-
1
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
-
McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984;34:939-944.
-
(1984)
Neurology
, vol.34
, pp. 939-944
-
-
McKhann, G.1
Drachman, D.2
Folstein, M.3
-
2
-
-
0036303818
-
Genetically engineered mouse models of neurodegenerative diseases
-
Wong PC, Cai H, Borchelt DR, Price DL. Genetically engineered mouse models of neurodegenerative diseases. Nat Neurosci 2002;5:633-639.
-
(2002)
Nat Neurosci
, vol.5
, pp. 633-639
-
-
Wong, P.C.1
Cai, H.2
Borchelt, D.R.3
Price, D.L.4
-
3
-
-
0029742199
-
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
-
Hsiao K, Chapman P, Nilsen S, et al. Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 1996;274:99-102.
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
-
4
-
-
0030612033
-
APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1
-
Irizarry MC, McNamara M, Fedorchak K, et al. APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1. J Neuropathol Exp Neurol 1997;56:965-973.
-
(1997)
J Neuropathol Exp Neurol
, vol.56
, pp. 965-973
-
-
Irizarry, M.C.1
McNamara, M.2
Fedorchak, K.3
-
5
-
-
0031974406
-
Microglial response to amyloid plaques in APPsw transgenic mice
-
Frautschy SA, Yang F, Irrizarry M, et al. Microglial response to amyloid plaques in APPsw transgenic mice. Am J Pathol 1998;152:307-317.
-
(1998)
Am J Pathol
, vol.152
, pp. 307-317
-
-
Frautschy, S.A.1
Yang, F.2
Irrizarry, M.3
-
6
-
-
0033360356
-
Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice
-
Chapman PF, White GL, Jones MW, et al. Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice. Nat Neurosci 1999;2:271-276.
-
(1999)
Nat Neurosci
, vol.2
, pp. 271-276
-
-
Chapman, P.F.1
White, G.L.2
Jones, M.W.3
-
7
-
-
0031914718
-
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
-
Holcomb L, Gordon MN, McGowan E, et al. Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes. Nat Med 1998;4:97-100.
-
(1998)
Nat Med
, vol.4
, pp. 97-100
-
-
Holcomb, L.1
Gordon, M.N.2
McGowan, E.3
-
8
-
-
0032756213
-
Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: Lack of association with amyloid deposits
-
Holcomb LA, Gordon MN, Jantzen P, et al. Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits. Behav Genet 1999;29:177-185.
-
(1999)
Behav Genet
, vol.29
, pp. 177-185
-
-
Holcomb, L.A.1
Gordon, M.N.2
Jantzen, P.3
-
9
-
-
0033199822
-
Progressive and gender-dependent cognitive impairment in the APP(SW) transgenic mouse model for Alzheimer's disease
-
King DL, Arendash GW, Crawford F, et al. Progressive and gender-dependent cognitive impairment in the APP(SW) transgenic mouse model for Alzheimer's disease. Behav Brain Res 1999;103:145-162.
-
(1999)
Behav Brain Res
, vol.103
, pp. 145-162
-
-
King, D.L.1
Arendash, G.W.2
Crawford, F.3
-
10
-
-
0032886415
-
Amyloid phenotype characterization of transgenic mice overexpressing both mutant amyloid precursor protein and mutant presenilin 1 transgenes
-
McGowan E, Sanders S, Iwatsubo T, et al. Amyloid phenotype characterization of transgenic mice overexpressing both mutant amyloid precursor protein and mutant presenilin 1 transgenes. Neurobiol Dis 1999;6:231-244.
-
(1999)
Neurobiol Dis
, vol.6
, pp. 231-244
-
-
McGowan, E.1
Sanders, S.2
Iwatsubo, T.3
-
11
-
-
0028898888
-
Mechanisms of synaptic dysfunction in Alzheimer's disease
-
Masliah E. Mechanisms of synaptic dysfunction in Alzheimer's disease. Histol Histopathol 1995;10:509-519.
-
(1995)
Histol Histopathol
, vol.10
, pp. 509-519
-
-
Masliah, E.1
-
12
-
-
0027476024
-
A synaptic model of memory: Long-term potentiation in the hippocampus
-
Bliss TV, Collingridge GL. A synaptic model of memory: long-term potentiation in the hippocampus. Nature 1993;361:31-39.
