Amyloid β-peptide inhibition of the PKA/CREB pathway and long-term potentiation: Reversibility by drugs that enhance cAMP signaling

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 20, 2002, Pages 13217-13221

  Vitolo, Ottavio V ^a   Sant'Angelo, Antonino ^c   Costanzo, Vincenzo ^b   Battaglia, Fortunato ^c   Arancio, Ottavio ^c   Shelanski, Michael ^a,b  

^a NewYork Presbyterian Hospital   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FORSKOLIN; GLUTAMIC ACID; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHOSPHODIESTERASE INHIBITOR; ROLIPRAM;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME INACTIVATION; FETUS; HIPPOCAMPUS; LONG TERM POTENTIATION; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

AMYLOID BETA-PROTEIN; ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ELECTROPHYSIOLOGY; HIPPOCAMPUS; LONG-TERM POTENTIATION; MODELS, BIOLOGICAL; NEURONS; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TIME FACTORS;

ANIMALIA;

EID: 0036792096     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.172504199     Document Type: Article

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