptide is a critical requirement for the viability of central neurons
-
Plant LD, Boyle JP, et al. 2003. The production of amyloid beta peptide is a critical requirement for the viability of central neurons. J Neurosci, 23(13):5531-5.
-
(2003)
J Neurosci
, vol.23
, Issue.13
, pp. 5531-5535
-
-
Plant, L.D.1
Boyle, J.P.2
-
96
-
-
0032536512
-
Amyloid beta protein increases Ca2+ currents in rat cerebellar granule neurones
-
Price SA, Held B, et al. 1998. Amyloid beta protein increases Ca2+ currents in rat cerebellar granule neurones. Neuroreport, 9(3):539-45.
-
(1998)
Neuroreport
, vol.9
, Issue.3
, pp. 539-545
-
-
Price, S.A.1
Held, B.2
-
97
-
-
0037195424
-
2+ channel currents in primary cultures of rat cortical neurones by amyloid beta protein (1-40) is dependent on solubility status
-
2+ channel currents in primary cultures of rat cortical neurones by amyloid beta protein (1-40) is dependent on solubility status. Brain Res, 956(2):254-61.
-
(2002)
Brain Res
, vol.956
, Issue.2
, pp. 254-261
-
-
Ramsden, M.1
Henderson, Z.2
-
98
-
-
2442647903
-
Acetylcholinesterase-Abeta complexes are more toxic than Abeta fibrils in rat hippocampus: Effect on rat beta-amyloid aggregation, laminin expression, reactive astrocytosis, and neuronal cell loss
-
Reyes AE, Chacon MA, et al. 2004. Acetylcholinesterase-Abeta complexes are more toxic than Abeta fibrils in rat hippocampus: effect on rat beta-amyloid aggregation, laminin expression, reactive astrocytosis, and neuronal cell loss. Am J Pathol, 164(6):2163-74.
-
(2004)
Am J Pathol
, vol.164
, Issue.6
, pp. 2163-2174
-
-
Reyes, A.E.1
Chacon, M.A.2
-
100
-
-
9444245809
-
Morphology and toxicity of Abeta-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease
-
Roher AE, Chaney MO, et al. 1996. Morphology and toxicity of Abeta-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease. J Biol Chem, 271(34):20631-5.
-
(1996)
J Biol Chem
, vol.271
, Issue.34
, pp. 20631-20635
-
-
Roher, A.E.1
Chaney, M.O.2
-
101
-
-
0032032493
-
Turnover of amyloid beta-protein in mouse brain and acute reduction of its level by phorbol. ester
-
Savage MJ, Trusko SP, et al. 1998. Turnover of amyloid beta-protein in mouse brain and acute reduction of its level by phorbol. ester. J Neurosci, 18(5):1743-52.
-
(1998)
J Neurosci
, vol.18
, Issue.5
, pp. 1743-1752
-
-
Savage, M.J.1
Trusko, S.P.2
-
102
-
-
12144288683
-
Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease
-
Schmitz C, Rutten BP, et al. 2004. Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease. Am J Pathol, 164(4):1495-502.
-
(2004)
Am J Pathol
, vol.164
, Issue.4
, pp. 1495-1502
-
-
Schmitz, C.1
Rutten, B.P.2
-
103
-
-
0035066332
-
Alzheimer's disease: Genes, proteins, and therapy
-
Selkoe DJ. 2001. Alzheimer's disease: genes, proteins, and therapy. Physiol Rev, 81(2):741-66.
-
(2001)
Physiol Rev
, vol.81
, Issue.2
, pp. 741-766
-
-
Selkoe, D.J.1
-
104
-
-
0035950225
-
Clearing the brain's amyloid cobwebs
-
Selkoe DJ. 2001. Clearing the brain's amyloid cobwebs. Neuron, 32(2):177-80.
