Rapamycin doses sufficient to extend lifespan do not compromise muscle mitochondrial content or endurance

Aging

Volumn 5, Issue 7, 2013, Pages 539-550

  Ye, Lan ^a,b   Widlund, Anne L ^b,c   Sims, Carrie A ^b,d   Lamming, Dudley W ^e   Guan, Yuxia ^d   Davis, James G ^b   Sabatini, David M ^e,f,g   Harrison, David E ^h   Vang, Ole ^c   Baur, Joseph A ^b  

^a NANJING MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c ROSKILDE UNIVERSITY   (Denmark)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^f MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^g BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^h JACKSON LABORATORY   (United States)

Author keywords

Biogenesis; Endurance; Longevity; mTOR; PGC 1alpha; Sarcopenia

Indexed keywords

EID: 84881102986     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100576     Document Type: Article

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