-
(1993)
Nature
, vol.361
, pp. 31-39
-
-
Bliss, T.V.1
Collingridge, G.L.2
-
13
-
-
0035399822
-
Age-related impairment of synaptic transmission but normal long-term potentiation in transgenic mice that overexpress the human APP695SWE mutant form of amyloid precursor protein
-
Fitzjohn SM, Morton RA, Kuenzi F, et al. Age-related impairment of synaptic transmission but normal long-term potentiation in transgenic mice that overexpress the human APP695SWE mutant form of amyloid precursor protein. J Neurosci 2001;21:4691-4698.
-
(2001)
J Neurosci
, vol.21
, pp. 4691-4698
-
-
Fitzjohn, S.M.1
Morton, R.A.2
Kuenzi, F.3
-
14
-
-
13044287361
-
Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models
-
Hsia AY, Masliah E, McConlogue L, et al. Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models. Proc Natl Acad Sci USA 1999;96:3228-3233.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 3228-3233
-
-
Hsia, A.Y.1
Masliah, E.2
McConlogue, L.3
-
15
-
-
0033523480
-
Alterations in synaptic transmission and long-term potentiation in hippocampal slices from young and aged PDAPP mice
-
Larson J, Lynch G, Games D, Seubert P. Alterations in synaptic transmission and long-term potentiation in hippocampal slices from young and aged PDAPP mice. Brain Res 1999;840:23-35.
-
(1999)
Brain Res
, vol.840
, pp. 23-35
-
-
Larson, J.1
Lynch, G.2
Games, D.3
Seubert, P.4
-
16
-
-
0033525520
-
Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain
-
Moechars D, Dewachter I, Lorent K, et al. Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain. J Biol Chem 1999;274:6483-6492.
-
(1999)
J Biol Chem
, vol.274
, pp. 6483-6492
-
-
Moechars, D.1
Dewachter, I.2
Lorent, K.3
-
17
-
-
0030978998
-
Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein
-
Nalbantoglu J, Tirado-Santiago G, Lahsaini A, et al. Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein. Nature 1997;387:500-505.
-
(1997)
Nature
, vol.387
, pp. 500-505
-
-
Nalbantoglu, J.1
Tirado-Santiago, G.2
Lahsaini, A.3
-
18
-
-
0037004511
-
Long-term potentiation is increased in the CA1 area of the hippocampus of APP(swe/ind) CRND8 mice
-
Jolas T, Zhang XS, Zhang Q, et al. Long-term potentiation is increased in the CA1 area of the hippocampus of APP(swe/ind) CRND8 mice. Neurobiol Dis 2002;11:394-409.
-
(2002)
Neurobiol Dis
, vol.11
, pp. 394-409
-
-
Jolas, T.1
Zhang, X.S.2
Zhang, Q.3
-
19
-
-
0030809128
-
Block of LTP in rat hippocampus in vivo by beta-amyloid precursor protein fragments
-
Cullen WK, Suh YH, Anwyl R, Rowan MJ. Block of LTP in rat hippocampus in vivo by beta-amyloid precursor protein fragments. Neuroreport 1997;8:3213-3217.
-
(1997)
Neuroreport
, vol.8
, pp. 3213-3217
-
-
Cullen, W.K.1
Suh, Y.H.2
Anwyl, R.3
Rowan, M.J.4
-
20
-
-
0032754051
-
Impairments of long-term potentiation in hippocampal slices of beta-amyloid-infused rats
-
Itoh A, Akaike T, Sokabe M, et al. Impairments of long-term potentiation in hippocampal slices of beta-amyloid-infused rats. Eur J Pharmacol 1999;382:167-175.
-
(1999)
Eur J Pharmacol
, vol.382
, pp. 167-175
-
-
Itoh, A.1
Akaike, T.2
Sokabe, M.3
-
21
-
-
0037041426
-
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
-
Walsh DM, Klyubin I, Fadeeva JV, et al. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature 2002;416:535-539.
