Endogenous secreted amyloid precursor protein-α regulates hippocampal NMDA receptor function, long-term potentiation and spatial memory

Neurobiology of Disease

Volumn 31, Issue 2, 2008, Pages 250-260

  Taylor, Chanel J ^a   Ireland, David R ^a   Ballagh, Irene ^a   Bourne, Katie ^a,b   Marechal, Nicola M ^a   Turner, Paul R ^b   Bilkey, David K ^a   Tate, Warren P ^a,b   Abraham, Wickliffe C ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

a disintegrin and metalloprotease; AMPA receptor; Dentate gyrus; Long term potentiation; NMDA receptor; Secreted APP ; Secreted APP ; Spatial memory; TAPI 1

Indexed keywords

ADAM PROTEIN; ALPHA SECRETASE; AMPA RECEPTOR; AMYLOID A PROTEIN; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENTATE NUCLEUS; EXCITATORY POSTSYNAPTIC POTENTIAL; GRANULE CELL; HIPPOCAMPUS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LONG TERM POTENTIATION; MALE; NERVE CELL PLASTICITY; NEUROMODULATION; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN SECRETION; RAT; SPATIAL MEMORY;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ANTIBODIES; DIPEPTIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GLUTAMIC ACID; HIPPOCAMPUS; HYDROXAMIC ACIDS; LONG-TERM POTENTIATION; MALE; MEMORY; MEMORY DISORDERS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; RECOMBINANT FUSION PROTEINS; SPACE PERCEPTION; SYNAPTIC TRANSMISSION;

EID: 47149092572     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2008.04.011     Document Type: Article

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