Aβ oligomer-mediated long-term potentiation impairment involves protein phosphatase 1-dependent mechanisms

Journal of Neuroscience

Volumn 27, Issue 29, 2007, Pages 7648-7653

  Knobloch, Marlen ^a   Farinelli, Mélissa ^a   Konietzko, Uwe ^a   Nitsch, Roger M ^a   Mansuy, Isabelle M ^a,b  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b ETH ZURICH   (Switzerland)

Author keywords

A peptide; Alzheimer's disease; Impairment; LTP; Oligomers; PP1

Indexed keywords

AMYLOID A PROTEIN; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; OLIGOMER; PHOSPHOPROTEIN PHOSPHATASE 1; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE TYPE 2; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; PHOSPHOPROTEIN PHOSPHATASE; PRESENILIN 1; PROTEIN KINASE (CALCIUM,CALMODULIN); SECRETASE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; EXPERIMENTAL MODEL; GENE MUTATION; GENETIC MANIPULATION; IN VITRO SELECTION; IN VIVO CULTURE; LONG TERM POTENTIATION; MOLECULAR DYNAMICS; MOUSE; MOUSE STRAIN; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE; AGE; ANALYSIS OF VARIANCE; ANIMAL; CHEMISTRY; CYTOLOGY; DRUG EFFECT; ELECTROSTIMULATION; EXCITATORY POSTSYNAPTIC POTENTIAL; GENE EXPRESSION REGULATION; GENETICS; HIPPOCAMPUS; HUMAN; IN VITRO STUDY; METABOLISM; METHODOLOGY; NERVE CELL; PATCH CLAMP; PHYSIOLOGY; RADIATION EXPOSURE; RADIATION RESPONSE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

AGE FACTORS; AMYLOID BETA-PROTEIN; AMYLOID PRECURSOR PROTEIN SECRETASES; ANALYSIS OF VARIANCE; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTRIC STIMULATION; EXCITATORY POSTSYNAPTIC POTENTIALS; GENE EXPRESSION REGULATION; HIPPOCAMPUS; HUMANS; LONG-TERM POTENTIATION; MICE; MICE, TRANSGENIC; MICROSCOPY, ELECTRON, TRANSMISSION; NEURONS; PATCH-CLAMP TECHNIQUES; PHOSPHOPROTEIN PHOSPHATASE; PRESENILIN-1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 34447649563     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0395-07.2007     Document Type: Article

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