메뉴 건너뛰기




Volumn 24, Issue 27, 2004, Pages 6049-6056

β-amyloid-mediated inhibition of NMDA receptor-dependent long-term potentiation induction involves activation of microglia and stimulation of inducible nitric oxide synthase and superoxide

Author keywords

Amyloid protein; Caspases; Dentate gyrus; Inducible nitric oxide; LTP; Microglia; Superoxide

Indexed keywords

AMINOGUANIDINE; AMYLOID BETA PROTEIN; CATALASE; INDUCIBLE NITRIC OXIDE SYNTHASE; MINOCYCLINE; N [3 (AMINOMETHYL)BENZYL]ACETAMIDINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NITRIC OXIDE; PEROXYNITRITE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE INHIBITOR; SCAVENGER; SUPEROXIDE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

EID: 3042798841     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0233-04.2004     Document Type: Article
Times cited : (187)

References (55)
  • 1
    • 0034678024 scopus 로고    scopus 로고
    • β-amyloid stimulation of inducible nitric oxide synthase in astrocytes is IL-1β- and TNF-α-dependent
    • Akama KT, Van Eldik LJV (2000) β-Amyloid stimulation of inducible nitric oxide synthase in astrocytes is IL-1β- and TNF-α-dependent. J Biol Chem 275:7918-7924.
    • (2000) J Biol Chem , vol.275 , pp. 7918-7924
    • Akama, K.T.1    Van Eldik, L.J.V.2
  • 2
    • 0032510692 scopus 로고    scopus 로고
    • Amyloid β-peptide stimulates nitric oxide production in astrocytes through an NF-κB-dependent mechanism
    • Akama KT, Albanese C, Pestell RG, Van Eldik LJ (1998) Amyloid β-peptide stimulates nitric oxide production in astrocytes through an NF-κB-dependent mechanism. Proc Natl Acad Sci USA 95:5795-5800.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 5795-5800
    • Akama, K.T.1    Albanese, C.2    Pestell, R.G.3    Van Eldik, L.J.4
  • 4
    • 0037387147 scopus 로고    scopus 로고
    • A cell surface receptor complex for fibrillar β-amyloid mediates microglial activation
    • Bamberger ME, Harris ME, McDonald DR, Husemann J, Landreth GE (2003) A cell surface receptor complex for fibrillar β-amyloid mediates microglial activation. J Neurosci 23:2665-2674.
    • (2003) J Neurosci , vol.23 , pp. 2665-2674
    • Bamberger, M.E.1    Harris, M.E.2    McDonald, D.R.3    Husemann, J.4    Landreth, G.E.5
  • 5
    • 0032983334 scopus 로고    scopus 로고
    • Beta-amyloid activates the O-2 forming NADPH oxidase in microglia, monocytes, and neutrophils. A possible inflammatory mechanism of neuronal damage in Alzheimer's disease
    • Bianca VD, Dusi S, Bianchini E, Dal Pra I, Rossi F (1999) Beta-amyloid activates the O-2 forming NADPH oxidase in microglia, monocytes, and neutrophils. A possible inflammatory mechanism of neuronal damage in Alzheimer's disease. J Biol Chem 274:15493-15499.
    • (1999) J Biol Chem , vol.274 , pp. 15493-15499
    • Bianca, V.D.1    Dusi, S.2    Bianchini, E.3    Dal Pra, I.4    Rossi, F.5
  • 6
    • 0029926519 scopus 로고    scopus 로고
    • Two forms of long-term potentiation in area CA1 activate different signal transduction cascades
    • Cavus I, Teyler T (1996) Two forms of long-term potentiation in area CA1 activate different signal transduction cascades. J Neurophysiol 76:3038-3047.
    • (1996) J Neurophysiol , vol.76 , pp. 3038-3047
    • Cavus, I.1    Teyler, T.2
  • 7
    • 0034069795 scopus 로고    scopus 로고
    • Impairments of hippocampal long-term potentiation by Alzheimer β-peptide
    • Chen Q, Kagan BL, Hirajura Y, Xie C (2000) Impairments of hippocampal long-term potentiation by Alzheimer β-peptide. J Neurosci Res 60:65-72.
    • (2000) J Neurosci Res , vol.60 , pp. 65-72
    • Chen, Q.1    Kagan, B.L.2    Hirajura, Y.3    Xie, C.4
  • 8
    • 0032947058 scopus 로고    scopus 로고
    • MAP kinase pathways
    • Cobb MH (1999) MAP kinase pathways. Prog Biophys Mol Biol 71:479-500.
