Cooverexpression of alanine aminotransferase 1 in Chinese hamster ovary cells overexpressing taurine transporter further stimulates metabolism and enhances product yield

Biotechnology and Bioengineering

Volumn 110, Issue 8, 2013, Pages 2208-2215

  Tabuchi, Hisahiro ^a   Sugiyama, Tomoya ^a  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

ALT1; Byproduct alanine; Cell viability; Cooverexpression; TAUT; XBP1

Indexed keywords

ALT1; CELL VIABILITY; COOVEREXPRESSION; TAUT; XBP1;

BATCH CELL CULTURE; CELL ENGINEERING; CELLS; CYTOLOGY; METABOLISM; MONOCLONAL ANTIBODIES; PRODUCTIVITY; STRAIN;

AMINO ACIDS;

ALANINE AMINOTRANSFERASE; ALANINE AMINOTRANSFERASE 1; TAURINE TRANSPORTER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOREACTOR; CELL CLONE; CELL DENSITY; CELL ENGINEERING; CELL GROWTH; CELL METABOLISM; CELL PROLIFERATION; CELL VIABILITY; CHO CELL; FED BATCH CULTURE; FEMALE; GENE OVEREXPRESSION; NONHUMAN; PRODUCTIVITY; PROTEIN EXPRESSION;

ALANINE TRANSAMINASE; ANIMALS; BIOTECHNOLOGY; CELL CULTURE TECHNIQUES; CHO CELLS; CRICETULUS; FEMALE; GENE EXPRESSION; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; RECOMBINANT PROTEINS;

CRICETULUS GRISEUS;

EID: 84879603268     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24881     Document Type: Article

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