-
(2001)
Neuron
, vol.32
, Issue.2
, pp. 177-180
-
-
Selkoe, D.J.1
-
105
-
-
0022654027
-
Isolation of low-molecular-weight proteins from amyloid plaque fibers in Alzheimer's disease
-
Selkoe DJ, Abraham CR, et al. 1986. Isolation of low-molecular-weight proteins from amyloid plaque fibers in Alzheimer's disease. J Neurochem, 46(6):1820-34.
-
(1986)
J Neurochem
, vol.46
, Issue.6
, pp. 1820-1834
-
-
Selkoe, D.J.1
Abraham, C.R.2
-
106
-
-
0027459686
-
Secretion of beta-amyloid precursor protein cleaved at the amino terminus of the beta-amyloid peptide
-
Seubert P, Oltersdorf T, et al. 1993. Secretion of beta-amyloid precursor protein cleaved at the amino terminus of the beta-amyloid peptide. Nature, 361(6409):260-3.
-
(1993)
Nature
, vol.361
, Issue.6409
, pp. 260-263
-
-
Seubert, P.1
Oltersdorf, T.2
-
107
-
-
33646485088
-
Early and late cytotoxic effects of external application of the Alzheimer's Abeta result from the initial formation and function of Abeta ion channels
-
Simakova O, Arispe NJ. 2006. Early and late cytotoxic effects of external application of the Alzheimer's Abeta result from the initial formation and function of Abeta ion channels. Biochemistry, 45(18):5907-15.
-
(2006)
Biochemistry
, vol.45
, Issue.18
, pp. 5907-5915
-
-
Simakova, O.1
Arispe, N.J.2
-
108
-
-
0031781642
-
Detection of a novel intraneuronal pool of insoluble amyloid beta protein that accumulates with time in culture
-
Skovronsky DM, Doms RW, et al. 1998. Detection of a novel intraneuronal pool of insoluble amyloid beta protein that accumulates with time in culture. J Cell Biol, 141(4):1031-9.
-
(1998)
J Cell Biol
, vol.141
, Issue.4
, pp. 1031-1039
-
-
Skovronsky, D.M.1
Doms, R.W.2
-
109
-
-
33751516396
-
Soluble amyloid oligomers increase bilayer conductance by altering dielectric structure
-
Sokolov Y, Kozak JA, et al. 2006. Soluble amyloid oligomers increase bilayer conductance by altering dielectric structure. J Gen Physiol, 128(6):637-47.
-
(2006)
J Gen Physiol
, vol.128
, Issue.6
, pp. 637-647
-
-
Sokolov, Y.1
Kozak, J.A.2
-
110
-
-
0032983536
-
Association of microglia with amyloid plaques in brains of APP23 transgenic mice
-
Stalder M, Phinney A, et al. 1999. Association of microglia with amyloid plaques in brains of APP23 transgenic mice. Am J Pathol, 154(6):1673-84.
-
(1999)
Am J Pathol
, vol.154
, Issue.6
, pp. 1673-1684
-
-
Stalder, M.1
Phinney, A.2
-
111
-
-
0031731261
-
Hypersensitivity to seizures in beta-amyloid precursor protein deficient mice
-
Steinbach JP, Muller U, et al. 1998. Hypersensitivity to seizures in beta-amyloid precursor protein deficient mice. Cell Death Differ, 5(10):858-66.
-
(1998)
Cell Death Differ
, vol.5
, Issue.10
, pp. 858-866
-
-
Steinbach, J.P.1
Muller, U.2
-
112
-
-
0036827031
-
Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology
-
Takahashi RH, Milner TA, et al. 2002. Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology. Am J Pathol, 161(5):1869-79.
-
(2002)
Am J Pathol
, vol.161
, Issue.5
, pp. 1869-1879
-
-
Takahashi, R.H.1
Milner, T.A.2
-
113
-
-
0028335794
-
Solution structure of residues 1-28 of the amyloid beta-peptide
-
Talafous J, Marcinowski KJ, et al. 1994. Solution structure of residues 1-28 of the amyloid beta-peptide. Biochemistry, 33(25):7788-96.
