메뉴 건너뛰기




Volumn 10, Issue 3, 2004, Pages 544-550

Sequence-specific inhibition of microRNA-and siRNA-induced RNA silencing

Author keywords

miRNA; miRNP; mRNA degradation; Posttranscriptional gene regulation; RNA interference; Translational regulation

Indexed keywords

2' DEOXYOLIGONUCLEOTIDE DERIVATIVE; 2' O METHYL OLIGORIBONUCLEOTIDE DERIVATIVE; CELL EXTRACT; MICRORNA; OLIGONUCLEOTIDE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 1242318826     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1261/rna.5235104     Document Type: Article
Times cited : (542)

References (75)
  • 1
    • 0038708326 scopus 로고    scopus 로고
    • The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs
    • Abrahante, J.E., Daul, A.L., Li, M., Volk, M.L., Tennessen, J.M., Miller, E.A., and Rougvie, A.E. 2003. The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs. Dev. Cell 4: 625-637.
    • (2003) Dev. Cell , vol.4 , pp. 625-637
    • Abrahante, J.E.1    Daul, A.L.2    Li, M.3    Volk, M.L.4    Tennessen, J.M.5    Miller, E.A.6    Rougvie, A.E.7
  • 2
    • 0038343499 scopus 로고    scopus 로고
    • MicroRNA pathways in flies and worms: Growth, death, fat, stress, and timing
    • Ambros, V. 2003. MicroRNA pathways in flies and worms: Growth, death, fat, stress, and timing. Cell 113: 673-676.
    • (2003) Cell , vol.113 , pp. 673-676
    • Ambros, V.1
  • 5
    • 0242361521 scopus 로고    scopus 로고
    • Regulation of flowering time and floral organ identity by a microRNA and its APETALA2-like target genes
    • Aukerman, M.J. and Sakai, H. 2003. Regulation of flowering time and floral organ identity by a microRNA and its APETALA2-like target genes. Plant Cell 15: 2730-2741.
    • (2003) Plant Cell , vol.15 , pp. 2730-2741
    • Aukerman, M.J.1    Sakai, H.2
  • 6
    • 0345064195 scopus 로고    scopus 로고
    • Developmental defects by antisense-mediated inactivation of microRNAs 2 and 13 in Drosophila and the identification of putative target genes
    • Boutla, A., Delidakis, C., and Tabler, M. 2003. Developmental defects by antisense-mediated inactivation of microRNAs 2 and 13 in Drosophila and the identification of putative target genes. Nucleic Acids Res. 31: 4973-4980.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 4973-4980
    • Boutla, A.1    Delidakis, C.2    Tabler, M.3
  • 7
    • 0347906099 scopus 로고    scopus 로고
    • Towards a complete description of the microRNA complement of animal genomes
    • Brennecke, J. and Cohen, S.M. 2003. Towards a complete description of the microRNA complement of animal genomes. Genome Biol. 4: 228.
    • (2003) Genome Biol. , vol.4 , pp. 228
    • Brennecke, J.1    Cohen, S.M.2
  • 8
    • 0037418839 scopus 로고    scopus 로고
    • bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila
    • Brennecke, J., Hipfner, D.R., Stark, A., Russell, R.B., and Cohen, S.M. 2003. bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. Cell 113: 25-36.
    • (2003) Cell , vol.113 , pp. 25-36
    • Brennecke, J.1    Hipfner, D.R.2    Stark, A.3    Russell, R.B.4    Cohen, S.M.5
  • 10
    • 0038299558 scopus 로고    scopus 로고
    • Role of microRNAs in plant and animal development
    • Carrington, J.C. and Ambros, V. 2003. Role of microRNAs in plant and animal development. Science 301: 336-338.
    • (2003) Science , vol.301 , pp. 336-338
    • Carrington, J.C.1    Ambros, V.2
  • 11
    • 0036792769 scopus 로고    scopus 로고
    • Fragile X-related protein and V1G associate with the RNA interference machinery
    • Caudy, A.A., Myers, M., Hannon, G.J., and Hammond, S.M. 2002. Fragile X-related protein and V1G associate with the RNA interference machinery. Genes & Dev. 16: 2491-2496.
