Accelerating amyloid-β fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models

Journal of Biological Chemistry

Volumn 282, Issue 33, 2007, Pages 23818-23828

  Cheng, Irene H ^a,b   Scearce Levie, Kimberly ^a,b   Legleiter, Justin ^a,b   Palop, Jorge J ^a,b   Gerstein, Hilary ^a   Bien Ly, Nga ^a   Puoliväli, Jukka ^a,b,d   Lesné, Sylvain ^c   Ashe, Karen H ^c   Muchowski, Paul J ^a,b   Mucke, Lennart ^a,b,e  

^a GLADSTONE INSTITUTE OF NEUROLOGICAL DISEASE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^d Cerebricon Limited   (Finland)

^e NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; MUTAGENESIS; NEUROLOGY; OLIGOMERS;

ALZHEIMER DISEASE; AMYLOID FIBRILLIZATION; HUMAN AMYLOID PRECURSOR PROTEIN (HAPP);

PROTEINS;

AMYLOID BETA PROTEIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARCTIC; ARTICLE; BEHAVIOR; CONTROLLED STUDY; GENE MUTATION; IN VITRO STUDY; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE; WILD TYPE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; HUMANS; KINETICS; MICE; MICE, TRANSGENIC; MUTATION; OLIGOPEPTIDES;

MUS; MUS MUSCULUS;

EID: 34548258322     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M701078200     Document Type: Article

References (76)