-
(1994)
Biochemistry
, vol.33
, Issue.25
, pp. 7788-7796
-
-
Talafous, J.1
Marcinowski, K.J.2
-
114
-
-
0037382957
-
H2O2 and 4-hydroxynonenal mediate amyloid beta-induced neuronal apoptosis by activating JNKs and p38MAPK
-
Tamagno E, Robino G, et al. 2003. H2O2 and 4-hydroxynonenal mediate amyloid beta-induced neuronal apoptosis by activating JNKs and p38MAPK. Exp Neurol, 180(2):144-55.
-
(2003)
Exp Neurol
, vol.180
, Issue.2
, pp. 144-155
-
-
Tamagno, E.1
Robino, G.2
-
115
-
-
0031149062
-
Amyloid beta protein 42(43) in cerebrospinal fluid of patients with Alzheimer's disease
-
Tamaoka A, Sawamura N, et al. 1997. Amyloid beta protein 42(43) in cerebrospinal fluid of patients with Alzheimer's disease. J Neurol Sci, 148(1):41-5.
-
(1997)
J Neurol Sci
, vol.148
, Issue.1
, pp. 41-45
-
-
Tamaoka, A.1
Sawamura, N.2
-
116
-
-
33947493213
-
Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: Minding the store
-
Thibault O, Gant JC, et al, 2007. Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: minding the store. Aging Cell, 6(3):307-17.
-
(2007)
Aging Cell
, vol.6
, Issue.3
, pp. 307-317
-
-
Thibault, O.1
Gant, J.C.2
-
117
-
-
0034526675
-
Parameters of calcium homeostasis in normal neuronal ageing
-
Toescu EC, Verkhratsky A. 2000. Parameters of calcium homeostasis in normal neuronal ageing. J Anat, 197 Pt 4:563-9.
-
(2000)
J Anat
, vol.197
, Issue.PART 4
, pp. 563-569
-
-
Toescu, E.C.1
Verkhratsky, A.2
-
118
-
-
0014326852
-
Observations on the brains of non-demented old people
-
Tomlinson BE, Blessed G, et al. 1968. Observations on the brains of non-demented old people. J Neurol Sci, 7(2):331-56.
-
(1968)
J Neurol Sci
, vol.7
, Issue.2
, pp. 331-356
-
-
Tomlinson, B.E.1
Blessed, G.2
-
119
-
-
0014851803
-
Observations on the brains of demented old people
-
Tomlinson BE, Blessed G, et al. 1970. Observations on the brains of demented old people. J Neurol Sci, 11 (3):205-42.
-
(1970)
J Neurol Sci
, vol.11
, Issue.3
, pp. 205-242
-
-
Tomlinson, B.E.1
Blessed, G.2
-
120
-
-
0031474418
-
Contribution of somal Lewy bodies to neuronal death
-
Tompkins MM, Hill WD. 1997. Contribution of somal Lewy bodies to neuronal death. Brain Res, 775(1-2):24-9.
-
(1997)
Brain Res
, vol.775
, Issue.1-2
, pp. 24-29
-
-
Tompkins, M.M.1
Hill, W.D.2
-
121
-
-
0029664624
-
Amyloids beta40 and beta42 are generated intracellularly in cultured human neurons and their secretion increases with maturation
-
Turner RS, Suzuki N, et al. 1996. Amyloids beta40 and beta42 are generated intracellularly in cultured human neurons and their secretion increases with maturation. J Biol Chem, 271(15):8966-70.
