Overexpression of GADD34 Enhances Production of Recombinant Human Antithrombin III in Chinese Hamster Ovary Cells

Journal of Bioscience and Bioengineering

Volumn 106, Issue 6, 2008, Pages 568-573

  Omasa, Takeshi ^a   Takami, Takashi ^a   Ohya, Tomoshi ^b   Kiyama, Eriko ^a   Hayashi, Tetsuji ^a   Nishii, Hiroko ^b   Miki, Hideo ^b   Kobayashi, Kaoru ^b   Honda, Kohsuke ^a   Ohtake, Hisao ^a  

^a OSAKA UNIVERSITY   (Japan)

^b MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

antithrombin III; Chinese hamster ovary cells; GADD34

Indexed keywords

ANTITHROMBIN III; CHINESE HAMSTER OVARIES; CHINESE HAMSTER OVARY CELLS; CHO CELLS; CULTURE SUPERNATANT; DNA DAMAGES; FUCOSYLATION; GADD34; GROWTH ARRESTS; OVEREXPRESSION; RECOMBINANT HUMAN ANTITHROMBIN; SECRETED PROTEINS; SPECIFIC ACTIVITIES; UNFOLDED PROTEIN RESPONSES;

CLONING; DRUG PRODUCTS; GENE ENCODING; MEATS; NUCLEIC ACIDS; ORGANIC ACIDS; TRANSCRIPTION; TRANSCRIPTION FACTORS;

CELL CULTURE;

ANIMALS; ANTIGENS, DIFFERENTIATION; ANTITHROMBIN III; BASE SEQUENCE; BLOTTING, WESTERN; CELL CYCLE PROTEINS; CHO CELLS; CRICETINAE; CRICETULUS; DNA PRIMERS; HUMANS; RECOMBINANT PROTEINS;

CRICETULUS GRISEUS;

EID: 58149136228     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1263/jbb.106.568     Document Type: Article

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