Degeneration in vivo of rat hippocampal neurons by wild-type Alzheimer amyloid precursor protein overexpressed by adenovirus-mediated gene transfer

Journal of Neuroscience

Volumn 18, Issue 7, 1998, Pages 2387-2398

  Nishimura, Isao ^a   Uetsuki, Taichi ^a   Dani, Sergio U ^a   Ohsawa, Yoshiyuki ^b   Saito, Izumu ^c   Okamura, Hitoshi ^d   Uchiyama, Yasuo ^b   Yoshikawa, Kazuaki ^a  

^a OSAKA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Adenovirus vector; Alzheimer's disease; Amyloid precursor protein; Apoptosis; Hippocampus; Hypertonic mannitol; Microglia; Neurodegeneration; Synapse

Indexed keywords

AMYLOID PRECURSOR PROTEIN; VIRUS VECTOR;

ALZHEIMER DISEASE; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; GENE OVEREXPRESSION; GENE TRANSFER; HIPPOCAMPUS; MARKER GENE; NERVE CELL DEGENERATION; NEUROPATHOLOGY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT;

EID: 0032053984     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-07-02387.1998     Document Type: Article

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