Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA

Nature

Volumn 408, Issue 6808, 2000, Pages 86-89

  Pasquinelli, Amy E ^a   Reinhart, Brenda J ^a   Slack, Frank ^b   Martindale, Mark Q ^c   Kuroda, Mitzi I ^d   Maller, Betsy ^b   Hayward, David C ^e   Ball, Eldon E ^e   Degnan, Bernard ^f   Müller, Peter ^g   Spring, Jürg ^g   Srinivasan, Ashok ^a   Fishman, Mark ^a   Finnerty, John ^h   Corbo, Joseph ⁱ   Levine, Michael ⁱ   Leahy, Patrick ^j   Davidson, Eric ^j   Ruvkun, Gary ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b YALE UNIVERSITY   (United States)

^c UNIVERSITY OF HAWAII   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^f UNIVERSITY OF QUEENSLAND   (Australia)

^g UNIVERSITY OF BASEL   (Switzerland)

^h Boston University   (United States)

ⁱ UNIVERSITY OF CALIFORNIA   (United States)

^j CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

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Author keywords

[No Author keywords available]

Indexed keywords

RNA;

ARABIDOPSIS; ARTICLE; CAENORHABDITIS ELEGANS; CELL FATE; EMBRYO DEVELOPMENT; ESCHERICHIA COLI; GENE CONTROL; GENE EXPRESSION; GENETIC CONSERVATION; HUMAN; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

NON-PROGRAMMATIC;

ADULT; ANIMALS; BASE SEQUENCE; CAENORHABDITIS ELEGANS; CONSERVED SEQUENCE; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MOLECULAR SEQUENCE DATA; PHYLOGENY; RNA; RNA, HELMINTH; SPECIES SPECIFICITY;

ANIMALIA; ANNELIDA; ARABIDOPSIS; ARTHROPODA; ASCIDIA; CAENORHABDITIS ELEGANS; CNIDARIA; DANIO RERIO; ESCHERICHIA COLI; EUKARYOTA; INVERTEBRATA; MOLLUSCA; SACCHAROMYCES CEREVISIAE; VERTEBRATA;

EID: 0034597777     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35040556     Document Type: Article

References (14)

1. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
2. The 21-nucleotide let-7 RNA regulates developmental timing in C. elegans
3. Mutations that lead to reiterations in the cell lineages of C. elegans
4. The lin-14 locus of Caenorhabditis elegans controls the time of expression of specific postembryonic developmental events
5. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
6. The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor
7. Evidence for a clade of nematodes, arthropods and other moulting animals
8. RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
9. An RNA-directed nuclease mediates posttranscriptional gene silencing in Drosophila cells
10. Targeted mRNA degradation by double-stranded RNA in vitro
11. RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabiditis elegans
12. Potent and specific genetic interference by double-stranded RNA in Caenorhbditis elegans
13. The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation
14. The rde-1 gene, RNA interference, and transposon silencing in C. elegans