-
(1996)
J Biol Chem
, vol.271
, Issue.15
, pp. 8966-8970
-
-
Turner, R.S.1
Suzuki, N.2
-
122
-
-
0037195163
-
Neurotoxic effects of thioflavin S-positive amyloid deposits in transgenic mice and Alzheimer's disease
-
Urbanc B, Cruz L, et al. 2002. Neurotoxic effects of thioflavin S-positive amyloid deposits in transgenic mice and Alzheimer's disease. Proc Natl Acad Sci U S A, 99(22):13990-5.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.22
, pp. 13990-13995
-
-
Urbanc, B.1
Cruz, L.2
-
123
-
-
24044541048
-
Advancing age alters rapid and spontaneous refilling of caffeine-sensitive calcium stores in sympathetic superior cervical ganglion cells
-
Vanterpool CK, Pearce WJ, et al. 2005. Advancing age alters rapid and spontaneous refilling of caffeine-sensitive calcium stores in sympathetic superior cervical ganglion cells. J Appl Physiol, 99(3):963-71.
-
(2005)
J Appl Physiol
, vol.99
, Issue.3
, pp. 963-971
-
-
Vanterpool, C.K.1
Pearce, W.J.2
-
124
-
-
0034853813
-
Ultrastructure evidence of necrotic neural cell death in familial Alzheimer's disease brains bearing presenilin-1 E280A.mutation
-
Velez-Pardo C, Arroyave ST, et al. 2001. Ultrastructure evidence of necrotic neural cell death in familial Alzheimer's disease brains bearing presenilin-1 E280A.mutation. J Alzheimers Dis, 3(4):409-415.
-
(2001)
J Alzheimers Dis
, vol.3
, Issue.4
, pp. 409-415
-
-
Velez-Pardo, C.1
Arroyave, S.T.2
-
125
-
-
0029670620
-
Calcium-induced calcium release in neurones
-
Verkhratsky A, Shmigol A. 1996. Calcium-induced calcium release in neurones. Cell Calcium, 19(1):1-14.
-
(1996)
Cell Calcium
, vol.19
, Issue.1
, pp. 1-14
-
-
Verkhratsky, A.1
Shmigol, A.2
-
126
-
-
36048943514
-
-
Verkhratsky AT, EC. 1998. Integrative Aspects of Calcium Signalling. A. T. Verkhratsky, E.C London, Plenium Press428
-
Verkhratsky AT, EC. 1998. Integrative Aspects of Calcium Signalling. A. T. Verkhratsky, E.C London, Plenium Press428
-
-
-
-
127
-
-
2542427690
-
Oligomers on the brain: The emerging role of soluble protein aggregates in neurodegeneration
-
Walsh DM, Selkoe DJ. 2004. Oligomers on the brain: the emerging role of soluble protein aggregates in neurodegeneration. Protein Pept Lett, 11(3):213-28.
-
(2004)
Protein Pept Lett
, vol.11
, Issue.3
, pp. 213-228
-
-
Walsh, D.M.1
Selkoe, D.J.2
-
128
-
-
33744952846
-
Wild-type presenilin 1 protects against Alzheimer disease mutation-induced amyloid pathology
-
Wang R, Wang B, et al. 2006. Wild-type presenilin 1 protects against Alzheimer disease mutation-induced amyloid pathology. J Biol Chem, 281(22):15330-6.
-
(2006)
J Biol Chem
, vol.281
, Issue.22
, pp. 15330-15336
-
-
Wang, R.1
Wang, B.2
-
129
-
-
0042508791
-
Neuropathologic changes in Alzheimer's disease
-
Wenk GL. 2003. Neuropathologic changes in Alzheimer's disease. J Clin Psychiatry, 64 Suppl 9:7-10.
-
(2003)
J Clin Psychiatry
, vol.64
, Issue.SUPPL. 9
, pp. 7-10
-
-
Wenk, G.L.1
-
130
-
-
33645470003
-
Neuropathologic changes in Alzheimer's disease: Potential targets for treatment
-
quiz 23
-
Wenk GL. 2006. Neuropathologic changes in Alzheimer's disease: potential targets for treatment. J Clin Psychiatry, 67 Suppl 3:3-7; quiz 23.
