-
1
-
-
0025296205
-
Processing of Alzheimer β/A4 amyloid precursor protein: Modulation by agents that regulate protein phosphorylation
-
J.D. Buxbaum, S.E. Gandy, P. Cicchetti, M.E. Ehrlich, A.J. Czenik, R.P. Fracasso, T.V. Ramabhadran, A.J. Unterbeck, and P. Greengard Processing of Alzheimer β/A4 amyloid precursor protein: Modulation by agents that regulate protein phosphorylation Proc. Natl. Acad. Sci. U.S.A. 87 1990 6003 6006
-
(1990)
Proc. Natl. Acad. Sci. U.S.A.
, vol.87
, pp. 6003-6006
-
-
Buxbaum, J.D.1
Gandy, S.E.2
Cicchetti, P.3
Ehrlich, M.E.4
Czenik, A.J.5
Fracasso, R.P.6
Ramabhadran, T.V.7
Unterbeck, A.J.8
Greengard, P.9
-
2
-
-
14444272986
-
Evidence that tumor necrosis factor α converting enzyme is involved in regulated α-secretase cleavage of the Alzheimer amyloid protein precursor
-
J.D. Buxbaum, K.N. Liu, Y. Luo, J.L. Slack, K.L. Stocking, J.J. Peschon, R.S. Johnson, B.J. Castner, D.P. Cerretti, and R.A. Black Evidence that tumor necrosis factor α converting enzyme is involved in regulated α-secretase cleavage of the Alzheimer amyloid protein precursor J. Biol. Chem. 273 1998 27765 27767
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 27765-27767
-
-
Buxbaum, J.D.1
Liu, K.N.2
Luo, Y.3
Slack, J.L.4
Stocking, K.L.5
Peschon, J.J.6
Johnson, R.S.7
Castner, B.J.8
Cerretti, D.P.9
Black, R.A.10
-
3
-
-
0029379605
-
Processing of the β-amyloid precursor protein and its regulation in Alzheimer's disease
-
F. Checler Processing of the β-amyloid precursor protein and its regulation in Alzheimer's disease J. Neurochem. 65 1995 1431 1444
-
(1995)
J. Neurochem.
, vol.65
, pp. 1431-1444
-
-
Checler, F.1
-
4
-
-
0030739716
-
Novel β-secretase cleavage of β-amyloid precursor protein in the endoplasmic reticulum/intermediate compartment of NT2N cells
-
A.S.C. Chyung, B.D. Greenberg, D.G. Cook, and R.W. Doms Novel β-secretase cleavage of β-amyloid precursor protein in the endoplasmic reticulum/intermediate compartment of NT2N cells J. Cell Biol. 138 1997 671 680
-
(1997)
J. Cell Biol.
, vol.138
, pp. 671-680
-
-
Chyung, A.S.C.1
Greenberg, B.D.2
Cook, D.G.3
Doms, R.W.4
-
5
-
-
0030769092
-
Alzheimer's Aβ (1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells
-
A.G. Cook, M.S. Forman, J.C. Sung, S. Leight, D.L. Kolson, T. Iwatsubo, V.M.-Y. Lee, and R.W. Doms Alzheimer's Aβ (1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells Nat. Med. 3 1997 1021 1023
-
(1997)
Nat. Med.
, vol.3
, pp. 1021-1023
-
-
Cook, A.G.1
Forman, M.S.2
Sung, J.C.3
Leight, S.4
Kolson, D.L.5
Iwatsubo, T.6
Lee, V.M.-Y.7
Doms, R.W.8
-
6
-
-
0024308993
-
Brefeldin a redistributes resident and itinerant Golgi proteins to the endoplasmic reticulum
-
R.W. Doms, G. Russ, and J.W. Yewdell Brefeldin A redistributes resident and itinerant Golgi proteins to the endoplasmic reticulum J. Cell Biol. 109 1989 61 72
-
(1989)
