Normal induction but accelerated decay of LTP in APP + PS1 transgenic mice

Neurobiology of Disease

Volumn 15, Issue 2, 2004, Pages 188-195

  Gureviciene, I ^a   Ikonen, S ^a   Gurevicius, K ^a   Sarkaki, A ^b   Van Groen, T ^a,c   Pussinen, R ^a   Ylinen, A ^a,c   Tanila, H ^a,c  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b Medical School of Basic Sciences   (Iran)

^c KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

Alzheimer's disease; Hippocampus; Long term potentiation; Spatial memory; Synaptic plasticity

Indexed keywords

ACCELERATION; ARTICLE; BEHAVIOR DISORDER; BIOACCUMULATION; BRAIN REGION; CONTROLLED STUDY; GENE MUTATION; GENOTYPE; HIPPOCAMPUS; HUMAN; LONG TERM POTENTIATION; MALE; MEDICAL RECORD; MEMORY DISORDER; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION; TASK PERFORMANCE; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; DENTATE GYRUS; DISEASE MODELS, ANIMAL; EXCITATORY POSTSYNAPTIC POTENTIALS; HIPPOCAMPUS; HUMANS; LONG-TERM POTENTIATION; MALE; MEMBRANE PROTEINS; MEMORY DISORDERS; MICE; MICE, TRANSGENIC; PHENOTYPE; PRESENILIN-1; SENILE PLAQUES; SYNAPTIC TRANSMISSION;

EID: 1542270770     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2003.11.011     Document Type: Article

References (36)