    • (1999) Prog Biophys Mol Biol , vol.71 , pp. 479-500
    • Cobb, M.H.1
  • 9
    • 0034651101 scopus 로고    scopus 로고
    • Inflammatory mechanisms in Alzheimer's disease: Inhibition of β-amyloid-stimulated proinflammatory responses and neurotoxicity by PPAR-γagonist
    • Combs CK, Johnson DE, Karlo JC, Cannady SB, Landreth GE (2000) Inflammatory mechanisms in Alzheimer's disease: inhibition of β-amyloid-stimulated proinflammatory responses and neurotoxicity by PPAR-γagonist. J Neurosci 20:558-567.
    • (2000) J Neurosci , vol.20 , pp. 558-567
    • Combs, C.K.1    Johnson, D.E.2    Karlo, J.C.3    Cannady, S.B.4    Landreth, G.E.5
  • 10
    • 0029912056 scopus 로고    scopus 로고
    • Mechanisms of neuronal death in Alzheimer's disease
    • Cotman CW, Su JH (1996) Mechanisms of neuronal death in Alzheimer's disease. Brain Pathol 4:493-506.
    • (1996) Brain Pathol , vol.4 , pp. 493-506
    • Cotman, C.W.1    Su, J.H.2
  • 11
    • 0030809128 scopus 로고    scopus 로고
    • Block of LTP in rat hippocampus in vivo by β-amyloid precursor protein fragments
    • Cullen WK, Suh Y-H, Anwyl R, Rowan MJ (1997) Block of LTP in rat hippocampus in vivo by β-amyloid precursor protein fragments. NeuroReport 8:3213-3217.
    • (1997) NeuroReport , vol.8 , pp. 3213-3217
    • Cullen, W.K.1    Suh, Y.-H.2    Anwyl, R.3    Rowan, M.J.4
  • 12
    • 0030712362 scopus 로고    scopus 로고
    • Blockade of p38 mitogen-activated protein kinase pathway inhibits inducible nitric-oxide synthase expression in mouse astrocytes
    • Da Silva J, Pierrat B, Mary JL, LessIauer W (1997) Blockade of p38 mitogen-activated protein kinase pathway inhibits inducible nitric-oxide synthase expression in mouse astrocytes. J Biol Chem 272:28373-28380.
    • (1997) J Biol Chem , vol.272 , pp. 28373-28380
    • Da Silva, J.1    Pierrat, B.2    Mary, J.L.3    LessIauer, W.4
  • 16
    • 0031040613 scopus 로고    scopus 로고
    • 1400W is a slow, tight-binding, and highly selective inhibitor of inducible nitric-oxide synthase in vitro and in vivo
    • Garvey EP, Oplinger JA, Furfine ES, Kiff RJ, Laszlo F, Whittle BJ, Knowles RG (1997) 1400W is a slow, tight-binding, and highly selective inhibitor of inducible nitric-oxide synthase in vitro and in vivo. J Biol Chem 272: 4959-4963.
    • (1997) J Biol Chem , vol.272 , pp. 4959-4963
    • Garvey, E.P.1    Oplinger, J.A.2    Furfine, E.S.3    Kiff, R.J.4    Laszlo, F.5    Whittle, B.J.6    Knowles, R.G.7
  • 18
    • 0031893085 scopus 로고    scopus 로고
    • Evidence for postsynaptic induction and expression of NMDA receptor independent LTP
    • Grover L (1998) Evidence for postsynaptic induction and expression of NMDA receptor independent LTP. J Neurophysiol 79:1167-1182.
    • (1998) J Neurophysiol , vol.79 , pp. 1167-1182
    • Grover, L.1
  • 19
    • 0025089008 scopus 로고
    • Two components of long-term potentiation induced by different patterns of afferent activation
    • Grover L, Teyler TJ (1990) Two components of long-term potentiation induced by different patterns of afferent activation. Nature 347:477-479.
    • (1990) Nature , vol.347 , pp. 477-479
    • Grover, L.1    Teyler, T.J.2
  • 21
    • 0035654078 scopus 로고    scopus 로고
    • Dendritic spines: Structure, dynamics, and regulation
    • Hering H, Sheng M (2001) Dendritic spines: structure, dynamics, and regulation. Nat Rev Neurosci 2:880-888.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 880-888
    • Hering, H.1    Sheng, M.2
  • 22
    • 0032754051 scopus 로고    scopus 로고
    • Impairment of long-term potentiation in hippocampal slices of β-amyloid-infused rats
    • Itoh A, Akaike T, Sokabe M, Nitta A, Nabeshima T (1999) Impairment of long-term potentiation in hippocampal slices of β-amyloid-infused rats. Eur J Pharmacol 3:167-175.