J. Cell Biol.
, vol.109
, pp. 61-72
-
-
Doms, R.W.1
Russ, G.2
Yewdell, J.W.3
-
7
-
-
0028900634
-
Immunocytochemical localization of eight protein kinase C isozymes overexpressed in NIH 3T3 fibroblasts. Isoform-specific association with microfilaments, Golgi, endoplasmic reticulum, and nuclear and cell membranes
-
J.A. Goodnight, H. Mischak, W. Kolch, and J.F. Mushinski Immunocytochemical localization of eight protein kinase C isozymes overexpressed in NIH 3T3 fibroblasts. Isoform-specific association with microfilaments, Golgi, endoplasmic reticulum, and nuclear and cell membranes J. Biol. Chem. 270 1995 9991 10001
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 9991-10001
-
-
Goodnight, J.A.1
Mischak, H.2
Kolch, W.3
Mushinski, J.F.4
-
8
-
-
0026735070
-
Targeting of cell-surface β-amyloid precursor protein to lysosomes: Alternative processing into amyloid-bearing fragments
-
C. Haass, E.H. Koo, A. Mellon, A.Y. Hung, and D.J. Selkoe Targeting of cell-surface β-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments Nature 357 1992 500 503
-
(1992)
Nature
, vol.357
, pp. 500-503
-
-
Haass, C.1
Koo, E.H.2
Mellon, A.3
Hung, A.Y.4
Selkoe, D.J.5
-
9
-
-
0028866435
-
The Swedish mutation causes early-onset Alzheimer's disease by β-secretase cleavage within the secretory pathway
-
C. Haass, C.A. Lemere, A. Capell, M. Citron, P. Seubert, D. Schenk, L. Lannfelt, and D.J. Selkoe The Swedish mutation causes early-onset Alzheimer's disease by β-secretase cleavage within the secretory pathway Nat. Med. 12 1995 1291 1296
-
(1995)
Nat. Med.
, vol.12
, pp. 1291-1296
-
-
Haass, C.1
Lemere, C.A.2
Capell, A.3
Citron, M.4
Seubert, P.5
Schenk, D.6
Lannfelt, L.7
Selkoe, D.J.8
-
10
-
-
0033458064
-
Intracellular biology of Alzheimer's disease amyloid beta peptide
-
T. Hartmann Intracellular biology of Alzheimer's disease amyloid beta peptide Eur. Arch. Psychiatry Clin. Neurosci. 249 1999 291 298
-
(1999)
Eur. Arch. Psychiatry Clin. Neurosci.
, vol.249
, pp. 291-298
-
-
Hartmann, T.1
-
11
-
-
0030769091
-
Distinct sites of intracellular production for Alzheimer's disease Aβ40/42 peptides
-
T. Hartmann, S.C. Bieger, B. Bruhl, P.J. Tienari, N. Ida, D. Allsop, G.W. Roberts, C.L. Masters, C.G. Dotti, K. Unsicker, and K. Beyreuther Distinct sites of intracellular production for Alzheimer's disease Aβ40/42 peptides Nat. Med. 3 1997 1016 1020
-
(1997)
Nat. Med.
, vol.3
, pp. 1016-1020
-
-
Hartmann, T.1
Bieger, S.C.2
Bruhl, B.3
Tienari, P.J.4
Ida, N.5
Allsop, D.6
Roberts, G.W.7
Masters, C.L.8
Dotti, C.G.9
Unsicker, K.10
Beyreuther, K.11
-
12
-
-
0033569653
-
Membrane-anchored metalloprotease MDC9 has an α-secretase activity responsible for processing the amyloid precursor protein
-
H. Koike, S. Tomioka, H. Sorimachi, T.C. Saido, K. Maruyama, A. Okuyama, A. Fujisawa-Sehara, S. Ohno, K. Suzuki, and S. Ishiura Membrane-anchored metalloprotease MDC9 has an α-secretase activity responsible for processing the amyloid precursor protein Biochem. J. 343 1999 371 375
-
(1999)
Biochem. J.
, vol.343
, pp. 371-375
-
-
Koike, H.1
Tomioka, S.2
Sorimachi, H.3
Saido, T.C.4
Maruyama, K.5
Okuyama, A.6
Fujisawa-Sehara, A.7
Ohno, S.8
Suzuki, K.9
Ishiura, S.10
-
13
-
-
0027484116
-
The Alzheimer β-amyloid protein precursor/protease nexin-II is cleaved by secretase in a trans-Golgi secretory compartment in human neuroglioma cells
-
S.L. Kuentzel, S.M. Ali, R.A. Altman, B.D. Greenberg, and T.J. Raub The Alzheimer β-amyloid protein precursor/protease nexin-II is cleaved by secretase in a trans-Golgi secretory compartment in human neuroglioma cells Biochem. J. 295 1993 367 378
-
(1993)
Biochem. J.