-
(2002)
Nature
, vol.416
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
-
22
-
-
0036792096
-
Amyloid beta-peptide inhibition of the PKA/CREB pathway and long-term potentiation: Reversibility by drugs that enhance cAMP signaling
-
Vitolo OV, Sant'Angelo A, Costanzo V, et al. Amyloid beta-peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling. Proc Natl Acad Sci USA 2002;99:13217-13221.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13217-13221
-
-
Vitolo, O.V.1
Sant'Angelo, A.2
Costanzo, V.3
-
23
-
-
0037955990
-
Usefulness of behavioral and electrophysiological studies in transgenic models of Alzheimer's disease
-
Sant'Angelo A, Trinchese F, Arancio O. Usefulness of behavioral and electrophysiological studies in transgenic models of Alzheimer's disease. Neurochem Res 2003;28:1009-1015.
-
(2003)
Neurochem Res
, vol.28
, pp. 1009-1015
-
-
Sant'Angelo, A.1
Trinchese, F.2
Arancio, O.3
-
24
-
-
16044366039
-
Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1
-
Duff K, Eckman C, Zehr C, et al. Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1. Nature 1996;383:710-713.
-
(1996)
Nature
, vol.383
, pp. 710-713
-
-
Duff, K.1
Eckman, C.2
Zehr, C.3
-
25
-
-
0042466644
-
Receptor protein tyrosine phosphatase alpha is essential for hippocampal neuronal migration and long-term potentiation
-
Petrone A, Battaglia F, Wang C, et al. Receptor protein tyrosine phosphatase alpha is essential for hippocampal neuronal migration and long-term potentiation. EMBO J 2003;22:4121-4131.
-
(2003)
EMBO J
, vol.22
, pp. 4121-4131
-
-
Petrone, A.1
Battaglia, F.2
Wang, C.3
-
26
-
-
0034044741
-
Strain-dependent differences in LTP and hippocampus-dependent memory in inbred mice
-
Nguyen PV, Abel T, Kandel ER, Bourtchouladze R. Strain-dependent differences in LTP and hippocampus-dependent memory in inbred mice. Learn Mem 2000;7:170-179.
-
(2000)
Learn Mem
, vol.7
, pp. 170-179
-
-
Nguyen, P.V.1
Abel, T.2
Kandel, E.R.3
Bourtchouladze, R.4
-
27
-
-
84984755327
-
A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
-
Morgan D, Diamond DM, Gottschall PE, et al. A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature 2000;408:982-985.
-
(2000)
Nature
, vol.408
, pp. 982-985
-
-
Morgan, D.1
Diamond, D.M.2
Gottschall, P.E.3
-
28
-
-
0019957779
-
Place navigation impaired in rats with hippocampal lesions
-
Morris RG, Garrud P, Rawlins JN, O'Keefe J. Place navigation impaired in rats with hippocampal lesions. Nature 1982;297:681-683.
-
(1982)
Nature
, vol.297
, pp. 681-683
-
-
Morris, R.G.1
Garrud, P.2
Rawlins, J.N.3
O'Keefe, J.4
-
29
-
-
0034704816
-
Apolipoprotein E and cognitive performance
-
Raber J, Wong D, Yu GQ, et al. Apolipoprotein E and cognitive performance. Nature 2000;404:352-354.
-
(2000)
Nature
, vol.404
, pp. 352-354
-
-
Raber, J.1
Wong, D.2
Yu, G.Q.3
-
30
-
-
0034700471
-
A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
-
Janus C, Pearson J, McLaurin J, et al. A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease. Nature 2000;408:979-982.
-
(2000)
Nature
, vol.408
, pp. 979-982
-
-
Janus, C.1
Pearson, J.2
McLaurin, J.3
-
31
-
-
0026023082
-
Detection of abnormal memory decline in mild cases of Alzheimer's disease using CERAD neuropsychological measures
-
Welsh K, Butters N, Hughes J, et al. Detection of abnormal memory decline in mild cases of Alzheimer's disease using CERAD neuropsychological measures. Arch Neurol 1991;48:278-281.