    • (1999) Eur J Pharmacol , vol.3 , pp. 167-175
    • Itoh, A.1    Akaike, T.2    Sokabe, M.3    Nitta, A.4    Nabeshima, T.5
  • 23
    • 0344393017 scopus 로고    scopus 로고
    • Paradoxical actions of hydrogen peroxide on long-term potentiation in transgenic superoxide dismutase-1 mice
    • Kamsler A, Segal M (2003) Paradoxical actions of hydrogen peroxide on long-term potentiation in transgenic superoxide dismutase-1 mice. J Neurosci 23:10359-10367.
    • (2003) J Neurosci , vol.23 , pp. 10359-10367
    • Kamsler, A.1    Segal, M.2
  • 24
    • 0032548843 scopus 로고    scopus 로고
    • A role for superoxide in protein kinase C activation and induction of long-term potentiation
    • Klann E, Robertson ED, Knapp LT, Sweatt JD (1998) A role for superoxide in protein kinase C activation and induction of long-term potentiation. J Biol Chem 273:4516-4522.
    • (1998) J Biol Chem , vol.273 , pp. 4516-4522
    • Klann, E.1    Robertson, E.D.2    Knapp, L.T.3    Sweatt, J.D.4
  • 26
    • 0028843127 scopus 로고
    • Aminoguanidine inhibits both constitutive and inducible nitric oxide synthase isoforms in rat intestinal microvasculature in vivo
    • Laszlo F, Evans SM, Whittle BJ (1995) Aminoguanidine inhibits both constitutive and inducible nitric oxide synthase isoforms in rat intestinal microvasculature in vivo. Eur J Pharmacol 272:169-175.
    • (1995) Eur J Pharmacol , vol.272 , pp. 169-175
    • Laszlo, F.1    Evans, S.M.2    Whittle, B.J.3
  • 27
    • 1242274383 scopus 로고    scopus 로고
    • Tumor necrosis factor death receptor signaling cascade is required for amyloid-β protein-induced neuron death
    • Li R, Yang L, Lindholm K, Konishi Y, Yue X, Hampel H, Zhang D, Shen Y (2004) Tumor necrosis factor death receptor signaling cascade is required for amyloid-β protein-induced neuron death. J Neurosci 24:1760-1771.
    • (2004) J Neurosci , vol.24 , pp. 1760-1771
    • Li, R.1    Yang, L.2    Lindholm, K.3    Konishi, Y.4    Yue, X.5    Hampel, H.6    Zhang, D.7    Shen, Y.8
  • 28
    • 0031980291 scopus 로고    scopus 로고
    • Peroxynitrite induces apoptosis of HL-60 cells by activation of a caspase-3 family protease
    • Lin KT, Xue JY, Lin MC, Spokas EG, Sun FF, Wong PY (1998) Peroxynitrite induces apoptosis of HL-60 cells by activation of a caspase-3 family protease. Am J Physiol 274:C855-C860.
    • (1998) Am J Physiol , vol.274
    • Lin, K.T.1    Xue, J.Y.2    Lin, M.C.3    Spokas, E.G.4    Sun, F.F.5    Wong, P.Y.6
  • 30
    • 0036513485 scopus 로고    scopus 로고
    • The molecular basts of CaMKII function in synaptic and behavioural memory
    • Lisman J, Schulman H, Cline H (2002) The molecular basts of CaMKII function in synaptic and behavioural memory. Nat Rev Neurosci 3:175-190.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 175-190
    • Lisman, J.1    Schulman, H.2    Cline, H.3
  • 31
    • 0031900411 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory use and Alzheimer-type pathology in aging
    • MacKenzie IR, Munoz DG (1998) Nonsteroidal anti-inflammatory use and Alzheimer-type pathology in aging. Neurology 50:986-990.
    • (1998) Neurology , vol.50 , pp. 986-990
    • MacKenzie, I.R.1    Munoz, D.G.2
  • 32
    • 0036433323 scopus 로고    scopus 로고
    • New life in an old idea: The synaptic plasticity and memory hypothesis revisited
    • Martin SJ, Morris RG (2002) New life in an old idea: the synaptic plasticity and memory hypothesis revisited. Hippocampus 12:609-636.