, vol.295
, pp. 367-378
-
-
Kuentzel, S.L.1
Ali, S.M.2
Altman, R.A.3
Greenberg, B.D.4
Raub, T.J.5
-
14
-
-
0033616716
-
Constitutive and regulated α-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease
-
S. Lammich, E. Kojro, R. Postina, S. Gilbert, R. Pfeiffer, M. Jasionowski, C. Haass, and F. Fahrenholz Constitutive and regulated α-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease Proc. Natl. Acad. Sci. U.S.A. 96 1999 3922 3927
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 3922-3927
-
-
Lammich, S.1
Kojro, E.2
Postina, R.3
Gilbert, S.4
Pfeiffer, R.5
Jasionowski, M.6
Haass, C.7
Fahrenholz, F.8
-
15
-
-
0037022828
-
Glu11 site cleavage and N-terminally truncated Aβ production upon BACE overexpression
-
K. Liu, R.W. Doms, and V.M. Lee Glu11 site cleavage and N-terminally truncated Aβ production upon BACE overexpression Biochemistry 41 2002 3128 3136
-
(2002)
Biochemistry
, vol.41
, pp. 3128-3136
-
-
Liu, K.1
Doms, R.W.2
Lee, V.M.3
-
16
-
-
0030779677
-
Cellular actions of β-amyloid precursor protein and its soluble and fibrillogenic derivatives
-
M.P. Mattson Cellular actions of β-amyloid precursor protein and its soluble and fibrillogenic derivatives Physiol. Rev. 77 1997 1081 1132
-
(1997)
Physiol. Rev.
, vol.77
, pp. 1081-1132
-
-
Mattson, M.P.1
-
17
-
-
0027365520
-
Light and electron microscopic immunocytochemical localization of PKC delta immunoreactivity in the rat central nervous system
-
I. Merchenthaler, Z. Liposits, J.J. Reid, and W.C. Wetsel Light and electron microscopic immunocytochemical localization of PKC delta immunoreactivity in the rat central nervous system J. Comp. Neurol. 336 1993 378 399
-
(1993)
J. Comp. Neurol.
, vol.336
, pp. 378-399
-
-
Merchenthaler, I.1
Liposits, Z.2
Reid, J.J.3
Wetsel, W.C.4
-
18
-
-
0026665014
-
Evidence for intracellular cleavage of the Alzheimer's amyloid precursor in PC12 cells
-
K. Sambamurti, J. Shioi, J.P. Anderson, M.A. Pappolla, and N.K. Robakis Evidence for intracellular cleavage of the Alzheimer's amyloid precursor in PC12 cells J. Neurosci. Res. 33 1992 319 329
-
(1992)
J. Neurosci. Res.
, vol.33
, pp. 319-329
-
-
Sambamurti, K.1
Shioi, J.2
Anderson, J.P.3
Pappolla, M.A.4
Robakis, N.K.5
-
19
-
-
0026029619
-
Identification of the region including the epitope for a monoclonal antibody which can neutralize human parvovirus B19
-
H. Sato, J. Hirata, M. Furukawa, N. Kuroda, H. Shiraki, Y. Maeda, and K. Okochi Identification of the region including the epitope for a monoclonal antibody which can neutralize human parvovirus B19 J. Virol. 65 1991 1667 1672
-
(1991)
J. Virol.
, vol.65
, pp. 1667-1672
-
-
Sato, H.1
Hirata, J.2
Furukawa, M.3
Kuroda, N.4
Shiraki, H.5
Maeda, Y.6
Okochi, K.7
-
20
-
-
0032032493
-
Turnover of amyloid β-protein in mouse brain and acute reduction of its level by phorbol ester
-
M.J. Savage, S.P. Trusko, D.S. Howland, L.R. Pinsker, S. Mistretta, A.G. Reaume, B.D. Greenberg, R. Siman, and R.W. Scott Turnover of amyloid β-protein in mouse brain and acute reduction of its level by phorbol ester J. Neurosci. 18 1998 1743 1752
-
(1998)
J. Neurosci.
, vol.18
, pp. 1743-1752
-
-
Savage, M.J.1
Trusko, S.P.2
Howland, D.S.3
Pinsker, L.R.4
Mistretta, S.5
Reaume, A.G.6
Greenberg, B.D.7
Siman, R.8
Scott, R.W.9
-
21
-
-
0035066332
-
Alzheimer's disease: Genes, proteins, and therapy
-
D.J. Selkoe Alzheimer's disease: genes, proteins, and therapy Physiol. Rev. 81 2001 741 766
-
(2001)
Physiol. Rev.
