Enhanced sialylation of recombinant erythropoietin in genetically engineered Chinese-hamster ovary cells

Biotechnology and Applied Biochemistry

Volumn 52, Issue 4, 2009, Pages 283-291

  Jeong, Yeon Tae ^a   Choi, One ^a   Son, Young Dok ^a   Park, Seung Yeol ^a   Kim, Jung Hoe ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Chinese hamster ovary cells (CHO cells); CMP sialic acid synthase; CMP sialic acid transporter; Erythropoietin; Sialylation; Sialyltransferase

Indexed keywords

CHINESE-HAMSTER OVARY CELLS (CHO CELLS); CMP-SIALIC ACID SYNTHASE; CMP-SIALIC ACID TRANSPORTER; ERYTHROPOIETIN; SIALYLATION; SIALYLTRANSFERASE;

ACIDS; CARBOXYLIC ACIDS; CELL MEMBRANES; CYTOLOGY; ENZYMES; GENETIC ENGINEERING; GLYCOPROTEINS; MEATS; PROTEINS; SETTLING TANKS; SUGAR (SUCROSE); SUGARS; SYNTHETIC APERTURE SONAR;

NANOTECHNOLOGY;

ALPHA 2,3 SIALYLTRANSFERASE; CARRIER PROTEIN; CMP SIALIC ACID SYNTHETASE; CMP SIALIC ACID TRANSPORTER; RECOMBINANT ERYTHROPOIETIN; SIALYLTRANSFERASE; SYNTHETASE; UNCLASSIFIED DRUG; N ACETYLNEURAMINIC ACID;

ANIMAL CELL; ARTICLE; CARBOHYDRATE TRANSPORT; CELL CLONE; CELL GROWTH; CHO CELL; CONTROLLED STUDY; CULTURE MEDIUM; EXPRESSION VECTOR; GENE OVEREXPRESSION; GENETIC ENGINEERING; GLYCOSYLATION; GOLGI COMPLEX; NONHUMAN; NUCLEOTIDE SEQUENCE; NULL CELL; PROTEIN PURIFICATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SIALYLATION; WESTERN BLOTTING; ANIMAL; CRICETULUS; GENETIC ENHANCEMENT; GENETICS; HAMSTER; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; METHODOLOGY; PROTEIN ENGINEERING;

CRICETINAE; CRICETULUS GRISEUS;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; ERYTHROPOIETIN, RECOMBINANT; GENETIC ENHANCEMENT; HUMANS; N-ACETYLNEURAMINIC ACID; PROTEIN ENGINEERING;

EID: 66149104098     PISSN: 08854513     EISSN: None     Source Type: Journal    
DOI: 10.1042/BA20080044     Document Type: Article

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