    • (2002) Hippocampus , vol.12 , pp. 609-636
    • Martin, S.J.1    Morris, R.G.2
  • 33
    • 0030961544 scopus 로고    scopus 로고
    • Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia
    • McDonald DR, Brunden KR, Landreth GE (1997) Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia. J Neurosci 17:2284-2288.
    • (1997) J Neurosci , vol.17 , pp. 2284-2288
    • McDonald, D.R.1    Brunden, K.R.2    Landreth, G.E.3
  • 35
    • 0029610011 scopus 로고
    • The inflammatory response system of the brain: Implications for therapy of Alzheimer and other neurodegenerative diseases
    • McGeer PL, McGeer EG (1995) The inflammatory response system of the brain: implications for therapy of Alzheimer and other neurodegenerative diseases. Brain Res Rev 21:195-218.
    • (1995) Brain Res Rev , vol.21 , pp. 195-218
    • McGeer, P.L.1    McGeer, E.G.2
  • 36
    • 0031985513 scopus 로고    scopus 로고
    • Microglia as effector cells in brain damage and repair: Focus on prostanoids and nitric oxide
    • Minghetti L, Levi G (1998) Microglia as effector cells in brain damage and repair: focus on prostanoids and nitric oxide. Prog Neurobiol 54:99-125.
    • (1998) Prog Neurobiol , vol.54 , pp. 99-125
    • Minghetti, L.1    Levi, G.2
  • 37
    • 0036845314 scopus 로고    scopus 로고
    • Microglia enhance β-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species
    • Qin L, Liu Y, Cooper C, Liu B, Wilson B, Hong J-S (2002) Microglia enhance β-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species. J Neurochem 83:973-983.
    • (2002) J Neurochem , vol.83 , pp. 973-983
    • Qin, L.1    Liu, Y.2    Cooper, C.3    Liu, B.4    Wilson, B.5    Hong, J.-S.6
  • 38
    • 0037432559 scopus 로고    scopus 로고
    • NMDA receptor regulation by amyloid-β does not account for its inhibition of LTP in rat hippocampus
    • Raymond CR, Ireland DR, Abraham WC (2003) NMDA receptor regulation by amyloid-β does not account for its inhibition of LTP in rat hippocampus. Brain Res 968:263-272.
    • (2003) Brain Res , vol.968 , pp. 263-272
    • Raymond, C.R.1    Ireland, D.R.2    Abraham, W.C.3
  • 39
    • 0034998271 scopus 로고    scopus 로고
    • Minocycline reduces traumatic brain injury-mediated caspase-1 activation, tissue damage, and neurological dysfunction
    • Sanchez Mejia RO, Ona VO, Li M, Friedlander RM (2001) Minocycline reduces traumatic brain injury-mediated caspase-1 activation, tissue damage, and neurological dysfunction. Neurosurgery 48:1393-1401.
    • (2001) Neurosurgery , vol.48 , pp. 1393-1401
    • Sanchez Mejia, R.O.1    Ona, V.O.2    Li, M.3    Friedlander, R.M.4
  • 40
    • 0037174618 scopus 로고    scopus 로고
    • Alzheimer's disease is a synaptic failure
    • Selkoe DJ (2002) Alzheimer's disease is a synaptic failure. Science 298:789-791.
    • (2002) Science , vol.298 , pp. 789-791
    • Selkoe, D.J.1
  • 41
    • 0035433962 scopus 로고    scopus 로고
    • Alzheimer's disease and Aβ toxicity: From top to bottom
    • Small DH, Mok SS, Bornstein JC (2001) Alzheimer's disease and Aβ toxicity: from top to bottom. Nat Rev Neurosci 8:595-598.
    • (2001) Nat Rev Neurosci , vol.8 , pp. 595-598
    • Small, D.H.1    Mok, S.S.2    Bornstein, J.C.3
  • 43
    • 0035425615 scopus 로고    scopus 로고
    • Generation of aggregated β-amyloid in the rat hippocampus impairs synaptic transmission and plasticity and causes memory deficits
    • Stephan A, Laroche S, Davis S (2001) Generation of aggregated β-amyloid in the rat hippocampus impairs synaptic transmission and plasticity and causes memory deficits. J Neurosci 21:5703-5714.
