Translatome analysis of CHO cells to identify key growth genes

Journal of Biotechnology

Volumn 167, Issue 3, 2013, Pages 215-224

  Courtes, Franck C ^a,b   Lin, Joyce ^a   Lim, Hsueh Lee ^a   Ng, Sze Wai ^a   Wong, Niki S C ^a,c   Koh, Geoffrey ^a   Vardy, Leah ^d   Yap, Miranda G S ^a,b   Loo, Bernard ^a   Lee, Dong Yup ^a,b  

^a AGENCY FOR SCIENCE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c ABBVIE INC   (United States)

^d INSTITUTE OF MEDICAL BIOLOGY   (Singapore)

Author keywords

Cellular growth; CHO cells; Polysome profiling; Translatome

Indexed keywords

CELLULAR GROWTH; CHO CELL; EXPONENTIAL GROWTH PHASE; GLUCOSE-6-PHOSPHATE DEHYDROGENASE; MONOCLONAL ANTIBODIES (MAB); POLYSOME PROFILING; TRANSLATIONAL EFFICIENCIES; TRANSLATOME;

CELL CULTURE; GENE EXPRESSION; LOADING; MONOCLONAL ANTIBODIES; PROTEINS;

TRANSLATION (LANGUAGES);

AMINOPEPTIDASE B; AMYLOID BETA PRECURSOR PROTEIN; ANNEXIN A11; CALPAIN 2; CATHEPSIN L; COPPER ION; CYCLINE; EXOCYST COMPLEX COMPONENT 1; FIP1 LIKE 1 PROTEIN; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; HELICASE LIKE TRANSCRIPTION FACTOR; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A2; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN C; IMPORTIN 8; LEGUMAIN; MAMMALIAN TARGET OF RAPAMYCIN; MINICHROMOSOME MAINTENANCE DEFICIENT 5; PROGRAMMED CELL DEATH 6 INTERACTING PROTEIN; PROTEIN; PROTEIN REGULATOR OF CYTOKINESIS 1; REGULATOR PROTEIN; RUVB LIKE PROTEIN 1; SORTING NEXIN 14; TRANSCRIPTOME; TRYPTOPHAN TRANSFER RNA LIGASE; UNCLASSIFIED DRUG; UNINDEXED DRUG; UTP6 SMALL SUBUNIT PROCESSOME; VACUOLAR PROTEIN SORTING 4B; VALOSIN CONTAINING PROTEIN; MESSENGER RNA;

AMINOACYLATION; ARTICLE; CATABOLISM; CELL CYCLE; CELL GROWTH; CHO CELL; CONTROLLED STUDY; GENE EXPRESSION; GENETIC PARAMETERS; GROWTH CURVE; HOMEOSTASIS; MICROARRAY ANALYSIS; NONHUMAN; POLYSOME; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN TRANSPORT; RIBOSOME; RNA PROCESSING; TRANSLATOME; ANIMAL; BIOLOGY; CHO CELL LINE; CRICETULUS; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENETICS; HAMSTER; METABOLISM; PROCEDURES; PROTEIN SYNTHESIS;

ANIMALS; CHO CELLS; COMPUTATIONAL BIOLOGY; CRICETINAE; CRICETULUS; GENE EXPRESSION PROFILING; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN BIOSYNTHESIS; PROTEINS; RNA, MESSENGER; TRANSCRIPTOME;

EID: 84881496104     PISSN: 01681656     EISSN: 18734863     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2013.07.010     Document Type: Article

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