1. Walsh, D. M., and Selkoe, D. J. (2004) Neuron 44, 181-193
2. Tanzi, R., and Bertram, L. (2005) Cell 120, 545-555
3. Skovronsky, D. M., Lee, V. M.-Y., and Trojanowski, J. Q. (2006) Annu. Rev. Pathol. Mech. Dis. 1, 151-170
4. Hebert, L., Scherr, P., Bienias, J., Bennett, D., and Evans, D. (2003) Arch. Neurol. 60, 1119-1122
5. Ferri, C. P., Prince, M., Brayne, C., Brodaty, H., Fratiglioni, L., Ganguli, M., Hall, K., Hasegawa, K., Hendrie, H., Huang, Y., Jorm, A., Mathers, C., Menezes, P. R., Rimmer, E., and Scazufca, M. (2005) Lancet 366, 2112-2117
6. Lleó, A., Greenberg, S. M., and Growdon, J. H. (2006) Annu. Rev. Med. 57, 513-533
7. Roher, A. E., Chaney, M. O., Kuo, Y.-M., Webster, S. D., Stine, W. B., Haverkamp, L. J., Woods, A. S., Cotter, R. J., Tuohy, J. M., Krafft, G. A., Bonnell, B. S., and Emmerling, M. R. (1996) J. Biol. Chem. 271, 20631-20635
8. Lambert, M. P., Barlow, A. K., Chromy, B. A., Edwards, C., Freed, R., Liosatos, M., Morgan, T. E., Rozovsky, I., Trommer, B., Viola, K. L., Wals, P., Zhang, C., Finch, C. E., Krafft, G. A., and Klein, W. L. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 6448-6453
9. Hartley, D. M., Walsh, D. M., Ye, C. P., Diehl, T., Vasquez, S., Vassilev, P. M., Teplow, D. B., and Selkoe, D. J. (1999) J. Neurosci. 19, 8876-8884
10. Walsh, D. M., Tseng, B. P., Rydel, R. E., Podlisny, M. B., and Selkoe, D. J. (2000) Biochemistry 39, 10831-10839
11. Bitan, G., Lomakin, A., and Teplow, D. B. (2001) J. Biol. Chem. 276, 35176-35184
12. Lashuel, H. A., Hartley, D., Petre, B. M., Walz, T., and Lansbury, P. T., Jr. (2002) Nature 418, 291
13. Hoshi, M., Sato, M., Matsumoto, S., Noguchi, A., Yasutake, K., Yoshida, N., and Sato, K. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 6370-6375
14. Barghorn, S., Nimmrich, V., Striebinger, A., Krantz, C., Keller, P., Janson, B., Bahr, M., Schmidt, M., Bitner, R. S., Harlan, J., Barlow, E., Ebert, U., and Hillen, H. (2005) J. Neurochem. 95, 834-847
15. Lesné, S., MT, K., Kotilinek, L., Kayed, R., Glabe, C. G., Yang, A., Gallagher, M., and Ashe, K. H. (2006) Nature 440, 352-357
16. Hsia, A., Masliah, E., McConlogue, L., Yu, G., Tatsuno, G., Hu, K., Kholodenko, D., Malenka, R. C., Nicoll, R. A., and Mucke, L. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 3228-3233
17. Holcomb, L. A., Gordon, M. N., Jantzen, P., Hsiao, K., Duff, K., and Morgan, D. (1999) Behav. Genet. 29, 177-185
18. Mucke, L., Masliah, E., Yu, G.-Q., Mallory, M., Rockenstein, E. M., Tatsuno, G., Hu, K., Kholodenko, D., Johnson-Wood, K., and McConlogue, L. (2000) J. Neurosci. 20, 4050-4058
19. Westerman, M. A., Cooper-Blacketer, D., Mariash, A., Kotilinek, L., Kawarabayashi, T., Younkin, L. H., Carlson, G. A., Younkin, S. G., and Ashe, K. H. (2002) J. Neurosci. 22, 1858-1867
20. Palop, J. J., Jones, B., Kekonius, L., Chin, J., Yu, G.-Q., Raber, J., Masliah, E., and Mucke, L. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 9572-9577
21. Cummings, B. J., Pike, C. J., Shankle, R., and Cotman, C. W. (1996) Neurobiol. Aging 17, 921-933
22. Knowles, R. B., Gomez-Isla, T., and Hyman, B. T. (1998) J. Neuropathol. Exp. Neurol. 57, 1122-1130
23. Tsai, J., Grutzendler, J., Duff, K., and Gan, W. B. (2004) Nat. Neurosci. 7, 1181-1183
24. Stern, E. A., Bacskai, B. J., Hickey, G. A., Attenello, F. J., Lombardo, J. A., and Hyman, B. T. (2004) J. Neurosci. 24, 4535-4540
