Synaptic transmission and synchronous activity is disrupted in hippocampal slices taken from aged TAS10 mice

Hippocampus

Volumn 15, Issue 1, 2005, Pages 110-117

  Brown, Jon T ^a,b   Richardson, Jill C ^a   Collingridge, Graham L ^b   Randall, Andrew D ^a   Davies, Ceri H ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

4 aminopyridine; Alzheimer's disease; Electrophysiology; Glutamate; Transgenic mice

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 4 AMINOBUTYRIC ACID; 4 AMINOPYRIMIDINE; 6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; AMYLOID PRECURSOR PROTEIN; BICUCULLINE METHIODIDE; GLUTAMIC ACID; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

AGED; AGING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CELL SYNCHRONIZATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DENTATE GYRUS; FREQUENCY ANALYSIS; GABAERGIC TRANSMISSION; GENE OVEREXPRESSION; HIPPOCAMPUS; INFORMATION PROCESSING; LONG TERM POTENTIATION; MOUSE; MUTATIONAL ANALYSIS; NERVE CELL MEMBRANE POTENTIAL; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; SYNAPTIC TRANSMISSION; THETA RHYTHM; WILD TYPE;

4-AMINOPYRIDINE; ACTION POTENTIALS; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CORTICAL SYNCHRONIZATION; DISEASE MODELS, ANIMAL; ELECTRIC STIMULATION; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; HIPPOCAMPUS; LONG-TERM POTENTIATION; MICE; MICE, TRANSGENIC; MUTATION; NERVE NET; NEURAL INHIBITION; NEURAL PATHWAYS; ORGAN CULTURE TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; PRESYNAPTIC TERMINALS; QUINOXALINES; SYNAPTIC TRANSMISSION;

EID: 14844334934     PISSN: 10509631     EISSN: None     Source Type: Journal    
DOI: 10.1002/hipo.20036     Document Type: Article

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