Angiotensin II blockade: How its molecular targets may signal to mitochondria and slow aging. Coincidences with calorie restriction and mTOR inhibition

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 309, Issue 1, 2015, Pages H15-H44

  de Cavanagh, Elena M V ^a   Inserra, Felipe ^a   Ferder, León ^b  

^a UNIVERSIDAD AUSTRAL   (Argentina)

^b PONCE SCHOOL OF MEDICINE   (Puerto Rico)

Author keywords

Caloric restriction; Mechanistic target of rapamycin; Renin angiotensin system; Vitamin D

Indexed keywords

ANGIOTENSIN II; CALCIUM; FIBROBLAST GROWTH FACTOR 23; HISTONE; KLOTHO PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; PHOSPHATE; RAPAMYCIN; SIRTUIN; VITAMIN D; VITAMIN D RECEPTOR; BETA GLUCURONIDASE; CALCITRIOL RECEPTOR; FIBROBLAST GROWTH FACTOR; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; TARGET OF RAPAMYCIN KINASE;

AGING; CALORIC RESTRICTION; CELL GROWTH; CHRONIC DISEASE; DEACETYLATION; HUMAN; INTRACELLULAR SIGNALING; LIFESPAN; METABOLIC REGULATION; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REVIEW; SURVIVAL; UPREGULATION; VITAMIN METABOLISM; ANTAGONISTS AND INHIBITORS; LONGEVITY; METABOLISM; SIGNAL TRANSDUCTION;

AGING; ANGIOTENSIN II; CALORIC RESTRICTION; FIBROBLAST GROWTH FACTORS; GLUCURONIDASE; HUMANS; LONGEVITY; MITOCHONDRIA; MULTIPROTEIN COMPLEXES; RECEPTORS, CALCITRIOL; RENIN-ANGIOTENSIN SYSTEM; SIGNAL TRANSDUCTION; SIRTUINS; TOR SERINE-THREONINE KINASES; VITAMIN D;

EID: 84935417692     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00459.2014     Document Type: Review

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