    • (2002) Genes & Dev. , vol.16 , pp. 2491-2496
    • Caudy, A.A.1    Myers, M.2    Hannon, G.J.3    Hammond, S.M.4
  • 12
    • 0141865485 scopus 로고    scopus 로고
    • A microRNA as a translational repressor of APETALA2 in Arabidopsis flower development
    • Chen, X. 2003. A microRNA as a translational repressor of APETALA2 in Arabidopsis flower development. Science 11: 11.
    • (2003) Science , vol.11 , pp. 11
    • Chen, X.1
  • 13
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P. and Sacchi, N. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 14
    • 0029077840 scopus 로고
    • Characterization of fully 2′-modified oligoribonucleotide hetero- and homoduplex hybridization and nuclease sensitivity
    • Cummins, L.L., Owens, S.R., Risen, L.M., Lesnik, E.A., Freier, S.M., McGee, D., Guinosso, C.J., and Cook, P.D. 1995. Characterization of fully 2′-modified oligoribonucleotide hetero- and homoduplex hybridization and nuclease sensitivity. Nucleic Acids Res. 23: 2019-2024.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 2019-2024
    • Cummins, L.L.1    Owens, S.R.2    Risen, L.M.3    Lesnik, E.A.4    Freier, S.M.5    McGee, D.6    Guinosso, C.J.7    Cook, P.D.8
  • 15
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam, J.D., Lebovitz, R.M., and Roeder, R.G. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11: 1475-1489.
    • (1983) Nucleic Acids Res. , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 17
    • 0037320941 scopus 로고    scopus 로고
    • Numerous microRNPs in neuronal cells containing novel microRNAs
    • Dostie, J., Mourelatos, Z., Yang, M., Sharma, A., and Dreyfuss, G. 2003. Numerous microRNPs in neuronal cells containing novel microRNAs. RNA 9: 180-186.
    • (2003) RNA , vol.9 , pp. 180-186
    • Dostie, J.1    Mourelatos, Z.2    Yang, M.3    Sharma, A.4    Dreyfuss, G.5
  • 18
    • 0037686295 scopus 로고    scopus 로고
    • Killing the messenger: Short RNAs that silence gene expression
    • Dykxhoorn, D.M., Novina, C.D., and Sharp, P.A. 2003. Killing the messenger: Short RNAs that silence gene expression. Nat. Rev. Mol. Cell Biol. 4: 457-467.
    • (2003) Nat. Rev. Mol. Cell Biol. , vol.4 , pp. 457-467
    • Dykxhoorn, D.M.1    Novina, C.D.2    Sharp, P.A.3
  • 19
    • 0035803583 scopus 로고    scopus 로고
    • Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
    • Elbashir, S.M., Martinez, J., Patkaniowska, A., Lendeckel, W., and Tuschl, T. 2001. Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J. 20: 6877-6888.
    • (2001) EMBO J. , vol.20 , pp. 6877-6888
    • Elbashir, S.M.1    Martinez, J.2    Patkaniowska, A.3    Lendeckel, W.4    Tuschl, T.5
  • 20
    • 0036351317 scopus 로고    scopus 로고
    • Analysis of gene function in somatic mammalian cells using small interfering RNAs
    • Elbashir, S.M., Harborth, J., Weber, K., and Tuschl, T. 2002. Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods 26: 199-213.
    • (2002) Methods , vol.26 , pp. 199-213
    • Elbashir, S.M.1    Harborth, J.2    Weber, K.3    Tuschl, T.4
  • 24
    • 0042528729 scopus 로고    scopus 로고
    • Heterochromatin and epigenetic control of gene expression
    • Grewal, S.I. and Moazed, D. 2003. Heterochromatin and epigenetic control of gene expression. Science 301: 798-802.
