메뉴 건너뛰기




Volumn 15, Issue 6, 2008, Pages 581-590

Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster

Author keywords

[No Author keywords available]

Indexed keywords

ARGONAUTE 2 PROTEIN; NUCLEIC ACID; SMALL INTERFERING RNA;

EID: 44349101881     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.1438     Document Type: Article
Times cited : (168)

References (42)
  • 1
    • 33746785696 scopus 로고    scopus 로고
    • Genome-wide in silico identification and analysis of cis natural antisense transcripts (cis-NATs) in ten species
    • Zhang, Y., Liu, X.S., Liu, Q.R. & Wei, L. Genome-wide in silico identification and analysis of cis natural antisense transcripts (cis-NATs) in ten species. Nucleic Acids Res. 34, 3465-3475 (2006).
    • (2006) Nucleic Acids Res , vol.34 , pp. 3465-3475
    • Zhang, Y.1    Liu, X.S.2    Liu, Q.R.3    Wei, L.4
  • 2
    • 24644472515 scopus 로고    scopus 로고
    • Antisense transcription in the mammalian transcriptome
    • Katayama, S. et al. Antisense transcription in the mammalian transcriptome. Science 309, 1564-1566 (2005).
    • (2005) Science , vol.309 , pp. 1564-1566
    • Katayama, S.1
  • 3
    • 12244275645 scopus 로고    scopus 로고
    • Widespread occurrence of antisense transcription in the human genome
    • Yelin, R. et al. Widespread occurrence of antisense transcription in the human genome. Nat. Biotechnol. 21, 379-386 (2003).
    • (2003) Nat. Biotechnol , vol.21 , pp. 379-386
    • Yelin, R.1
  • 4
    • 0030748996 scopus 로고    scopus 로고
    • Making (anti)sense of non-coding sequence conservation
    • Lipman, D.J. Making (anti)sense of non-coding sequence conservation. Nucleic Acids Res. 25, 3580-3583 (1997).
    • (1997) Nucleic Acids Res , vol.25 , pp. 3580-3583
    • Lipman, D.J.1
  • 5
    • 29244490062 scopus 로고    scopus 로고
    • Borsani, O., Zhu, J., Verslues, P.E., Sunkar, R. & Zhu, J.K. Endogenous siRNAs derived from a pair of natural cis-antisense transcripts regulate salt tolerance in Arabidopsis. Cell 123, 1279-1291 (2005).
    • Borsani, O., Zhu, J., Verslues, P.E., Sunkar, R. & Zhu, J.K. Endogenous siRNAs derived from a pair of natural cis-antisense transcripts regulate salt tolerance in Arabidopsis. Cell 123, 1279-1291 (2005).
  • 6
    • 40249088355 scopus 로고    scopus 로고
    • Jin, H., Vacic, V., Girke, T., Lonardi, S. & Zhu, J.K. Small RNAs and the regulation of cis-natural antisense transcripts in Arabidopsis. BMC Mol. Biol. 9, 6 (2008).
    • Jin, H., Vacic, V., Girke, T., Lonardi, S. & Zhu, J.K. Small RNAs and the regulation of cis-natural antisense transcripts in Arabidopsis. BMC Mol. Biol. 9, 6 (2008).
  • 7
    • 33745080545 scopus 로고    scopus 로고
    • RNA interference is not involved in natural antisense mediated regulation of gene expression in mammals
    • Faghihi, M.A. & Wahlestedt, C. RNA interference is not involved in natural antisense mediated regulation of gene expression in mammals. Genome Biol. 7, R38 (2006).
    • (2006) Genome Biol , vol.7
    • Faghihi, M.A.1    Wahlestedt, C.2
  • 8
    • 34250743796 scopus 로고    scopus 로고
    • Transcriptional interferences in cis natural antisense transcripts of humans and mice
    • Osato, N., Suzuki, Y., Ikeo, K. & Gojobori, T. Transcriptional interferences in cis natural antisense transcripts of humans and mice. Genetics 176, 1299-1306 (2007).
    • (2007) Genetics , vol.176 , pp. 1299-1306
    • Osato, N.1    Suzuki, Y.2    Ikeo, K.3    Gojobori, T.4
  • 9
    • 24644488895 scopus 로고    scopus 로고
    • Natural antisense transcripts with coding capacity in Arabidopsis may have a regulatory role that is not linked to double-stranded RNA degradation
    • Jen, C.H., Michalopoulos, I., Westhead, D.R. & Meyer, P. Natural antisense transcripts with coding capacity in Arabidopsis may have a regulatory role that is not linked to double-stranded RNA degradation. Genome Biol. 6, R51 (2005).