-
(2006)
J Clin Psychiatry
, vol.67
, Issue.SUPPL. 3
, pp. 3-7
-
-
Wenk, G.L.1
-
131
-
-
0032529710
-
Survival of cultured neurons from amyloid precursor protein knock-out mice against Alzheimer's amyloid-beta toxicity and oxidative stress
-
White AR, Zheng H, et al. 1998. Survival of cultured neurons from amyloid precursor protein knock-out mice against Alzheimer's amyloid-beta toxicity and oxidative stress. J Neurosci, 18(16):6207-17.
-
(1998)
J Neurosci
, vol.18
, Issue.16
, pp. 6207-6217
-
-
White, A.R.1
Zheng, H.2
-
132
-
-
0024543836
-
Amyloid beta protein enhances the survival of hippocampal neurons in vitro
-
Whitson JS, Selkoe DJ, et al. 1989. Amyloid beta protein enhances the survival of hippocampal neurons in vitro. Science, 243(4897):1488-90.
-
(1989)
Science
, vol.243
, Issue.4897
, pp. 1488-1490
-
-
Whitson, J.S.1
Selkoe, D.J.2
-
133
-
-
0030952217
-
Intracellular generation and accumulation of amyloid beta-peptide terminating at amino acid 42
-
Wild-Bode C, Yamazaki T, et al. 1997. Intracellular generation and accumulation of amyloid beta-peptide terminating at amino acid 42. J Biol Chem, 272(26):16085-8.
-
(1997)
J Biol Chem
, vol.272
, Issue.26
, pp. 16085-16088
-
-
Wild-Bode, C.1
Yamazaki, T.2
-
134
-
-
0032800818
-
Intracellular APP processing and A beta production in Alzheimer disease
-
Wilson CA, Doms RW, et al. 1999. Intracellular APP processing and A beta production in Alzheimer disease. J Neuropathol Exp Neurol, 58(8):787-94.
-
(1999)
J Neuropathol Exp Neurol
, vol.58
, Issue.8
, pp. 787-794
-
-
Wilson, C.A.1
Doms, R.W.2
-
135
-
-
0036727463
-
Presenilins are not required for A beta 42 production in the early secretory pathway
-
Wilson CA, Doms RW, et al. 2002. Presenilins are not required for A beta 42 production in the early secretory pathway. Nat Neurosci, 5(9):849-55.
-
(2002)
Nat Neurosci
, vol.5
, Issue.9
, pp. 849-855
-
-
Wilson, C.A.1
Doms, R.W.2
-
136
-
-
0032983786
-
Memantine in severe dementia: Results of the 9M-Best Study (Benefit and efficacy in severely demented patients during treatment with memantine)
-
Winblad B, Poritis N. 1999. Memantine in severe dementia: results of the 9M-Best Study (Benefit and efficacy in severely demented patients during treatment with memantine). Int J Geriatr Psychiatry, 14(2):135-46.
-
(1999)
Int J Geriatr Psychiatry
, vol.14
, Issue.2
, pp. 135-146
-
-
Winblad, B.1
Poritis, N.2
-
137
-
-
7244236841
-
A modified beta-amyloid hypothesis: Intraneuronal accumulation of the beta-amyloid peptie - the first step of a fatal cascade
-
Wirths O, Multhaup G, et al. 2004. A modified beta-amyloid hypothesis: intraneuronal accumulation of the beta-amyloid peptie - the first step of a fatal cascade. J Neurochem, 91(3):513-20.
-
(2004)
J Neurochem
, vol.91
, Issue.3
, pp. 513-520
-
-
Wirths, O.1
Multhaup, G.2
-
138
-
-
0036019155
-
Intraneuronal APP/A beta trafficking and plaque formation in beta-amyloid precursor protein and presenilin-1 transgenic mice
-
Wirths O, Multhaup G, et al. 2002. Intraneuronal APP/A beta trafficking and plaque formation in beta-amyloid precursor protein and presenilin-1 transgenic mice. Brain Pathol, 12(3):275-86.