25. Younkin, S. G. (1995) Ann. Neurol. 37, 287-288
26. Snyder, S. W., Ladror, U. S., Wade, W. S., Wang, G. T., Barrett, L. W., Matayoshi, E. D., Huffaker, H. J., Kraft, G. A., and Holzman, T. F. (1994) Biophys. J. 67, 1216-1228
27. Kim, J., Onstead, L., Randle, S., Price, R., Smithson, L., Zwizinski, C., Dickson, D. W., Golde, T., and McGowan, E. (2007) J. Neurosci. 27, 627-633
28. Chiti, F., Stefani, M., Taddei, N., Ramponi, G., and Dobson, C. M. (2003) Nature 424, 805-808
29. Nilsberth, C., Westlind-Danielsson, A., Eckman, C. B., Condron, M. M., Axelman, K., Forsell, C., Stenh, C., Luthman, J., Teplow, D. B., Younkin, S. G., Naslund, J., and Lannfelt, L. (2001) Nat. Neurosci. 4, 887-893
30. Lashuel, H. A., Hartley, D. M., Petre, B. M., Wall, J. S., Simon, M. N., Walz, T., Lansbury, J., and Peter, T. (2003) J. Mol. Biol. 332, 795-808
31. Murakami, K., Irie, K., Morimoto, A., Ohigashi, H., Shindo, M., Nagao, M., Shimizu, T., and Shirasawa, T. (2003) J. Biol. Chem. 278, 46179-46187
32. Johansson, A.-S., Berglind-Dehlin, F., Karlsson, G., Edwards, K., Gellerfors, P., and Lannfelt, L. (2006) FEBS J. 273, 2618-2630
33. Hori, Y., Hashimoto, T., Wakutani, Y., Urakami, K., Nakashima, K., Condron, M. M., Tsubuki, S., Saido, T. C., Teplow, D. B., and Iwatsubo, T. (2006) J. Biol. Chem. 282, 4916-4923
34. Cheng, I., Palop, J., Esposito, L., Bien-Ly, N., Yan, F., and Mucke, L. (2004) Nat. Med. 10, 1190-1192
35. Legleiter, J., Czilli, D. L., Gitter, B., DeMattos, R. B., Holtzman, D. M., and Kowalewski, T. (2004) J. Mol. Biol. 335, 997-1006
36. Legleiter, J., DeMattos, R. B., Holtzman, D. M., and Kowalewski, T. (2004) J. Colloid Interface Sci. 278, 96-106
37. Kobayashi, D. T., and Chen, K. S. (2005) Genes Brain and Behav. 4, 173-196
38. Chin, J., Palop, J. J., Puoliväli, J., Massaro, C., Bien-Ly, N., Gerstein, H., Scearce-Levie, K., Masliah, E., and Mucke, L. (2005) J. Neurosci. 25, 9694-9703
39. Esposito, L., Raber, J., Kekonius, L., Fan, Y., Yu, G.-Q., Bien-Ly, N., Puoliväli, J., Scearce-Levie, K., Masliah, E., and Mucke, L. (2006) J. Neurosci. 26, 5167-5179
40. Belzung, C., and Griebel, G. (2001) Behav. Brain Res. 125, 141-149
41. Steward, O., Loesche, J., and Horton, W. C. (1977) Brain Res. Bull. 2, 41-48
42. Hsiao, K. K., Borchelt, D. R., Olson, K., Johannsdottir, R., Kitt, C., Yunis, W., Xu, S., Eckman, C., Younkin, S., Price, D., Iadecola, C., Clark, H. B., and Carlson, G. (1995) Neuron 15, 1203-1218
43. Chin, J., Palop, J. J., Yu, G.-Q., Kojima, N., Masliah, E., and Mucke, L. (2004) J. Neurosci. 24, 4692-4697
44. Palop, J. J., Chin, J., Bien-Ly, N., Massaro, C., Yeung, B. Z., Yu, G.-Q., and Mucke, L. (2005) J. Neurosci. 25, 9686-9693
45. Kowalewski, T., and Holtzman, D. M. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 3688-3693
46. Whalen, B. M., Selkoe, D. J., and Hartley, D. M. (2005) Neurobiol. Dis. 20, 254-266
47. Holcomb, L., Gordon, M. N., McGowan, E., Yu, X., Benkovic, S., Jantzen, P., Wright, K., Saad, I., Mueller, R., Morgan, D., Sanders, S., Zehr, C., O'Campo, K., Hardy, J., Prada, C. M., Eckman, C., Younkin, S., Hsiao, K., and Duff, K. (1998) Nat. Med. 4, 97-100
48. Klein, W. L., Krafft, G. A., and Finch, C. E. (2001) Trends Neurosci. 24, 219-224
49. Deleted in proof.
50. Deleted in proof.