    • (2005) Genome Biol , vol.6
    • Jen, C.H.1    Michalopoulos, I.2    Westhead, D.R.3    Meyer, P.4
  • 10
    • 0033883114 scopus 로고    scopus 로고
    • Heritable gene silencing in Drosophila using double-stranded RNA
    • Kennerdell, J.R. & Carthew, R.W. Heritable gene silencing in Drosophila using double-stranded RNA. Nat. Biotechnol. 18, 896-898 (2000).
    • (2000) Nat. Biotechnol , vol.18 , pp. 896-898
    • Kennerdell, J.R.1    Carthew, R.W.2
  • 11
    • 0024850486 scopus 로고
    • The conditional inhibition of gene expression in cultured Drosophila cells by antisense RNA
    • Bunch, T.A. & Goldstein, L.S. The conditional inhibition of gene expression in cultured Drosophila cells by antisense RNA. Nucleic Acids Res. 17, 9761-9782 (1989).
    • (1989) Nucleic Acids Res , vol.17 , pp. 9761-9782
    • Bunch, T.A.1    Goldstein, L.S.2
  • 12
    • 38149071979 scopus 로고
    • Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs
    • 2007
    • Ruby, J.G. et al. Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs. Genome Res. 17, 1850-1864 (2007).
    • (1850) Genome Res , vol.17
    • Ruby, J.G.1
  • 13
    • 38149022486 scopus 로고    scopus 로고
    • Functionally distinct regulatory RNAs generated by bidirectional transcription and processing of microRNA loci
    • Tyler, D.M. et al. Functionally distinct regulatory RNAs generated by bidirectional transcription and processing of microRNA loci. Genes Dev. 22, 26-36 (2008).
    • (2008) Genes Dev , vol.22 , pp. 26-36
    • Tyler, D.M.1
  • 14
    • 44349084754 scopus 로고    scopus 로고
    • The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs
    • publication 7 May, doi:10.1038/nature07015
    • Okamura, K. et al. The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs. Nature advance online publication 7 May 2008 (doi:10.1038/nature07015).
    • (2008) Nature advance online
    • Okamura, K.1
  • 15
    • 44349174824 scopus 로고    scopus 로고
    • Endogenous RNA interference provides a somatic defense against Drosophila transposons
    • in the press
    • Chung, W.J., Okamura, K., Martin, R. & Lai, E.C. Endogenous RNA interference provides a somatic defense against Drosophila transposons. Curr. Biol. (in the press).
    • Curr. Biol
    • Chung, W.J.1    Okamura, K.2    Martin, R.3    Lai, E.C.4
  • 16
    • 0041941514 scopus 로고    scopus 로고
    • The small RNA profile during Drosophila melanogaster development
    • Aravin, A.A. et al. The small RNA profile during Drosophila melanogaster development. Dev. Cell 5, 337-350 (2003).
    • (2003) Dev. Cell , vol.5 , pp. 337-350
    • Aravin, A.A.1
  • 17
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • Elbashir, S.M., Lendeckel, W. & Tuschl, T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev. 15, 188-200 (2001).
    • (2001) Genes Dev , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 18
    • 0037711556 scopus 로고    scopus 로고
    • Making a better RNAi vector for Drosophila: Use of intron spacers
    • Lee, Y.S. & Carthew, R.W. Making a better RNAi vector for Drosophila: use of intron spacers. Methods 30, 322-329 (2003).
    • (2003) Methods , vol.30 , pp. 322-329
    • Lee, Y.S.1    Carthew, R.W.2
  • 19
    • 33746502166 scopus 로고    scopus 로고
    • A distinct small RNA pathway silences selfish genetic elements in the germline
    • Vagin, V.V. et al. A distinct small RNA pathway silences selfish genetic elements in the germline. Science 313, 320-324 (2006).
    • (2006) Science , vol.313 , pp. 320-324
    • Vagin, V.V.1
  • 20
    • 38349081145 scopus 로고    scopus 로고
    • Argonaute loading improves the 5′ precision of both MicroRNAs and their miRNA strands in flies
    • Seitz, H., Ghildiyal, M. & Zamore, P.D. Argonaute loading improves the 5′ precision of both MicroRNAs and their miRNA strands in flies. Curr. Biol. 18, 147-151 (2008).
    • (2008) Curr. Biol , vol.18 , pp. 147-151
