CHO microRNA engineering is growing up: Recent successes and future challenges

Biotechnology Advances

Volumn 31, Issue 8, 2013, Pages 1501-1513

  Jadhav, Vaibhav ^a   Hackl, Matthias ^a   Druz, Aliaksandr ^b,c   Shridhar, Smriti ^a   Chung, Cheng Yu ^c   Heffner, Kelley M ^c   Kreil, David P ^a,d   Betenbaugh, Mike ^c   Shiloach, Joseph ^b   Barron, Niall ^e   Grillari, Johannes ^a   Borth, Nicole ^a,f  

^a UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c Johns Hopkins University   (United States)

^d UNIVERSITY OF WARWICK   (United Kingdom)

^e DUBLIN CITY UNIVERSITY   (Ireland)

^f AUSTRIAN CENTRE OF INDUSTRIAL BIOTECHNOLOGY   (Austria)

Author keywords

Bioprocess relevant properties; Chinese Hamster Ovary cells; MicroRNA engineering

Indexed keywords

BIOLOGICAL MODELS; BIOPROCESSES; CELLULAR BEHAVIORS; CHINESE HAMSTER OVARY CELLS; FUTURE CHALLENGES; MICRORNAS; POTENTIAL TARGETS; REGULATORY MECHANISM;

CELL CULTURE; CELL ENGINEERING; CELLS; GENES; MODELS;

RNA;

CELL ORGANELLE; DATA SET; GENETIC ISOLATION; OPTIMIZATION; PHENOTYPE; PHYSIOLOGY; RNA;

CRICETULUS GRISEUS;

MICRORNA; RECOMBINANT PROTEIN;

ANIMAL; BIOPROCESS RELEVANT PROPERTIES; BIOTECHNOLOGY; CELL ENGINEERING; CHINESE HAMSTER OVARY CELLS; CHO CELL LINE; CRICETULUS; HAMSTER; MICRORNA ENGINEERING; REVIEW;

BIOPROCESS RELEVANT PROPERTIES; CHINESE HAMSTER OVARY CELLS; MICRORNA ENGINEERING;

ANIMALS; BIOTECHNOLOGY; CELL ENGINEERING; CHO CELLS; CRICETINAE; CRICETULUS; MICRORNAS; RECOMBINANT PROTEINS;

EID: 84887988404     PISSN: 07349750     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biotechadv.2013.07.007     Document Type: Review

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