1. Bampton E.T., Gray R.A., Large C.H. Electrophysiological characterisation of the dentate gyrus in five inbred strains of mouse. Brain Res. 841:1999;123-134.
2. Borchelt D.R., Ratovitski T., Van Lare J., Lee M.K., Gonzales V., Jenkins N.A., Copeland N.G., Price D.L., Sisodia S.S. Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron. 19:1997;939-945.
3. Bourtchuladze R., Frenguelli B., Blendy J., Cioffi D., Schutz G., Silva A.J. Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein. Cell. 79:1994;59-68.
4. Chapman P.F., White G.L., Jones M.W., Cooper-Blacketer D., Marshall V.J., Irizarry M., Younkin L., Good M.A., Bliss T.V., Hyman B.T., Younkin S.G., Hsiao K.K. Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice. Nat. Neurosci. 2:1999;271-276.
5. Chen G., Chen K.S., Knox J., Inglis J., Bernard A., Martin S.J., Justice A., Mcconlogue L., Games D., Freedman S.B., Morris R.G. A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease. Nature. 408:2000;975-979.
6. Davis S., Vanhoutte P., Pages C., Caboche J., Laroche S. The MAPK/ERK cascade targets both Elk-1 and cAMP response element-binding protein to control long-term potentiation-dependent gene expression in the dentate gyrus in vivo. J. Neurosci. 20:2000;4563-4572.
7. Dineley K.T., Westerman M., Bui D., Bell K., Ashe K.H., Sweatt J.D. Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: in vitro and in vivo mechanisms related to Alzheimer's disease. J. Neurosci. 21:2001;4125-4133.
8. Fitzjohn S.M., Morton R.A., Kuenzi F., Rosahl T.W., Shearman M., Lewis H., Smith D., Reynolds D.S., Davies C.H., Collingridge G.L., Seabrook G.R. Age-related impairment of synaptic transmission but normal long-term potentiation in transgenic mice that overexpress the human APP695SWE mutant form of amyloid precursor protein. J. Neurosci. 21:2001;4691-4698.
9. Frey U., Huang Y.Y., Kandel E.R. Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons. Science. 260:1993;1661-1664.
10. Guntern R., Bouras C., Hof P.R., Vallet P.G. An improved thioflavine S method for staining neurofibrillary tangles and senile plaques in Alzheimer's disease. Experientia. 48:1992;8-10.
11. Guzowski J.F., Lyford G.L., Stevenson G.D., Houston F.P., Mcgaugh J.L., Worley P.F., Barnes C.A. Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory. J. Neurosci. 20:2000;3993-4001.
12. Hsia A.Y., Masliah E., Mcconlogue L., Yu G.Q., Tatsuno G., Hu K., Kholodenko D., Malenka R.C., Nicoll R.A., Mucke L. Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models. Proc. Natl. Acad. Sci. U. S. A. 96:1999;3228-3233.
13. Hsiao K., Chapman P., Nilsen S., Eckman C., Harigaya Y., Younkin S., Yang F., Cole G. Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science. 274:1996;99-102.
14. Ida N., Masters C.L., Beyreuther K. Rapid cellular uptake of Alzheimer amyloid betaA4 peptide by cultured human neuroblastoma cells. FEBS Lett. 394:1996;174-178.
15. Jones M.W., Errington M.L., French P.J., Fine A., Bliss T.V., Garel S., Charnay P., Bozon B., Laroche S., Davis S. A requirement for the immediate early gene Zif268 in the expression of late LTP and long-term memories. Nat. Neurosci. 4:2001;289-296.
16. Kadish I., Pradier L., Van Groen T. Transgenic mice expressing the human presenilin 1 gene demonstrate enhanced hippocampal reorganization following entorhinal cortex lesions. Brain Res. Bull. 57:2002;587-594.
17. Kawarabayashi T., Younkin L.H., Saido T.C., Shoji M., Ashe K.H., Younkin S.G. Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease. J. Neurosci. 21:2001;372-381.
18. Koistinaho M., Ort M., Cimadevilla J.M., Vondrous R., Cordell B., Koistinaho J., Bures J., Higgins L.S. Specific spatial learning deficits become severe with age in beta-amyloid precursor protein transgenic mice that harbor diffuse beta-amyloid deposits but do not form plaques. Proc. Natl. Acad. Sci. U. S. A. 98:2001;14675-14680.
19. Larson J., Lynch G., Games D., Seubert P. Alterations in synaptic transmission and long-term potentiation in hippocampal slices from young and aged PDAPP mice. Brain Res. 840:1999;23-35.
20. Lazarov O., Lee M., Peterson D.A., Sisodia S.S. Evidence that synaptically released beta-amyloid accumulates as extracellular deposits in the hippocampus of transgenic mice. J. Neurosci. 22:2002;9785-9793.
21. Liu L., Ikonen S., Heikkinen T., Heikkilä M., Puoliväli J., Van Groen T., Tanila H. Effects of fimbria-fornix lesion and amyloid pathology on spatial learning and memory in transgenic APP + PS1 mice. Behav. Brain Res. 134:2002;433-445.
22. Moechars D., Dewachter I., Lorent K., Reverse D., Baekelandt V., Naidu A., Tesseur I., Spittaels K., Haute C.V., Checler F., Godaux E., Cordell B., Van Leuven F. Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain. J. Biol. Chem. 274:1999;6483-6492.
23. Nalbantoglu J., Tirado-Santiago G., Lahsaini A., Poirier J., Goncalves O., Verge G., Momoli F., Welner S.A., Massicotte G., Julien J.P., Shapiro M.L. Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein. Nature. 387:1997;500-505.
24. Otani S., Abraham W.C. Inhibition of protein synthesis in the dentate gyrus, but not the entorhinal cortex, blocks maintenance of long-term potentiation in rats. Neurosci. Lett. 106:1989;175-180.
25. Parent A., Linden D.J., Sisodia S.S., Borchelt D.R. Synaptic transmission and hippocampal long-term potentiation in transgenic mice expressing FAD-linked presenilin 1. Neurobiol. Dis. 6:1999;56-62.
26. Price D.L., Sisodia S.S. Mutant genes in familial Alzheimer's disease and transgenic models. Annu. Rev. Neurosci. 21:1998;479-505.
27. Puoliväli J., Wang J., Heikkinen T., Heikkila M., Tapiola T., Van Groen T., Tanila H. Hippocampal Abeta42 levels correlate with spatial memory deficit in APP and PS1 double transgenic mice. Neurobiol. Dis. 9:2002;339-347.
28. Selkoe D.J. Alzheimer's disease: genes, proteins, and therapy. Physiol. Rev. 81:2001;741-766.
29. Stephan A., Laroche S., Davis S. Generation of aggregated beta-amyloid in the rat hippocampus impairs synaptic transmission and plasticity and causes memory deficits. J. Neurosci. 21:2001;5703-5714.
30. Tong L., Thornton P.L., Balazs R., Cotman C.W. Beta-amyloid-(1-42) impairs activity-dependent cAMP-response element-binding protein signaling in neurons at concentrations in which cell survival is not compromised. J. Biol. Chem. 276:2001;17301-17306.
31. Vitolo O., Sant'Angelo A., Costanzo V., Battaglia F., Arancio O., Shelanski M. Amyloid b-peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling. Proc. Natl. Acad. Sci. 99:2002;13217-13221.
32. Walsh D.M., Klyubin I., Fadeeva J.V., Cullen W.K., Anwyl R., Wolfe M.S., Rowan M.J., Selkoe D.J. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature. 416:2002;535-539.
33. Wang J., Ikonen S., Gurevicius K., Van Groen T., Tanila H. Alteration of cortical EEG in mice carrying mutated human APP transgene. Brain Res. 943:2002;181-190.
34. Welsh K.A., Butters N., Hughes J.P., Mohs R.C., Heyman A. Detection and staging of dementia in Alzheimer's disease. Use of the neuropsychological measures developed for the Consortium to Establish a Registry for Alzheimer's Disease. Arch. Neurol. 49:1992;448-452.
35. Westerman M.A., Cooper-Blacketer D., Mariash A., Kotilinek L., Kawarabayashi T., Younkin L.H., Carlson G.A., Younkin S.G., Ashe K.H. The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease. J. Neurosci. 22:2002;1858-1867.
36. Ying S.W., Futter M., Rosenblum K., Webber M.J., Hunt S.P., Bliss T.V., Bramham C.R. Brain-derived neurotrophic factor induces long-term potentiation in intact adult hippocampus: requirement for ERK activation coupled to CREB and upregulation of Arc synthesis. J. Neurosci. 22:2002;1532-1540.