, vol.81
, pp. 741-766
-
-
Selkoe, D.J.1
-
22
-
-
0026721943
-
β-Amyloid precursor protein cleavage by a membrane-bound protease
-
S.S. Sisodia β-Amyloid precursor protein cleavage by a membrane-bound protease Proc. Natl. Acad. Sci. U.S.A. 89 1992 6075 6079
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 6075-6079
-
-
Sisodia, S.S.1
-
23
-
-
0034723418
-
Protein kinase C-dependent α-secretase competes with β-secretase for cleavage of amyloid-β precursor protein in the trans-Golgi network
-
D.M. Skovronsky, D.B. Moore, M.E. Milla, R.W. Doms, and V.M. Lee Protein kinase C-dependent α-secretase competes with β-secretase for cleavage of amyloid-β precursor protein in the trans-Golgi network J. Biol. Chem. 275 2000 2568 2575
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2568-2575
-
-
Skovronsky, D.M.1
Moore, D.B.2
Milla, M.E.3
Doms, R.W.4
Lee, V.M.5
-
24
-
-
0024550204
-
Identification, biogenesis, and localization of precursor of Alzheimer's disease A4 amyloid protein
-
A. Weidemann, G. Konig, D. Bunke, P. Fischer, J.M. Salbaum, C.L. Masters, and K. Beyreuther Identification, biogenesis, and localization of precursor of Alzheimer's disease A4 amyloid protein Cell 57 1989 115 126
-
(1989)
Cell
, vol.57
, pp. 115-126
-
-
Weidemann, A.1
Konig, G.2
Bunke, D.3
Fischer, P.4
Salbaum, J.M.5
Masters, C.L.6
Beyreuther, K.7
-
25
-
-
0030952217
-
Intracellular generation and accumulation of amyloid β-peptide terminating at amino acid 42
-
C. Wild-Bode, T. Yamazaki, A. Capell, U. Leimer, H. Steiner, Y. Ihara, and C. Haass Intracellular generation and accumulation of amyloid β-peptide terminating at amino acid 42 J. Bio. Chem. 272 1997 16085 16088
-
(1997)
J. Bio. Chem.
, vol.272
, pp. 16085-16088
-
-
Wild-Bode, C.1
Yamazaki, T.2
Capell, A.3
Leimer, U.4
Steiner, H.5
Ihara, Y.6
Haass, C.7
-
26
-
-
0036724204
-
Iron (III) induces aggregation of hyperphosphorylated tau and its reduction to iron (II) reverses the aggregation: Implications in the formation of neurofibrillary tangles of Alzheimer's disease
-
A. Yamamoto, R.-W. Shin, K. Hasegawa, H. Naiki, H. Sato, Y. Yoshimasu, and T. Kitamoto Iron (III) induces aggregation of hyperphosphorylated tau and its reduction to iron (II) reverses the aggregation: implications in the formation of neurofibrillary tangles of Alzheimer's disease J. Neurochem. 82 2002 1137 1147
-
(2002)
J. Neurochem.
, vol.82
, pp. 1137-1147
-
-
Yamamoto, A.1
Shin, R.-W.2
Hasegawa, K.3
Naiki, H.4
Sato, H.5
Yoshimasu, Y.6
Kitamoto, T.7
-
27
-
-
0028177688
-
Secretion of β-amyloid precursor protein involves multiple cleavage sites
-
Z. Zhong, J. Higaki, K. Murakami, Y. Wang, R. Catalano, D. Quon, and B. Cordell Secretion of β-amyloid precursor protein involves multiple cleavage sites J. Biol. Chem. 269 1994 627 632
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 627-632
-
-
Zhong, Z.1
Higaki, J.2
Murakami, K.3
Wang, Y.4
Catalano, R.5
Quon, D.6
Cordell, B.7
|