Presenilin-1 P264L knock-in mutation: Differential effects on Aβ production, amyloid deposition, and neuronal vulnerability

Journal of Neuroscience

Volumn 20, Issue 23, 2000, Pages 8717-8726

  Siman, R ^a   Reaume, A G ^a   Savage, M J ^a   Trusko, S ^a   Lin, Y G ^a   Scott, R W ^a   Flood, D G ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Amyloid; Amyloid precursor protein; A ; Familial Alzheimer's Disease; Gene targeting; Neuronal apoptosis; Plaque; Plaque, neuronal necrosis; Presenilin

Indexed keywords

PRESENILIN 1;

ALZHEIMER DISEASE; ANIMAL CELL; APOPTOSIS; ARTICLE; GENE MUTATION; GENE TARGETING; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN PROCESSING;

EID: 0034551780     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-23-08717.2000     Document Type: Article

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