Oxidative, glycoxidative and lipoxidative damage to rat heart mitochondrial proteins is lower after 4 months of caloric restriction than in age-matched controls

Mechanisms of Ageing and Development

Volumn 123, Issue 11, 2002, Pages 1437-1446

  Pamplona, Reinald ^c   Portero Otín, Manuel ^c   Requena, Jesus ^b   Gredilla, Ricardo ^a   Barja, Gustavo ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c UNIVERSITY OF LLEIDA   (Spain)

Author keywords

Aging; Carbonyl stress; Fatty acids; Free radicals; Malondialdehyde; Protein carbonyls; Protein damage

Indexed keywords

6 N CARBOXYMETHYLLYSINE; ALDEHYDE DERIVATIVE; AMINOADIPIC ACID; CARBONYL DERIVATIVE; FATTY ACID; GLUTAMIC ACID; LIPID; LYSINE DERIVATIVE; MARKER; MITOCHONDRIAL PROTEIN; N EPSILON CARBOXYETHYLLYSINE; N EPSILON MALONDIALDEHYDE LYSINE; OXYGEN RADICAL; UNCLASSIFIED DRUG; 2 AMINOGLUTARALDEHYDIC ACID; ALDEHYDE; BIOLOGICAL MARKER; DRUG DERIVATIVE; GLUTAMIC ACID DERIVATIVE; GLUTAMIC ACID GAMMA-SEMIALDEHYDE; LYSINE; N(6) (1 CARBOXYETHYL)LYSINE; N(6) CARBOXYMETHYLLYSINE; N(6)-(1-CARBOXYETHYL)LYSINE; N(6)-CARBOXYMETHYLLYSINE; N(EPSILON) (MALONDIALDEHYDE)LYSINE; N(EPSILON)-(MALONDIALDEHYDE)LYSINE;

AGING; ANIMAL CELL; ARTICLE; CALORIC RESTRICTION; CONTROLLED STUDY; DECOMPOSITION; FATTY ACID ANALYSIS; GAS CHROMATOGRAPHY; HEART MITOCHONDRION; LIPID COMPOSITION; LIPID PEROXIDATION; MALE; MASS SPECTROMETRY; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN MODIFICATION; RAT; TISSUE LEVEL; ANIMAL; CALORIC INTAKE; METABOLISM; PHYSIOLOGY; REFERENCE VALUE; TIME; WISTAR RAT;

ANIMALIA;

ALDEHYDES; ANIMALS; BIOLOGICAL MARKERS; ENERGY INTAKE; GLUTAMATES; LYSINE; MALE; MITOCHONDRIA, HEART; MITOCHONDRIAL PROTEINS; OXIDATIVE STRESS; RATS; RATS, WISTAR; REFERENCE VALUES; TIME FACTORS;

EID: 0036756755     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0047-6374(02)00076-3     Document Type: Article

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