-
(1991)
Arch Neurol
, vol.48
, pp. 278-281
-
-
Welsh, K.1
Butters, N.2
Hughes, J.3
-
32
-
-
0026703853
-
Detection and staging of dementia in Alzheimer's disease. Use of the neuropsychological measures developed for the Consortium to Establish a Registry for Alzheimer's Disease
-
Welsh KA, Butters N, Hughes JP, et al. Detection and staging of dementia in Alzheimer's disease. Use of the neuropsychological measures developed for the Consortium to Establish a Registry for Alzheimer's Disease. Arch Neurol 1992;49:448-452.
-
(1992)
Arch Neurol
, vol.49
, pp. 448-452
-
-
Welsh, K.A.1
Butters, N.2
Hughes, J.P.3
-
33
-
-
0032737316
-
Exposing rats to a predator impairs spatial working memory in the radial arm water maze
-
Diamond DM, Park CR, Heman KL, Rose GM. Exposing rats to a predator impairs spatial working memory in the radial arm water maze. Hippocampus 1999;9:542-552.
-
(1999)
Hippocampus
, vol.9
, pp. 542-552
-
-
Diamond, D.M.1
Park, C.R.2
Heman, K.L.3
Rose, G.M.4
-
34
-
-
0036489445
-
The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease
-
Westerman MA, Cooper-Blacketer D, Mariash A, et al. The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease. J Neurosci 2002;22:1858-1867.
-
(2002)
J Neurosci
, vol.22
, pp. 1858-1867
-
-
Westerman, M.A.1
Cooper-Blacketer, D.2
Mariash, A.3
-
35
-
-
0035863055
-
Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease
-
Kawarabayashi T, Younkin LH, Saido TC, et al. Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease. J Neurosci 2001;21:372-381.
-
(2001)
J Neurosci
, vol.21
, pp. 372-381
-
-
Kawarabayashi, T.1
Younkin, L.H.2
Saido, T.C.3
-
36
-
-
0035830686
-
Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes
-
Arendash GW, King DL, Gordon MN, et al. Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes. Brain Res 2001;891:42-53.
-
(2001)
Brain Res
, vol.891
, pp. 42-53
-
-
Arendash, G.W.1
King, D.L.2
Gordon, M.N.3
-
37
-
-
0037454478
-
Abeta levels in serum, CSF and brain, and cognitive deficits in APP + PS1 transgenic mice
-
Liu L, Tapiola T, Herukka SK, et al. Abeta levels in serum, CSF and brain, and cognitive deficits in APP + PS1 transgenic mice. Neuroreport 2003;14:163-166.
-
(2003)
Neuroreport
, vol.14
, pp. 163-166
-
-
Liu, L.1
Tapiola, T.2
Herukka, S.K.3
-
38
-
-
0036235633
-
Hippocampal A beta 42 levels correlate with spatial memory deficit in APP and PS1 double transgenic mice
-
Puolivali J, Wang J, Heikkinen T, et al. Hippocampal A beta 42 levels correlate with spatial memory deficit in APP and PS1 double transgenic mice. Neurobiol Dis 2002;9:339-347.
-
(2002)
Neurobiol Dis
, vol.9
, pp. 339-347
-
-
Puolivali, J.1
Wang, J.2
Heikkinen, T.3
-
39
-
-
0042697305
-
Triple-transgenic model of Alzheimer's disease with plaques and tangles: Intracellular Abeta and synaptic dysfunction
-
Oddo S, Caccamo A, Shepherd JD, et al. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron 2003;39:409-421.
-
(2003)
Neuron
, vol.39
, pp. 409-421
-
-
Oddo, S.1
Caccamo, A.2
Shepherd, J.D.3
-
41
-
-
0033872024
-
Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss
-
Takeuchi A, Irizarry MC, Duff K, et al. Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss. Am J Pathol 2000;157:331-339.
-
(2000)
Am J Pathol
, vol.157
, pp. 331-339
-
-
Takeuchi, A.1
Irizarry, M.C.2
Duff, K.3
-
42
-
-
0032945724
-
Synaptic transmission and hippocampal long-term potentiation in transgenic mice expressing FAD-linked presenilin 1
-
Parent A, Linden DJ, Sisodia SS, Borchelt DR. Synaptic transmission and hippocampal long-term potentiation in transgenic mice expressing FAD-linked presenilin 1. Neurobiol Dis 1999;6:56-62.