    • Seitz, H.1    Ghildiyal, M.2    Zamore, P.D.3
  • 21
    • 44449096738 scopus 로고    scopus 로고
    • Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells
    • doi:10.1126/science.1157396 10 April
    • Ghildiyal, M. et al. Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells. Science published online, doi:10.1126/science.1157396 (10 April 2008).
    • (2008) Science published online
    • Ghildiyal, M.1
  • 22
    • 34447291602 scopus 로고    scopus 로고
    • The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC
    • Horwich, M.D. et al. The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC. Curr. Biol. 17, 1265-1272 (2007).
    • (2007) Curr. Biol , vol.17 , pp. 1265-1272
    • Horwich, M.D.1
  • 23
    • 33846810192 scopus 로고    scopus 로고
    • A novel repeat-associated small interfering RNA-mediated silencing pathway downregulates complementary sense gypsy transcripts in somatic cells of the Drosophila ovary
    • Pelisson, A., Sarot, E., Payen-Groschene, G. & Bucheton, A. A novel repeat-associated small interfering RNA-mediated silencing pathway downregulates complementary sense gypsy transcripts in somatic cells of the Drosophila ovary. J. Virol. 81, 1951-1960 (2007).
    • (2007) J. Virol , vol.81 , pp. 1951-1960
    • Pelisson, A.1    Sarot, E.2    Payen-Groschene, G.3    Bucheton, A.4
  • 24
    • 34447642555 scopus 로고    scopus 로고
    • Sorting of Drosophila small silencing RNAs
    • Tomari, Y., Du, T. & Zamore, P.D. Sorting of Drosophila small silencing RNAs. Cell 130, 299-308 (2007).
    • (2007) Cell , vol.130 , pp. 299-308
    • Tomari, Y.1    Du, T.2    Zamore, P.D.3
  • 25
    • 28944439309 scopus 로고    scopus 로고
    • Animal microRNAs confer robustness to gene expression and have a significant impact on 3′UTR evolution
    • Stark, A., Brennecke, J., Bushati, N., Russell, R.B. & Cohen, S.M. Animal microRNAs confer robustness to gene expression and have a significant impact on 3′UTR evolution. Cell 123, 1133-1146 (2005).
    • (2005) Cell , vol.123 , pp. 1133-1146
    • Stark, A.1    Brennecke, J.2    Bushati, N.3    Russell, R.B.4    Cohen, S.M.5
  • 26
    • 20444365683 scopus 로고    scopus 로고
    • GOToolBox: Functional analysis of gene datasets based on Gene Ontology
    • Martin, D. et al. GOToolBox: functional analysis of gene datasets based on Gene Ontology. Genome Biol. 5, R101 (2004).
    • (2004) Genome Biol , vol.5
    • Martin, D.1
  • 28
    • 22744433240 scopus 로고    scopus 로고
    • Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein
    • Forstemann, K. et al. Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein. PLoS Biol. 3, e236 (2005).
    • (2005) PLoS Biol , vol.3
    • Forstemann, K.1
  • 29
    • 22744454230 scopus 로고    scopus 로고
    • Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells
    • Saito, K., Ishizuka, A., Siomi, H. & Siomi, M.C. Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells. PLoS Biol. 3, e235 (2005).
    • (2005) PLoS Biol , vol.3
    • Saito, K.1    Ishizuka, A.2    Siomi, H.3    Siomi, M.C.4
  • 30
    • 23044462450 scopus 로고    scopus 로고
    • Dicer-1 and R3D1-L catalyze microRNA maturation in
    • Jiang, F. et al. Dicer-1 and R3D1-L catalyze microRNA maturation in. Drosophila. Genes Dev. 19, 1674-1679 (2005).
    • (2005) Drosophila. Genes Dev , vol.19 , pp. 1674-1679
    • Jiang, F.1
  • 31
    • 0141868916 scopus 로고    scopus 로고
    • r2d2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway
    • Liu, Q. et al. r2d2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway. Science 301, 1921-1925 (2003).
    • (2003) Science , vol.301 , pp. 1921-1925
    • Liu, Q.1
  • 33
    • 44349130233 scopus 로고    scopus 로고
    • Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes
    • publication 10 April, doi:10.1038/nature06908
    • Watanabe, T. et al. Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes. Nature advance online publication 10 April 2008 (doi:10.1038/nature06908).
