Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

Nature

Volumn 391, Issue 6665, 1998, Pages 387-390

  De Strooper, Bart ^a   Saftig, Paul ^c   Craessaerts, Katleen ^a   Vanderstichele, Hugo ^b   Guhde, Gundula ^c   Annaert, Wim ^a   Von Figura, Kurt ^c   Van Leuven, Fred ^a  

^a Center for Human Genetics   (Belgium)

^b INNOGENETICS   (Belgium)

^c UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; PRESENILIN 1;

ALZHEIMER DISEASE; ANIMAL MODEL; ARTICLE; DEGENERATIVE DISEASE; EMBRYO; ENZYME ACTIVITY; MOUSE; NERVE CELL CULTURE; NEUROLOGIC DISEASE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN DEGRADATION;

AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; CELLS, CULTURED; ENDOPEPTIDASES; HUMANS; MEMBRANE PROTEINS; MICE; NEURONS; PEPTIDE FRAGMENTS; POINT MUTATION; PRESENILIN-1; PROTEIN PROCESSING, POST-TRANSLATIONAL;

EID: 0032556859     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/34910     Document Type: Article

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