-
(1999)
Neurobiol Dis
, vol.6
, pp. 56-62
-
-
Parent, A.1
Linden, D.J.2
Sisodia, S.S.3
Borchelt, D.R.4
-
43
-
-
0037151046
-
Accelerated plaque accumulation, associative learning deficits, and up-regulation of alpha 7 nicotinic receptor protein in transgenic mice co-expressing mutant human presenilin 1 and amyloid precursor proteins
-
Dineley KT, Xia X, Bui D, et al. Accelerated plaque accumulation, associative learning deficits, and up-regulation of alpha 7 nicotinic receptor protein in transgenic mice co-expressing mutant human presenilin 1 and amyloid precursor proteins. J Biol Chem 2002;277:22768-22780.
-
(2002)
J Biol Chem
, vol.277
, pp. 22768-22780
-
-
Dineley, K.T.1
Xia, X.2
Bui, D.3
-
44
-
-
0033501744
-
Behavioral disturbances in transgenic mice overexpressing the V717F beta-amyloid precursor protein
-
Dodart JC, Meziane H, Mathis C, et al. Behavioral disturbances in transgenic mice overexpressing the V717F beta-amyloid precursor protein. Behav Neurosci 1999;113:982-990.
-
(1999)
Behav Neurosci
, vol.113
, pp. 982-990
-
-
Dodart, J.C.1
Meziane, H.2
Mathis, C.3
-
45
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein
-
Games D, Adams D, Alessandrini R, et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein. Nature 1995;373:523-527.
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
-
46
-
-
0025150883
-
Presynaptic mechanism for long-term potentiation in the hippocampus
-
Bekkers JM, Stevens CF. Presynaptic mechanism for long-term potentiation in the hippocampus. Nature 1990;346:724-729.
-
(1990)
Nature
, vol.346
, pp. 724-729
-
-
Bekkers, J.M.1
Stevens, C.F.2
-
47
-
-
0030833055
-
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins
-
Borchelt DR, Ratovitski T, van Lare J, et al. Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron 1997;19:939-945.
-
(1997)
Neuron
, vol.19
, pp. 939-945
-
-
Borchelt, D.R.1
Ratovitski, T.2
Van Lare, J.3
-
48
-
-
0036240395
-
Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model
-
Dodart JC, Bales KR, Gannon KS, et al. Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model. Nat Neurosci 2002;5:452-457.
-
(2002)
Nat Neurosci
, vol.5
, pp. 452-457
-
-
Dodart, J.C.1
Bales, K.R.2
Gannon, K.S.3
-
49
-
-
0033622324
-
Intraneuronal Abeta42 accumulation in human brain
-
Gouras GK, Tsai J, Naslund J, et al. Intraneuronal Abeta42 accumulation in human brain. Am J Pathol 2000;156:15-20.
-
(2000)
Am J Pathol
, vol.156
, pp. 15-20
-
-
Gouras, G.K.1
Tsai, J.2
Naslund, J.3
-
50
-
-
0030793522
-
Neuronal cell death in Alzheimer's disease correlates with apoE uptake and intracellular Abeta stabilization
-
LaFerla FM, Troncoso JC, Strickland DK, et al. Neuronal cell death in Alzheimer's disease correlates with apoE uptake and intracellular Abeta stabilization. J Clin Invest 1997;100:310-320.
-
(1997)
J Clin Invest
, vol.100
, pp. 310-320
-
-
LaFerla, F.M.1
Troncoso, J.C.2
Strickland, D.K.3
-
51
-
-
0034736182
-
Quantitative histological analysis of amyloid deposition in Alzheimer's double transgenic mouse brain
-
Wengenack TM, Whelan S, Curran GL, et al. Quantitative histological analysis of amyloid deposition in Alzheimer's double transgenic mouse brain. Neuroscience 2000;101:939-944.
-
(2000)
Neuroscience
, vol.101
, pp. 939-944
-
-
Wengenack, T.M.1
Whelan, S.2
Curran, G.L.3
-
52
-
-
0034847176
-
Neurodegenerative changes associated with beta-amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes
-
Kurt MA, Davies DC, Kidd M, et al. Neurodegenerative changes associated with beta-amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes. Exp Neurol 2001;171:59-71.
