Overexpression of taurine transporter in Chinese hamster ovary cells can enhance cell viability and product yield, while promoting glutamine consumption

Biotechnology and Bioengineering

Volumn 107, Issue 6, 2010, Pages 998-1003

  Tabuchi, Hisahiro ^a   Sugiyama, Tomoya ^a   Tanaka, Saeko ^a   Tainaka, Satoshi ^a  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Apoptosis; CHO DXB11; Glutamine; Glutathione; IPA; TAUT

Indexed keywords

APOPTOSIS; CHO-DXB11; GLUTAMINE; GLUTATHIONES; IPA; TAUT;

AMINO ACIDS; CELL DEATH; METABOLISM; MICROBIOLOGY; MONOCLONAL ANTIBODIES; PHYSIOLOGY;

CELL CULTURE;

AMMONIA; GLUTAMINE; LACTIC ACID; MESSENGER RNA; MONOCLONAL ANTIBODY; TAURINE; TAURINE TRANSPORTER; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIBODY TITER; APOPTOSIS; ARTICLE; BIOREACTOR; CELL CULTURE; CELL METABOLISM; CELL VIABILITY; CHINESE HAMSTER; CONTROLLED STUDY; CULTURE MEDIUM; FEMALE; GENE OVEREXPRESSION; NONHUMAN; OVARY CELL; PLASMID; UPREGULATION;

ANIMALS; BIOTECHNOLOGY; CELL CULTURE TECHNIQUES; CELL SURVIVAL; CHO CELLS; CRICETINAE; CRICETULUS; GENE EXPRESSION; GLUTAMINE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS;

CRICETULUS GRISEUS;

EID: 78149452108     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.22880     Document Type: Article

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