    • (2003) Science , vol.301 , pp. 798-802
    • Grewal, S.I.1    Moazed, D.2
  • 25
    • 17844364875 scopus 로고    scopus 로고
    • Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
    • Grishok, A., Pasquinelli, A.E., Conte, D., Li, N., Parrish, S., Ha, I., Baillie, D.L., Fire, A., Ruvkun, G., and Mello, C.C. 2001. Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106: 23-34.
    • (2001) Cell , vol.106 , pp. 23-34
    • Grishok, A.1    Pasquinelli, A.E.2    Conte, D.3    Li, N.4    Parrish, S.5    Ha, I.6    Baillie, D.L.7    Fire, A.8    Ruvkun, G.9    Mello, C.C.10
  • 26
    • 0242318333 scopus 로고    scopus 로고
    • MicroRNAs: A role in plant development
    • Hake, S. 2003. MicroRNAs: A role in plant development. Curr. Biol. 13: R851-R852.
    • (2003) Curr. Biol. , vol.13
    • Hake, S.1
  • 27
    • 0042442335 scopus 로고    scopus 로고
    • Embryonic stem cell-specific MicroRNAs
    • Houbaviy, H.B., Murray, M.F., and Sharp, P.A. 2003. Embryonic stem cell-specific MicroRNAs. Dev. Cell 5: 351-358.
    • (2003) Dev. Cell , vol.5 , pp. 351-358
    • Houbaviy, H.B.1    Murray, M.F.2    Sharp, P.A.3
  • 28
    • 0037144546 scopus 로고    scopus 로고
    • A microRNA in a multiple-turnover RNAi enzyme complex
    • Hutvágner, G. and Zamore, P.D. 2002. A microRNA in a multiple-turnover RNAi enzyme complex. Science 297: 2056-2060.
    • (2002) Science , vol.297 , pp. 2056-2060
    • Hutvágner, G.1    Zamore, P.D.2
  • 29
    • 0035800521 scopus 로고    scopus 로고
    • A cellular function for the RNA interference enzyme Dicer in small temporal RNA maturation
    • Hutvágner, G., McLachlan, I., Bálint, É., Tuschl, T., and Zamore, P.D. 2001. A cellular function for the RNA interference enzyme Dicer in small temporal RNA maturation. Science 93: 834-838.
    • (2001) Science , vol.93 , pp. 834-838
    • Hutvágner, G.1    McLachlan, I.2    Bálint, É.3    Tuschl, T.4    Zamore, P.D.5
  • 31
    • 0035887005 scopus 로고    scopus 로고
    • Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
    • Ketting, R.F., Fischer, S.E., Bernstein, E., Sijen, T., Hannon, G.J., and Plasterk, R.H. 2001. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes & Dev. 15: 2654-2659.
    • (2001) Genes & Dev. , vol.15 , pp. 2654-2659
    • Ketting, R.F.1    Fischer, S.E.2    Bernstein, E.3    Sijen, T.4    Hannon, G.J.5    Plasterk, R.H.6
  • 32
    • 0141631876 scopus 로고    scopus 로고
    • A microRNA array reveals extensive regulation of microRNAs during brain development
    • Krichevsky, A.M., King, K.S., Donahue, C.P., Khrapko, K., and Kosik, K.S. 2003. A microRNA array reveals extensive regulation of microRNAs during brain development. RNA 9: 1274-1281.
    • (2003) RNA , vol.9 , pp. 1274-1281
    • Krichevsky, A.M.1    King, K.S.2    Donahue, C.P.3    Khrapko, K.4    Kosik, K.S.5
  • 33
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • Lagos-Quintana, M., Rauhut, R., Lendeckel, W., and Tuschl, T. 2001. Identification of novel genes coding for small expressed RNAs. Science 294: 853-858.
    • (2001) Science , vol.294 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 37
    • 0027254030 scopus 로고
    • Antisense oligonucleotides made of 2′-O-alkylRNA: Their properties and applications in RNA biochemistry
    • Lamond, A.I. and Sproat, B.S. 1993. Antisense oligonucleotides made of 2′-O-alkylRNA: Their properties and applications in RNA biochemistry. FEBS Lett. 325: 123-127.