-
(2001)
Exp Neurol
, vol.171
, pp. 59-71
-
-
Kurt, M.A.1
Davies, D.C.2
Kidd, M.3
-
53
-
-
0034009117
-
Immunohistochemical analysis of cerebral cortical and vascular lesions in the primate Microcebus murinus reveal distinct amyloid beta1-42 and beta1-40 immunoreactivity profiles
-
Mestre-Frances N, Keller E, Calenda A, et al. Immunohistochemical analysis of cerebral cortical and vascular lesions in the primate Microcebus murinus reveal distinct amyloid beta1-42 and beta1-40 immunoreactivity profiles. Neurobiol Dis 2000;7:1-8.
-
(2000)
Neurobiol Dis
, vol.7
, pp. 1-8
-
-
Mestre-Frances, N.1
Keller, E.2
Calenda, A.3
-
54
-
-
0030175625
-
Diffuse plaques in the cerebellum and corpus striatum in Down's syndrome contain amyloid beta protein (A beta) only in the form of A beta 42(43)
-
Mann DM, Iwatsubo T. Diffuse plaques in the cerebellum and corpus striatum in Down's syndrome contain amyloid beta protein (A beta) only in the form of A beta 42(43). Neurodegeneration 1996;5:115-120.
-
(1996)
Neurodegeneration
, vol.5
, pp. 115-120
-
-
Mann, D.M.1
Iwatsubo, T.2
-
55
-
-
0028919919
-
Amyloid beta protein (A beta) deposition: A beta 42(43) precedes A beta 40 in Down syndrome
-
Iwatsubo T, Mann DM, Odaka A, et al. Amyloid beta protein (A beta) deposition: a beta 42(43) precedes A beta 40 in Down syndrome. Ann Neurol 1995;37:294-299.
-
(1995)
Ann Neurol
, vol.37
, pp. 294-299
-
-
Iwatsubo, T.1
Mann, D.M.2
Odaka, A.3
-
56
-
-
0028169925
-
Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: Evidence that an initially deposited species is A beta 42(43)
-
Iwatsubo T, Odaka A, Suzuki N, et al. Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43). Neuron 1994;13:45-53.
-
(1994)
Neuron
, vol.13
, pp. 45-53
-
-
Iwatsubo, T.1
Odaka, A.2
Suzuki, N.3
-
57
-
-
0029923520
-
Association of A beta 40-positive senile plaques with microglial cells in the brains of patients with Alzheimer's disease and in non-demented aged individuals
-
Fukumoto H, Asami-Odaka A, Suzuki N, Iwatsubo T. Association of A beta 40-positive senile plaques with microglial cells in the brains of patients with Alzheimer's disease and in non-demented aged individuals. Neurodegeneration 1996;5:13-17.
-
(1996)
Neurodegeneration
, vol.5
, pp. 13-17
-
-
Fukumoto, H.1
Asami-Odaka, A.2
Suzuki, N.3
Iwatsubo, T.4
-
58
-
-
0030464914
-
Beta-amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease
-
Cummings BJ, Pike CJ, Shankle R, Cotman CW. Beta-amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease. Neurobiol Aging 1996;17:921-933.
-
(1996)
Neurobiol Aging
, vol.17
, pp. 921-933
-
-
Cummings, B.J.1
Pike, C.J.2
Shankle, R.3
Cotman, C.W.4
-
59
-
-
0014313861
-
The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects
-
Blessed G, Tomlinson BE, Roth M. The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. Br J Psychiatry 1968;114:797-811.
-
(1968)
Br J Psychiatry
, vol.114
, pp. 797-811
-
-
Blessed, G.1
Tomlinson, B.E.2
Roth, M.3
-
60
-
-
0025987048
-
Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
-
Terry RD, Masliah E, Salmon DP, et al. Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol 1991;30:572-580.
-
(1991)
Ann Neurol
, vol.30
, pp. 572-580
-
-
Terry, R.D.1
Masliah, E.2
Salmon, D.P.3
-
61
-
-
0038117796
-
Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline
-
Naslund J, Haroutunian V, Mohs R, et al. Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline. JAMA 2000;283:1571-1577.