51. Deleted in proof.
52. Deleted in proof.
53. Deleted in proof.
54. Deleted in proof.
55. Deleted in proof.
56. Rockenstein, E., Mante, M., Alford, M., Adame, A., Crews, L., Hashimoto, M., Esposito, L., Mucke, L., and Masliah, E. (2005) J. Biol. Chem. 280, 32957-32967
57. Kerr, M. L., and Small, D. H. (2005) J. Neurosci. Res. 80, 151-159
58. Galvan, V., Gorostiza, O. F., Banwait, S., Ataie, M., Logvinova, A. V., Sitaraman, S., Carlson, E., Sagi, S. A., Chevallier, N., Jin, K., Greenberg, D. A., and Bredesen, D. E. (2006) Proc. Natl. Acad. Sci. U. S. A. 103, 7130-7135
59. Zheng, H., and Koo, E. H. (2006) Mol. Neurodegener. 1, 5
60. Lee, K. W., Im, J. Y., Song, J. S., Lee, S. H., Lee, H. J., Ha, H. Y., Koh, J. Y., Gwag, B. J., Yang, S. D., Paik, S. G., and Han, P. L. (2006) Neurobiol. Dis. 22, 10-24
61. Neve, R. L., and McPhie, D. L. (2007) Biochim. Biophys. Acta 1772, 430-437
62. Dahlgren, K. N., Manelli, A. M., Stine, W. B., Jr., Baker, L. K., Krafft, G. A., and LaDu, M. J. (2002) J. Biol. Chem. 277, 32046-32053
63. Harper, J. D., and Lansbury, P. T. J. (1997) Annu. Rev. Biochem. 66, 385-407
64. Yang, D. S., Yip, C. M., Huang, T. H. J., Chakrabartty, A., and Fraser, P. E. (1999) J. Biol. Chem. 274, 32970-32974
65. Burdick, D., Soreghan, B., Kwon, M., Kosmoski, J., Knauer, M., Henschen, A., Yates, J., Cotman, C., and Glabe, C. (1992) J. Biol. Chem. 267, 546-554
66. Klyubin, I., Walsh, D. M., Cullen, W. K., Fadeeva, J. V., Anwyl, R., Selkoe, D. J., and Rowan, M. J. (2004) Eur. J. Neurosci. 19, 2839-2846
67. Rockenstein, E. M., McConlogue, L., Tan, H., Gordon, M., Power, M., Masliah, E., and Mucke, L. (1995) J. Biol. Chem. 270, 28257-28267
68. Ji, Z. S., Mullendorff, K., Cheng, I. H., Miranda, R. D., Huang, Y., and Mahley, R. W. (2006) J. Biol. Chem. 281, 2683-2692
69. Wang, Q., Walsh, D. M., Rowan, M. J., Selkoe, D. J., and Anwyl, R. (2004) J. Neurosci. 24, 3370-3378
70. Klunk, W. E., Engler, H., Nordberg, A., Wang, Y., Blomqvist, G., Holt, D. P., Bergstrom, M., Savitcheva, I., Huang, G. F., Estrada, S., Ausen, B., Debnath, M. L., Barletta, J., Price, J. C., Sandell, J., Lopresti, B. J., Wall, A., Koivisto, P., Antoni, G., Mathis, C. A., and Langstrom, B. (2004) Ann. Neurol. 55, 306-319
71. Buckner, R. L., Snyder, A. Z., Shannon, B. J., LaRossa, G., Sachs, R., Fotenos, A. F., Sheline, Y. I., Klunk, W. E., Mathis, C. A., Morris, J. C., and Mintun, M. A. (2005) J. Neurosci. 25, 7709-7717
72. Mucke, L., Yu, G.-Q., McConlogue, L., Rockenstein, E. M., Abraham, C. R., and Masliah, E. (2000) Am. J. Pathol. 157, 2003-2010
73. Wyss-Coray, T., Lin, C., Yan, F., Yu, G.-Q., Rohde, M., McConlogue, L., Masliah, E., and Mucke, L. (2001) Nat. Med. 7, 612-618
74. Cherny, R. A., Atwood, C. S., Xilinas, M. E., Gray, D. N., Jones, W. D., McLean, C. A., Barnham, K. J., Volitakis, I., Fraser, F. W., Kim, Y. S., Huang, X. D., Goldstein, L. E., Moir, R. D., Lim, J. T., Beyreuther, K., Zheng, H., Tanzi, R. E., Masters, C. L., and Bush, A. I. (2001) Neuron 30, 665-676
75. Fagan, A. M., Watson, M., Parsadanian, M., Bales, K. R., Paul, S. M., and Holtzman, D. M. (2002) Neurobiol. Dis. 9, 305-318
76. DeMattos, R. B., Cirrito, J. R., Parsadanian, M., May, P. C., O'Dell, M. A., Taylor, J. W., Harmony, J. A. K., Aronow, B. J., Bales, K. R., Paul, S. M., and Holtzman, D. M. (2004) Neuron 41, 193-202