Similar levels of long-term potentiation in amyloid precursor protein - null and wild-type mice in the CA1 region of picrotoxin treated slices

Neuroscience Letters

Volumn 288, Issue 1, 2000, Pages 9-12

  Fitzjohn, Stephen M ^a   Morton, Robin A ^a   Kuenzi, Frederick ^a,b   Davies, Ceri H ^c   Seabrook, Guy R ^b   Collingridge, Graham L ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Aminobutyric acid; Alzheimer's disease; Amyloid precursor protein; Long term potentiation

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; AMYLOID PRECURSOR PROTEIN; PICROTOXIN;

ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPUS; LONG TERM POTENTIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RECEPTOR BLOCKING; STIMULUS RESPONSE; SYNAPTIC INHIBITION; TETANUS; THETA RHYTHM;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CENTRAL NERVOUS SYSTEM STIMULANTS; ELECTRIC STIMULATION; EXCITATORY POSTSYNAPTIC POTENTIALS; GAMMA-AMINOBUTYRIC ACID; HIPPOCAMPUS; LONG-TERM POTENTIATION; MICE; MICE, KNOCKOUT; NEURAL INHIBITION; ORGAN CULTURE TECHNIQUES; PICROTOXIN;

EID: 0034617378     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(00)01204-0     Document Type: Article

References (9)

1. Anderson W.W., Collingridge G.L. A data acquisition program for on-line analysis of long-term potentiation and long-term depression. Soc. Neurosci. Abstr. 23:1997;665.
2. Bliss T.V.P., Collingridge G.L. A synaptic model of memory: long-term potentiation in the hippocampus. Nature. 361:1993;31-39.
3. B autoreceptors in rat hippocampus. J. Physiol. 496:1996;451-470.
4. B autoreceptors regulate the induction of LTP. Nature. 349:1991;609-611.
5. Dawson G.R., Seabrook G.R., Zheng H., Smith D.W., Graham S., O'Dowd G., Bowey B.J., Boyce S., Trumbauer M.E., Chen H.Y., Van der Ploeg L.H.T., Sirinathsinghji D.J.S. Age-related cognitive deficits, impaired long-term potentiation and reduction in synaptic marker density in mice lacking the β-amyloid precursor protein. Neuroscience. 90:1999;1-13.
6. Nosten-Bertrand M., Errington M.L., Murphy K.P., Tokugawa Y., Barboni E., Kozlova E., Michalovich D., Morris R.G., Silver J., Stewart C.L., Bliss T.V., Morris R.J. Normal spatial learning despite regional inhibition of LTP in mice lacking Thy-1. Nature. 379:1996;826-829.
7. B-receptor antagonists on long-term potentiation. Naunyn-Schmiedebergs Arch. Pharmacol. 342:1990;194-197.
8. Seabrook G.R., Rosahl T.W. Transgenic animals relevant to Alzheimer's disease. Neuropharmacology. 38:1999;1-17.
9. Seabrook G.R., Smith D.W., Bowery B.J., Easter A., Reynolds T., Fitzjohn S.M., Morton R.A., Zheng H., Dawson G.R., Sirinathsinghji D.J.S., Davies C.H., Collingridge G.L., Hill R.G. Mechanisms contributing to the deficits in hippocampal synaptic plasticity in mice lacking amyloid precursor protein. Neuropharmacology. 38:1999;349-359.