    • (1993) FEBS Lett. , vol.325 , pp. 123-127
    • Lamond, A.I.1    Sproat, B.S.2
  • 38
    • 0035955361 scopus 로고    scopus 로고
    • An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    • Lau, N.C., Lim, L.P., Weinstein, E.G., and Bartel, D.P. 2001. An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294: 858-862.
    • (2001) Science , vol.294 , pp. 858-862
    • Lau, N.C.1    Lim, L.P.2    Weinstein, E.G.3    Bartel, D.P.4
  • 39
    • 0035955366 scopus 로고    scopus 로고
    • An extensive class of small RNAs in Caenorhabditis elegans
    • Lee, R.C. and Ambros, V. 2001. An extensive class of small RNAs in Caenorhabditis elegans. Science 294: 862-864.
    • (2001) Science , vol.294 , pp. 862-864
    • Lee, R.C.1    Ambros, V.2
  • 40
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee, R.C., Feinbaum, R.L., and Ambros, V. 1993. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin- 14. Cell 75: 843-854.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 41
    • 0037009364 scopus 로고    scopus 로고
    • MicroRNA maturation: Stepwise processing and subcellular localization
    • Lee, Y., Jeon, K., Lee, J.T., Kim, S., and Kim, V.N. 2002. MicroRNA maturation: Stepwise processing and subcellular localization. EMBO J. 21: 4663-4670.
    • (2002) EMBO J. , vol.21 , pp. 4663-4670
    • Lee, Y.1    Jeon, K.2    Lee, J.T.3    Kim, S.4    Kim, V.N.5
  • 46
    • 0035984059 scopus 로고    scopus 로고
    • Endogenous and silencing-associated small RNAs in plants
    • Llave, C., Kasschau, K.D., Rector, M.A., and Carrington, J.C. 2002a. Endogenous and silencing-associated small RNAs in plants. Plant Cell 14: 1605-1619.
    • (2002) Plant Cell , vol.14 , pp. 1605-1619
    • Llave, C.1    Kasschau, K.D.2    Rector, M.A.3    Carrington, J.C.4
  • 47
    • 0037144457 scopus 로고    scopus 로고
    • Cleavage of Scarecrow-like mRNA targets directed by a class of Arabidopsis miRNA
    • Llave, C., Xie, Z., Kasschau, K.D., and Carrington, J.C. 2002b. Cleavage of Scarecrow-like mRNA targets directed by a class of Arabidopsis miRNA. Science 297: 2053-2056.
    • (2002) Science , vol.297 , pp. 2053-2056
    • Llave, C.1    Xie, Z.2    Kasschau, K.D.3    Carrington, J.C.4
  • 48
    • 0032077477 scopus 로고    scopus 로고
    • Advantages of 2′-O-methyl oligoribonucleotide probes for detecting RNA targets
    • Majlessi, M., Nelson, N.C., and Becker, M.M. 1998. Advantages of 2′-O-methyl oligoribonucleotide probes for detecting RNA targets. Nucleic Acids Res. 26: 2224-2229.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 2224-2229
    • Majlessi, M.1    Nelson, N.C.2    Becker, M.M.3
  • 49
    • 0037031576 scopus 로고    scopus 로고
    • Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
    • Martinez, J., Patkaniowska, A., Urlaub, H., Lührmann, R., and Tuschl, T. 2002. Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 110: 563-574.
    • (2002) Cell , vol.110 , pp. 563-574
    • Martinez, J.1    Patkaniowska, A.2    Urlaub, H.3    Lührmann, R.4    Tuschl, T.5
  • 50
    • 0036738077 scopus 로고    scopus 로고
    • Short RNAs can identify new candidate transposable element families in Arabidopsis
    • Mette, M.F., van der Winden, J., Matzke, M., and Matzke, A.J. 2002. Short RNAs can identify new candidate transposable element families in Arabidopsis. Plant Physiol. 130: 6-9.