-
(2002)
Brain Pathol
, vol.12
, Issue.3
, pp. 275-286
-
-
Wirths, O.1
Multhaup, G.2
-
139
-
-
0022297190
-
Neuritic plaques and cerebrovascular amyloid in Alzheimer disease are antigenically related
-
Wong CW, Quaranta V, et al. 1985. Neuritic plaques and cerebrovascular amyloid in Alzheimer disease are antigenically related. Proc Natl Acad Sci USA, 82(24):8729-32.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, Issue.24
, pp. 8729-8732
-
-
Wong, C.W.1
Quaranta, V.2
-
140
-
-
0036877135
-
Molecular physiology of the SERCA and SPCA pumps
-
Wuytack F, Raeymaekers L, et al. 2002. Molecular physiology of the SERCA and SPCA pumps. Cell Calcium, 32(5-6):279-305.
-
(2002)
Cell Calcium
, vol.32
, Issue.5-6
, pp. 279-305
-
-
Wuytack, F.1
Raeymaekers, L.2
-
141
-
-
0030239827
-
alpha-calcium-calmodulin-dependent kinase II is associated with paired helical filaments of Alzheimer's disease
-
Xiao J, Perry G, et al. 1996. alpha-calcium-calmodulin-dependent kinase II is associated with paired helical filaments of Alzheimer's disease. J Neuropathol Exp Neurol, 55(9):954-63.
-
(1996)
J Neuropathol Exp Neurol
, vol.55
, Issue.9
, pp. 954-963
-
-
Xiao, J.1
Perry, G.2
-
142
-
-
0030963605
-
Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation
-
Xu H, Sweeney D, et al. 1997. Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation. Proc Natl Acad Sci U S A, 94(8):3748-52.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, Issue.8
, pp. 3748-3752
-
-
Xu, H.1
Sweeney, D.2
-
143
-
-
0024990330
-
Neurotrophic and neurotoxic effects of amyloid beta protein: Reversal by tachykinin neuropeptides
-
Yankner BA, Duffy LK, et al. 1990. Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides. Science, 250(4978):279-82.
-
(1990)
Science
, vol.250
, Issue.4978
, pp. 279-282
-
-
Yankner, B.A.1
Duffy, L.K.2
-
144
-
-
0022444350
-
The ninth component of complement and the pore-forming protein (perforin 1) from cytotoxic T cells: Structural, immunological, and functional similarities
-
Young JD, Cohn ZA, et al. 1986. The ninth component of complement and the pore-forming protein (perforin 1) from cytotoxic T cells: structural, immunological, and functional similarities. Science, 233(4760):184-90.
-
(1986)
Science
, vol.233
, Issue.4760
, pp. 184-190
-
-
Young, J.D.1
Cohn, Z.A.2
-
145
-
-
0032105394
-
The role of A Beta 42 in Alzheimer's disease
-
Younkin SG. 1998. The role of A Beta 42 in Alzheimer's disease. J Physiol (Paris), 92:289-292.
-
(1998)
J Physiol (Paris)
, vol.92
, pp. 289-292
-
-
Younkin, S.G.1
-
146
-
-
0033947688
-
From form to function: Calcium compartmentalization in dendritic spines
-
Yuste R, Majewska A, et al. 2000. From form to function: calcium compartmentalization in dendritic spines. Nat Neurosci, 3(7):653-9.
-
(2000)
Nat Neurosci
, vol.3
, Issue.7
, pp. 653-659
-
-
Yuste, R.1
Majewska, A.2
-
147
-
-
0028988801
-
beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity
-
Zheng H, Jiang M, et al. 1995. beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity. Cell, 81(4):525-31.
-
(1995)
Cell
, vol.81
, Issue.4
, pp. 525-531
-
-
Zheng, H.1
Jiang, M.2
|