The art of CHO cell engineering: A comprehensive retrospect and future perspectives

Biotechnology Advances

Volumn 33, Issue 8, 2015, Pages 1878-1896

  Fischer, Simon ^a,b   Handrick, René ^a   Otte, Kerstin ^a  

^a BIBERACH UNIVERSITY OF APPLIED SCIENCES   (Germany)

^b UNIVERSITY OF ULM   (Germany)

Author keywords

Biopharmaceuticals; Cell engineering; Chinese hamster ovary (CHO); CRISPR; Gene knockout; Genome editing; MicroRNA; SiRNA; TALEN; ZFN

Indexed keywords

CELL CULTURE; MAMMALS; MANUFACTURE; MOLECULES; RECOMBINANT PROTEINS; TRANSCRIPTION; CELLS; CYTOLOGY; GENES; MULTIOBJECTIVE OPTIMIZATION; PRODUCTION PLATFORMS;

BIOPHARMACEUTICALS; CHINESE HAMSTER OVARY; CRISPR; GENE KNOCKOUT; MICRORNAS; SIRNA; TALEN;

CELL ENGINEERING;

BACTERIA (MICROORGANISMS); CRICETULUS GRISEUS; MAMMALIA;

BACTERIUM; CELLS AND CELL COMPONENTS; DRUG; FUTURE PROSPECT; GENE EXPRESSION; GENETIC ENGINEERING; HOST; MAMMAL; MANUFACTURING; PROTEIN; RECOMBINATION; YEAST;

RECOMBINANT PROTEIN;

ANIMAL; BIOSYNTHESIS; CELL ENGINEERING; CHO CELL LINE; CRICETULUS; CYTOLOGY; GENETICS; HAMSTER; HUMAN; METABOLISM; PROTEIN PROCESSING; TRENDS;

ANIMALS; CELL ENGINEERING; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS;

EID: 84949032232     PISSN: 07349750     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biotechadv.2015.10.015     Document Type: Review

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