    • (2002) Plant Physiol. , vol.130 , pp. 6-9
    • Mette, M.F.1    Van Der Winden, J.2    Matzke, M.3    Matzke, A.J.4
  • 52
    • 0030970775 scopus 로고    scopus 로고
    • The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA
    • Moss, E.G., Lee, R.C., and Ambros, V. 1997. The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA. Cell 88: 637-646.
    • (1997) Cell , vol.88 , pp. 637-646
    • Moss, E.G.1    Lee, R.C.2    Ambros, V.3
  • 54
    • 0033572284 scopus 로고    scopus 로고
    • The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation
    • Olsen, P.H. and Ambros, V. 1999. The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation. Dev. Biol. 216: 671-680.
    • (1999) Dev. Biol. , vol.216 , pp. 671-680
    • Olsen, P.H.1    Ambros, V.2
  • 56
    • 0037015239 scopus 로고    scopus 로고
    • CARPEL FACTORY, a Dicer homolog, and HEN1, a novel protein, act in microRNA metabolism in Arabidopsis thaliana
    • Park, W., Li, J., Song, R., Messing, J., and Chen, X. 2002. CARPEL FACTORY, a Dicer homolog, and HEN1, a novel protein, act in microRNA metabolism in Arabidopsis thaliana. Curr. Biol. 12: 1484-1495.
    • (2002) Curr. Biol. , vol.12 , pp. 1484-1495
    • Park, W.1    Li, J.2    Song, R.3    Messing, J.4    Chen, X.5
  • 57
    • 0036437372 scopus 로고    scopus 로고
    • Control and developmental timing by microRNAs and their targets
    • Pasquinelli, A.E. and Ruvkun, G. 2002. Control and developmental timing by microRNAs and their targets. Annu. Rev. Cell Dev. Biol. 18: 495-513.
    • (2002) Annu. Rev. Cell Dev. Biol. , vol.18 , pp. 495-513
    • Pasquinelli, A.E.1    Ruvkun, G.2
  • 58
    • 0041506564 scopus 로고    scopus 로고
    • Cloning of small RNA molecules
    • (eds. F.M. Ausubel et al.). John Wiley and Sons, New York
    • Pfeffer, S., Lagos-Quintana, M., and Tuschl, T. 2003. Cloning of small RNA molecules. In: Current protocols in molecular biology (eds. F.M. Ausubel et al.), pp. 26.24.21-26.24.16. John Wiley and Sons, New York.
    • (2003) Current Protocols in Molecular Biology , pp. 262421-262416
    • Pfeffer, S.1    Lagos-Quintana, M.2    Tuschl, T.3
  • 63
    • 0142173075 scopus 로고    scopus 로고
    • Small RNAs with imperfect match to endogenous mRNA repress translation: Implications for off-target activity of siRNA in mammalian cells
    • Saxena, S., Jonsson, Z.O., and Dutta, A. 2003. Small RNAs with imperfect match to endogenous mRNA repress translation: implications for off-target activity of siRNA in mammalian cells. J. Biol. Chem. 278: 44312-44319.
    • (2003) J. Biol. Chem. , vol.278 , pp. 44312-44319
    • Saxena, S.1    Jonsson, Z.O.2    Dutta, A.3
  • 64
    • 0034048553 scopus 로고    scopus 로고
    • Advanced 5′-silyl-2′-orthoester approach to RNA oligonucleotide synthesis
    • Scaringe, S.A. 2001a. Advanced 5′-silyl-2′-orthoester approach to RNA oligonucleotide synthesis. Methods Enzymol. 317: 3-18.
    • (2001) Methods Enzymol. , vol.317 , pp. 3-18
    • Scaringe, S.A.1
  • 65
    • 0034840624 scopus 로고    scopus 로고
    • RNA oligonucleotide synthesis via 5′-silyl-2′-orthoester chemistry
    • -. 2001b. RNA oligonucleotide synthesis via 5′-silyl-2′ -orthoester chemistry. Methods 23: 206-217.