    • (2001) J Neurosci , vol.21 , pp. 5703-5714
    • Stephan, A.1    Laroche, S.2    Davis, S.3
  • 45
    • 0035871840 scopus 로고    scopus 로고
    • Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia
    • Tikka T, Fiebich B, Goldsteins G, Keinanen R, Koistinaho J (2001) Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia. J Neurosci 21:2580-2588.
    • (2001) J Neurosci , vol.21 , pp. 2580-2588
    • Tikka, T.1    Fiebich, B.2    Goldsteins, G.3    Keinanen, R.4    Koistinaho, J.5
  • 46
    • 0033604506 scopus 로고    scopus 로고
    • LTP promotes formation of multiple spine synapses between a single axon terminal and a dendrite
    • Toni N, Buchs PA, Nikonenko I, Bron CR, Muller D (1999) (1999) LTP promotes formation of multiple spine synapses between a single axon terminal and a dendrite. Nature 402:421-425.
    • (1999) Nature , vol.402 , pp. 421-425
    • Toni, N.1    Buchs, P.A.2    Nikonenko, I.3    Bron, C.R.4    Muller, D.5
  • 47
    • 0036792096 scopus 로고    scopus 로고
    • Amyloid β-peptide inhibition of the PKA/CREB pathway and long-term potentiation: Reversibility by drugs that enhance cAMP signaling
    • Vitolo OV, Sant'Angelo A, Costanzo V, Battaglia F, Arancio O, Shelanski M (2002) Amyloid β-peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling. Proc Natl Acad Sci USA 99:13217-13221.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 13217-13221
    • Vitolo, O.V.1    Sant'Angelo, A.2    Costanzo, V.3    Battaglia, F.4    Arancio, O.5    Shelanski, M.6
  • 48
    • 0031127418 scopus 로고    scopus 로고
    • Nitric oxide synthase in reactive astrocytes adjacent to β-amyloid
    • Wallace MN, Geddes JG, Farquar DA, Masson MR (1997) Nitric oxide synthase in reactive astrocytes adjacent to β-amyloid. Exp Neurol 144:266-272.
    • (1997) Exp Neurol , vol.144 , pp. 266-272
    • Wallace, M.N.1    Geddes, J.G.2    Farquar, D.A.3    Masson, M.R.4
  • 49
    • 0037041426 scopus 로고    scopus 로고
    • Naturally secreted oligomers of the Alzheimer amyloid β-protein potently inhibit long-term potentiation in vivo
    • Walsh DM, Klyubuin I, Fadeeva J, Cullen WK, Anwyl R, Wolfe MS, Rowan MJ, Selkoe DJ (2002) Naturally secreted oligomers of the Alzheimer amyloid β-protein potently inhibit long-term potentiation in vivo. Nature 416:535-539.
    • (2002) Nature , vol.416 , pp. 535-539
    • Walsh, D.M.1    Klyubuin, I.2    Fadeeva, J.3    Cullen, W.K.4    Anwyl, R.5    Wolfe, M.S.6    Rowan, M.J.7    Selkoe, D.J.8
  • 51
    • 1842610852 scopus 로고    scopus 로고
    • Block of LTP by naturally secreted and synthetic amyloid β-peptide in hippocampal slices is mediated via activation of the kinases JNK, Cdk5, and p38 MAPK as well as mGluR5
    • Wang Q, Walsh DM, Rowan MJ, Selkoe DJ, Anwyl R (2004) Block of LTP by naturally secreted and synthetic amyloid β-peptide in hippocampal slices is mediated via activation of the kinases JNK, Cdk5, and p38 MAPK as well as mGluR5. J Neurosci 24:3370-3378.
    • (2004) J Neurosci , vol.24 , pp. 3370-3378
    • Wang, Q.1    Walsh, D.M.2    Rowan, M.J.3    Selkoe, D.J.4    Anwyl, R.5
  • 52
    • 1242351596 scopus 로고    scopus 로고
    • An NMDAR-independent LTP mediated by group II metabotropic glutamate receptors and p42/44 MAP kinase in the dentate gyrus in vitro
    • Wu J, Rowan MJ, Anwyl R (2004) An NMDAR-independent LTP mediated by group II metabotropic glutamate receptors and p42/44 MAP kinase in the dentate gyrus in vitro. Neuropharmacology 46:311-331.
    • (2004) Neuropharmacology , vol.46 , pp. 311-331
    • Wu, J.1    Rowan, M.J.2    Anwyl, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.