-
(2000)
JAMA
, vol.283
, pp. 1571-1577
-
-
Naslund, J.1
Haroutunian, V.2
Mohs, R.3
-
62
-
-
0141448940
-
Behavioral and neurochemical characterization of transgenic mice carrying the human presenilin-1 gene with or without the leucine-to-proline mutation at codon 235
-
Huang XG, Yee BK, Nag S, et al. Behavioral and neurochemical characterization of transgenic mice carrying the human presenilin-1 gene with or without the leucine-to-proline mutation at codon 235. Exp Neurol 2003;183:673-681.
-
(2003)
Exp Neurol
, vol.183
, pp. 673-681
-
-
Huang, X.G.1
Yee, B.K.2
Nag, S.3
-
63
-
-
0037421111
-
Transgenic mice expressing the PS1-A246E mutation: Effects on spatial learning, exploration, anxiety, and motor coordination
-
Lalonde R, Qian S, Strazielle C. Transgenic mice expressing the PS1-A246E mutation: effects on spatial learning, exploration, anxiety, and motor coordination. Behav Brain Res 2003;138:71-79.
-
(2003)
Behav Brain Res
, vol.138
, pp. 71-79
-
-
Lalonde, R.1
Qian, S.2
Strazielle, C.3
-
64
-
-
0034622244
-
Spatial learning in transgenic mice expressing human presenilin 1 (PS1) transgenes
-
Janus C, D'Amelio S, Amitay O, et al. Spatial learning in transgenic mice expressing human presenilin 1 (PS1) transgenes. Neurobiol Aging 2000;21:541-549.
-
(2000)
Neurobiol Aging
, vol.21
, pp. 541-549
-
-
Janus, C.1
D'Amelio, S.2
Amitay, O.3
-
65
-
-
0036743625
-
Overexpression of hAPPswe impairs rewarded alternation and contextual fear conditioning in a transgenic mouse model of Alzheimer's disease
-
Corcoran KA, Lu Y, Turner RS, Maren S. Overexpression of hAPPswe impairs rewarded alternation and contextual fear conditioning in a transgenic mouse model of Alzheimer's disease. Learn Mem 2002;9:243-252.
-
(2002)
Learn Mem
, vol.9
, pp. 243-252
-
-
Corcoran, K.A.1
Lu, Y.2
Turner, R.S.3
Maren, S.4
-
66
-
-
0034095106
-
Enhanced synaptic potentiation in transgenic mice expressing presenilin 1 familial Alzheimer's disease mutation is normalized with a benzodiazepine
-
Zaman SH, Parent A, Laskey A, et al. Enhanced synaptic potentiation in transgenic mice expressing presenilin 1 familial Alzheimer's disease mutation is normalized with a benzodiazepine. Neurobiol Dis 2000;7:54-63.
-
(2000)
Neurobiol Dis
, vol.7
, pp. 54-63
-
-
Zaman, S.H.1
Parent, A.2
Laskey, A.3
-
67
-
-
0031821215
-
Synaptic transmission and hippocampal long-term potentiation in olfactory cyclic nucleotide-gated channel type 1 null mouse
-
Parent A, Schrader K, Munger SD, et al. Synaptic transmission and hippocampal long-term potentiation in olfactory cyclic nucleotide-gated channel type 1 null mouse. J Neurophysiol 1998;79:3295-3301.
-
(1998)
J Neurophysiol
, vol.79
, pp. 3295-3301
-
-
Parent, A.1
Schrader, K.2
Munger, S.D.3
-
68
-
-
0032032847
-
Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates Abeta1-42/43 expression
-
Qian S, Jiang P, Guan XM, et al. Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates Abeta1-42/43 expression. Neuron 1998;20:611-617.
-
(1998)
Neuron
, vol.20
, pp. 611-617
-
-
Qian, S.1
Jiang, P.2
Guan, X.M.3
-
69
-
-
0032032019
-
An Alzheimer's disease-linked PS1 variant rescues the developmental abnormalities of PS1-deficient embryos
-
Davis JA, Naruse S, Chen H, et al. An Alzheimer's disease-linked PS1 variant rescues the developmental abnormalities of PS1-deficient embryos. Neuron 1998;20:603-609.
-
(1998)
Neuron
, vol.20
, pp. 603-609
-
-
Davis, J.A.1
Naruse, S.2
Chen, H.3
|