    • (2001) Methods , vol.23 , pp. 206-217
  • 66
    • 0037085968 scopus 로고    scopus 로고
    • Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation
    • Seggerson, K., Tang, L., and Moss, E.G. 2002. Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation. Dev. Biol. 243: 215-225.
    • (2002) Dev. Biol. , vol.243 , pp. 215-225
    • Seggerson, K.1    Tang, L.2    Moss, E.G.3
  • 67
    • 0031468448 scopus 로고    scopus 로고
    • Temporal pattern formation by heterochronic genes
    • Slack, F. and Ruvkun, G. 1997. Temporal pattern formation by heterochronic genes. Annu. Rev. Genet. 31: 611-634.
    • (1997) Annu. Rev. Genet. , vol.31 , pp. 611-634
    • Slack, F.1    Ruvkun, G.2
  • 68
    • 0033634943 scopus 로고    scopus 로고
    • The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor
    • Slack, F.J., Basson, M., Liu, Z., Ambros, V., Horvitz, H.R., and Ruvkun, G. 2000. The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Mol. Cell 5: 659-669.
    • (2000) Mol. Cell , vol.5 , pp. 659-669
    • Slack, F.J.1    Basson, M.2    Liu, Z.3    Ambros, V.4    Horvitz, H.R.5    Ruvkun, G.6
  • 70
    • 0037224921 scopus 로고    scopus 로고
    • A biochemical framework for RNA silencing in plants
    • Tang, G., Reinhart, B.I., Bartel, D.P., and Zamore, P.D. 2003. A biochemical framework for RNA silencing in plants. Genes & Dev. 17: 49-63.
    • (2003) Genes & Dev. , vol.17 , pp. 49-63
    • Tang, G.1    Reinhart, B.I.2    Bartel, D.P.3    Zamore, P.D.4
  • 71
    • 17344372249 scopus 로고    scopus 로고
    • Modified oligonucleotides: Synthesis and strategy for users
    • Verma, S. and Eckstein, F. 1998. Modified oligonucleotides: Synthesis and strategy for users. Annu. Rev. Biochem. 67: 99-134.
    • (1998) Annu. Rev. Biochem. , vol.67 , pp. 99-134
    • Verma, S.1    Eckstein, F.2
  • 72
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
    • Wightman, B., Ha, I., and Ruvkun, G. 1993. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75: 855-862.
    • (1993) Cell , vol.75 , pp. 855-862
    • Wightman, B.1    Ha, I.2    Ruvkun, G.3
  • 73
    • 0037694970 scopus 로고    scopus 로고
    • The Drosophila microRNA mir-14 suppresses cell death and is required for normal fat metabolism
    • Xu, P., Vernooy, S.Y., Guo, M., and Hay, B.A. 2003. The Drosophila microRNA mir-14 suppresses cell death and is required for normal fat metabolism. Curr. Biol. 13: 790-795.
    • (2003) Curr. Biol. , vol.13 , pp. 790-795
    • Xu, P.1    Vernooy, S.Y.2    Guo, M.3    Hay, B.A.4
  • 74
    • 0036294527 scopus 로고    scopus 로고
    • Both natural and designed microRNAs can inhibit the expression of cognate mRNAs when expressed in human cells
    • Zeng, Y., Wagner, E.J., and Cullen, B.R. 2002. Both natural and designed microRNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol. Cell 9: 1327-1333.
    • (2002) Mol. Cell , vol.9 , pp. 1327-1333
    • Zeng, Y.1    Wagner, E.J.2    Cullen, B.R.3
  • 75
    • 0041691111 scopus 로고    scopus 로고
    • MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms
    • Zeng, Y., Yi, R., and Cullen, B.R. 2003. MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms. Proc. Natl. Acad. Sci. 100: 9779-9784.
    • (2003) Proc. Natl. Acad. Sci. , vol.100 , pp. 9779-9784
    • Zeng, Y.1    Yi, R.2    Cullen, B.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.