Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 13, 2006, Pages 5161-5166

  Jacobsen, J Steven ^a   Wu, Chi Cheng ^b   Redwine, Jeffrey M ^b   Comery, Thomas A ^a   Arias, Robert ^a   Bowlby, Mark ^a   Martone, Robert ^a   Morrison, John H ^b,c   Pangalos, Menelas M ^a   Reinhart, Peter H ^a   Bloom, Floyd E ^b,d  

^a PFIZER INC   (United States)

^b Neurome Inc   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

amyloid; Cognition

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42];

ALZHEIMER DISEASE; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BEHAVIOR DISORDER; COGNITIVE DEFECT; CONDITIONING; CONTROLLED STUDY; DEGENERATIVE DISEASE; DENDRITIC SPINE; DENTATE GYRUS; DISEASE COURSE; ENTORHINAL CORTEX; FEAR; LONG TERM POTENTIATION; MALE; MEMORY DISORDER; MICROGLIA; MOUSE; NERVE DEGENERATION; NONHUMAN; PERFORANT NERVE TRACT; PRIORITY JOURNAL; SENILE PLAQUE; SYNAPTIC TRANSMISSION; TRANSGENIC MOUSE;

AGING; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; DISEASE MODELS, ANIMAL; FEAR; MEMORY; MICE; MICE, TRANSGENIC; ORGAN SIZE; SPINE; SYNAPSES; SYNAPTOPHYSIN; TIME FACTORS;

ANIMALIA; MUS MUSCULUS;

EID: 33645520634     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0600948103     Document Type: Article

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