    • (2008) Nature advance online
    • Watanabe, T.1
  • 34
    • 33645967150 scopus 로고    scopus 로고
    • AGO1 homeostasis entails coexpression of MIR168 and AGO1 and preferential stabilization of miR168 by AGO1
    • Vaucheret, H., Mallory, A.C. & Bartel, D.P. AGO1 homeostasis entails coexpression of MIR168 and AGO1 and preferential stabilization of miR168 by AGO1. Mol. Cell 22, 129-136 (2006).
    • (2006) Mol. Cell , vol.22 , pp. 129-136
    • Vaucheret, H.1    Mallory, A.C.2    Bartel, D.P.3
  • 35
    • 33845688601 scopus 로고    scopus 로고
    • A diverse and evolutionarily fluid set of microRNAs in Arabidopsis thaliana
    • Rajagopalan, R., Vaucheret, H., Trejo, J. & Bartel, D.P. A diverse and evolutionarily fluid set of microRNAs in Arabidopsis thaliana. Genes Dev. 20, 3407-3425 (2006).
    • (2006) Genes Dev , vol.20 , pp. 3407-3425
    • Rajagopalan, R.1    Vaucheret, H.2    Trejo, J.3    Bartel, D.P.4
  • 36
    • 0035498967 scopus 로고    scopus 로고
    • The RNA-binding protein Tsunagi interacts with Mago Nashi to establish polarity and localize oskar mRNA during Drosophila oogenesis
    • Mohr, S.E., Dillon, S.T. & Boswell, R.E. The RNA-binding protein Tsunagi interacts with Mago Nashi to establish polarity and localize oskar mRNA during Drosophila oogenesis. Genes Dev. 15, 2886-2899 (2001).
    • (2001) Genes Dev , vol.15 , pp. 2886-2899
    • Mohr, S.E.1    Dillon, S.T.2    Boswell, R.E.3
  • 37
    • 33845866637 scopus 로고    scopus 로고
    • Peng, J.C. & Karpen, G.H. H3K9 methylation and RNA interference regulate nucleolar organization and repeated DNA stability. Nat. Cell Biol. 9, 25-35 (2007).
    • Peng, J.C. & Karpen, G.H. H3K9 methylation and RNA interference regulate nucleolar organization and repeated DNA stability. Nat. Cell Biol. 9, 25-35 (2007).
  • 38
    • 23044470630 scopus 로고    scopus 로고
    • Drosophila argonaute-2 is required early in embryogenesis for the assembly of centric/centromeric heterochromatin, nuclear division, nuclear migration, and germ-cell formation
    • Deshpande, G., Calhoun, G. & Schedl, P. Drosophila argonaute-2 is required early in embryogenesis for the assembly of centric/centromeric heterochromatin, nuclear division, nuclear migration, and germ-cell formation. Genes Dev. 19, 1680-1685 (2005).
    • (2005) Genes Dev , vol.19 , pp. 1680-1685
    • Deshpande, G.1    Calhoun, G.2    Schedl, P.3
  • 39
    • 44349159416 scopus 로고    scopus 로고
    • Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes
    • publication, doi:10.1038/nature06904 10 April
    • Tam, O.H. et al. Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes. Nature advance online publication, doi:10.1038/nature06904 (10 April 2008).
    • (2008) Nature advance online
    • Tam, O.H.1
  • 40
    • 0035955361 scopus 로고    scopus 로고
    • An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    • Lau, N.C., Lim, L., Weinstein, E. & Bartel, D.P. An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294, 858-862 (2001).
    • (2001) Science , vol.294 , pp. 858-862
    • Lau, N.C.1    Lim, L.2    Weinstein, E.3    Bartel, D.P.4
  • 41
    • 34447107760 scopus 로고    scopus 로고
    • The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila
    • Okamura, K., Hagen, J.W., Duan, H., Tyler, D.M. & Lai, E.C. The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila. Cell 130, 89-100 (2007).
    • (2007) Cell , vol.130 , pp. 89-100
    • Okamura, K.1    Hagen, J.W.2    Duan, H.3    Tyler, D.M.4    Lai, E.C.5
  • 42
    • 38549131376 scopus 로고    scopus 로고
    • The UCSC Genome Browser Database: 2008 update
    • Karolchik, D. et al. The UCSC Genome Browser Database: 2008 update. Nucleic Acids Res. 36, D773-D779 (2008).
    • (2008) Nucleic Acids Res , vol.36
    • Karolchik, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.