Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 12, 1999, Pages 6959-6963

  Song, Weihong ^a   Nadeau, Philip ^a   Yuan, Menglan ^a   Yang, Xudong ^b   Shen, Jie ^b   Yankner, Bruce A ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE RECEPTOR; PRESENILIN 1;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE MUTATION; INTRACELLULAR TRANSPORT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ALZHEIMER DISEASE; ANIMALS; BIOLOGICAL TRANSPORT; CELL DIFFERENTIATION; CELL LINE; MEMBRANE PROTEINS; MICE; MORPHOGENESIS; MUTATION; PRESENILIN-1; RECEPTOR, NOTCH1; RECEPTORS, CELL SURFACE; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS;

ANIMALIA; CAENORHABDITIS ELEGANS;

EID: 0033536072     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.12.6959     Document Type: Article

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