Non-fibrillar β-amyloid abates spike-timing-dependent synaptic potentiation at excitatory synapses in layer 2/3 of the neocortex by targeting postsynaptic AMPA receptors

European Journal of Neuroscience

Volumn 23, Issue 8, 2006, Pages 2035-2047

  Shemer, Isaac ^a   Holmgren, Carl ^a   Min, Rogier ^b   Fülöp, Livia ^c   Zilberter, Misha ^a   Sousa, Kyle M ^a   Farkas, Tamás ^c   Härtig, Wolfgang ^d   Penke, Botond ^c   Burnashev, Nail ^b   Tanila, Heikki ^e   Zilberter, Yuri ^a,f   Harkany, Tibor ^a,f  

^a KAROLINSKA INSTITUTE   (Sweden)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

^c UNIVERSITY OF SZEGED   (Hungary)

^d UNIVERSITY OF LEIPZIG   (Germany)

^e UNIVERSITY OF EASTERN FINLAND   (Finland)

^f Turing Center for Living Systems CENTURI Aix Marseille University   (France)

Author keywords

Alzheimer's disease; Excitatory synapse; Neocortex; Synaptic plasticity

Indexed keywords

AMPA RECEPTOR; AMYLOID BETA PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NONFIBRILLAR BETA AMYLOID; POSTSYNAPTIC RECEPTOR; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; MALE; MOUSE; NEOCORTEX; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NERVE CONDUCTION; NERVE EXCITABILITY; NERVE STIMULATION; NEUROPATHOLOGY; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; PYRAMIDAL NERVE CELL; RAT; RECEPTOR DOWN REGULATION; SYNAPSE; SYNAPTIC POTENTIAL;

ACTION POTENTIALS; AGE FACTORS; ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANIMALS, NEWBORN; DISEASE MODELS, ANIMAL; ELECTRIC STIMULATION; EXCITATORY AMINO ACID AGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, TRANSGENIC; N-METHYLASPARTATE; NEOCORTEX; PATCH-CLAMP TECHNIQUES; PYRAMIDAL CELLS; RECEPTORS, AMPA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SYNAPSES; TIME FACTORS;

EID: 33645989995     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2006.04733.x     Document Type: Article

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